Polarization of cytokine responses in B- and T-lymphocytes during Staphylococcus aureus infection

Microbial Pathogenesis

Volumn 35, Issue 3, 2003, Pages 119-124

  Gjertsson, Inger ^a   Foster, Simon ^b   Tarkowski, Andrej ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Arthritis; B and T lymphocytes; Intracellular Cytokines; Mice; Staphylococcus aureus

Indexed keywords

ANTIGEN; CD4 ANTIGEN; CYTOKINE; FORMALDEHYDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; PEPTIDOGLYCAN;

ANIMAL CELL; ANIMAL MODEL; ARTHRITIS; ARTICLE; B LYMPHOCYTE; BACTERICIDAL ACTIVITY; CELL POPULATION; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FUNCTIONAL ASSESSMENT; IN VITRO STUDY; INFLAMMATION; INTERFERON PRODUCTION; LEUKOCYTE; LYMPHOCYTE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; SPLEEN CELL; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0042622470     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0882-4010(03)00114-1     Document Type: Article

References (31)

1. Bremell T., Lange S., Yacoub A., Ryden C., Tarkowski A. Experimental Staphylococcus aureus arthritis in mice. Infect Immun. 59:1991;2615.
2. Hultgren O., Eugster H.P., Sedgwick J.D., Korner H., Tarkowski A. TNF/lymphotoxin-alpha double-mutant mice resist septic arthritis but display increased mortality in response to Staphylococcus aureus. J Immunol. 161:1998;5937.
3. Hultgren O., Kopf M., Tarkowski A. Staphylococcus aureus-induced septic arthritis and septic death is decreased in IL-4-deficient mice: role of IL-4 as promoter for bacterial growth. J Immunol. 160:1998;5082.
4. Hultgren O., Kopf M., Tarkowski A. Outcome of Staphylococcus aureus-triggered sepsis and arthritis in IL-4-deficient mice depends on the genetic background of the host. Eur J Immunol. 29:1999;2400.
5. Hultgren O.H., Stenson M., Tarkowski A. Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis. Arthritis Res. 3:2001;41.
6. Hultgren O.H., Svensson L., Tarkowski A. Critical role of signaling through IL-1 receptor for development of arthritis and sepsis during Staphylococcus aureus infection. J Immunol. 168:2002;5207.
7. Zhao Y.X., Nilsson I.M., Tarkowski A. The dual role of interferon-gamma in experimental Staphylococcus aureus septicaemia versus arthritis. Immunology. 93:1998;80.
8. Gjertsson I., Hultgren O.H., Tarkowski A. Interleukin-10 ameliorates the outcome of Staphylococcus aureus arthritis by promoting bacterial clearance. Clin Exp Immunol. 130:2002;409.
9. Verdrengh M., Tarkowski A. Role of neutrophils in experimental septicemia and septic arthritis induced by Staphylococcus aureus. Infect Immun. 65:1997;2517.
10. Verdrengh M., Tarkowski A. Role of macrophages in Staphylococcus aureus-induced arthritis and sepsis. Arthritis Rheum. 43:2000;2276.
11. Abdelnour A., Bremell T., Holmdahl R., Tarkowski A. Role of T lymphocytes in experimental Staphylococcus aureus arthritis. Scand J Immunol. 39:1994;403.
12. Gjertsson I., Hultgren O.H., Stenson M., Holmdahl R., Tarkowski A. Are B lymphocytes of importance in severe Staphylococcus aureus infections? Infect Immun. 68:2000;2431.
13. Robinson D.S., O'Garra A. Further checkpoints in Th1 development. Immunity. 16:2002;755.
14. O'Garra A. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 8:1998;275.
15. Eynon E.E., Parker D.C. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J Exp Med. 175:1992;131.
16. Fuchs E.J., Matzinger P. B cells turn off virgin but not memory T cells. Science. 258:1992;1156.
17. Ronchese F., Hausmann B. B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes. J Exp Med. 177:1993;679.
18. Harris D.P., Haynes L., Sayles P.C., Duso D.K., Eaton S.M., Lepak N.M., Johnson L.L., Swain S.L., Lund F.E. Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat Immunol. 1:2000;475.
19. Koester S.K., Bolton W.E. Intracellular markers. J Immunol Meth. 243:2000;99.
20. Zhao Y.X., Ljungdahl A., Olsson T., Tarkowski A. In situ hybridization analysis of synovial and systemic cytokine messenger RNA expression in superantigen-mediated Staphylococcus aureus arthritis. Arthritis Rheum. 39:1996;959.
21. Zhao Y.X., Abdelnour A., Holmdahl R., Tarkowski A. Mice with the xid B cell defect are less susceptible to developing Staphylococcus aureus-induced arthritis. J Immunol. 155:1995;2067.
22. Abdelnour A., Bremell T., Tarkowski A. Toxic shock syndrome toxin 1 contributes to the arthritogenicity of Staphylococcus aureus. J Infect Dis. 170:1994;94.
23. Zhao Y.X., Abdelnour A., Ljungdahl A., Olsson T., Tarkowski A. Patterns of interferon-gamma mRNA expression in toxic shock syndrome toxin-1 expanded V beta 11+ T lymphocytes. Cell Immunol. 161:1995;28.
24. Zhao Y.X., Tarkowski A. Impact of interferon-gamma receptor deficiency on experimental Staphylococcus aureus septicemia and arthritis. J Immunol. 155:1995;5736.
25. Timmerman C.P., Mattsson E., Martinez-Martinez L., De Graaf L., Van Strijp J.A., Verbrugh H.A., Verhoef J., Fleer A. Induction of release of tumor necrosis factor from human monocytes by staphylococci and staphylococcal peptidoglycans. Infect Immun. 61:1993;4167.
26. Kengatharan K.M., De Kimpe S., Robson C., Foster S.J., Thiemermann C. Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failure. J Exp Med. 188:1998;305.
27. Liu Z.Q., Deng G.M., Foster S., Tarkowski A. Staphylococcal peptidoglycans induce arthritis. Arthritis Res. 3:2001;375.
28. Zhao Y.X., Abdelnour A., Kalland T., Tarkowski A. Overexpression of the T-cell receptor V beta 3 in transgenic mice increases mortality during infection by enterotoxin A-producing Staphylococcus aureus. Infect Immun. 63:1995;4463.
29. Bremell T. Staphylococcus aureus arthritis. In: Departments of Clinical Immunology and Rheumatology. Göteoborg: University of Göteborg; 1994. p. 73.
30. Forsgren A., Sjoquist J. 'Protein A' from S. aureus. I. Pseudo-immune reaction with human gamma-globulin. J Immunol. 97:1966;822.
31. Palmqvist N., Foster T., Tarkowski A., Josefsson E. Protein A is a virulence factor in Staphylococcus aureus arthritis and septic death. Microb Pathog. 33:2002;239.