Determination of the cardiac glycosides digoxin and digitoxin by liquid chromatography combined with isotope-dilution mass spectrometry (LC-IDMS) - A candidate reference measurement procedure

Clinical Laboratory

Volumn 49, Issue 7-8, 2003, Pages 329-343

  Kaiser, Patricia ^a   Kramer, Udo ^a   Meißner, Dieane ^a   Kress, Michael ^a   Wood, William Graham ^a   Reinauer, Hans ^a  

^a Reference Method Laboratories   (Germany)

Author keywords

Caesium adducts; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin; Extraction; LC IDMS; Liquid phase; Quality control; Reference measurement procedure

Indexed keywords

ACETIC ACID ETHYL ESTER; AMMONIUM ACETATE; BUFFER; CARDIAC GLYCOSIDE; CESIUM; DEUTERIUM; DIGITOXIN; DIGOXIN; ETHER DERIVATIVE; FORMIC ACID; METHANOL;

ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DISTILLATION; DRUG BLOOD LEVEL; DRUG ISOLATION; DRUG MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE DILUTION ASSAY; MASS SPECTROMETER; MASS SPECTROMETRY; MEASUREMENT; PH; QUANTITATIVE ANALYSIS; REFERENCE VALUE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; STANDARD; VALIDATION PROCESS;

CALIBRATION; CARDIOTONIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIGITOXIN; DIGOXIN; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

TRIXIS;

EID: 0042531737     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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