Effect of compression force and tablet press speed on the properties of tablets containing high-dose of spray dried plant extracts;Efeito da força e da velocidade de compressão sobre as propriedades de comprimidos contendo alta concentração de extrato seco vegetal

Acta Farmaceutica Bonaerense

Volumn 22, Issue 2, 2003, Pages 147-154

  Soares, Luiz Alberto Lira ^a   Schmidt, Peter Christian ^b   Ortega, George Gonzalez ^c   Petrovick, Pedro Ros ^c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c FEDERAL UNIVERSITY OF RIO GRANDE   (Brazil)

Author keywords

Direct Compression; Maytenus ilicifolia; Response Surface Methodology

Indexed keywords

AEROSIL; MAGNESIUM STEARATE; MAYTENUS ILICIFOLIA EXTRACT; MICROCRYSTALLINE CELLULOSE; PLANT EXTRACT; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG MEGADOSE; MATHEMATICAL MODEL; MAYTENUS; MAYTENUS ILICIFOLIA; RESPONSE SURFACE METHOD; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS; TABLET PROPERTY; VALIDATION PROCESS;

EID: 0042477597     PISSN: 03262383     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Gaudy, D., A., Puech & M. Jacob (1991) Pharm. Acta Helv. 66: 5-10.
2. González Ortega, G. & P.C. Schmidt (1995) Acta Farm. Bonaerense 14: 173-80.
3. De Paula, I.C., G. González Ortega, V.L. Bassani & P.R. Petrovick (1998) Drug. Dev. Ind. Pharm. 24: 235-41.
4. De Souza, K.C.B., P.R. Petrovick, V.L. Bassani & G. González Ortega (2000) Drug. Dev. Ind. Pharm. 26: 331-6.
5. Linden, R., G. González Ortega, P.R. Petrovick & V.L. Bassani (2000) Drug Dev. Ind. Pharm. 26: 441-6.
6. De Souza, T.P., V.L. Bassani, G. González Ortega, T.C.T. Dalla Costa & P.R. Petrovick (2001) Pharmazie. 56: 730-3.
7. Palma, S.D., R.H. Mamzo & D.A. Allemandi (1999) Pharm. Dev. Tech. 4: 523-30.
8. Rocksloh, K., F.R. Rapp, S. Abu Abed, W. Müller, M. Reher, G. Gauglitz & P.C. Schmidt (1999) Drug Dev. Ind. Pharm. 25: 1015-25.
9. Roberts, R.J. & R.C. Rowe (1985) J. Pharm. Pharmacol. 37: 377-84.
10. Myers, H.R. & D.C. Montgomery (1995) Response Surface Methodology: Process and product Optimization Using Designed Experiments. New York: John Wiley.
11. Wherlé, P. (1990) Aspects des analyses multifactoriales des plans d'experiences appliques a l'optimisation et a la validation de formes et de procédés galèniques. Paris: Faculté de Pharmacie de Chateay-Malabry. Tese de Doutorado.
12. Wherlé, P., Ph. Nobelis, A., Cuiné & A. Stamm (1993) Drug Dev. Ind. Pharm. 19: 1637-53.
13. Wherlé, P., B. Magenheim & S. Benita (1995) Eur. J. Pharm. Biopharm. 41: 19-26.
14. Carvalho, E.L.S. (1997) Desenvolvimento de produto seco nebulizado de Maytenus ilicifolia Martius ex Reiss - Celastraceae (espinheira-santa). Porto Alegre: Curso de Pós-Graduação em Ciências Farmacêuticas, UFRGS. Dissertação (Mestrado em Ciências Farmacêuticas).
15. Farmacopéia Brasileira (1988) 4 ed., São Paulo: Andrei.