Lutein interacts with ascorbic acid more frequently than with α-tocopherol to alter biomarkers of oxidative stress in female Zucker obese rats

Journal of Nutrition

Volumn 133, Issue 9, 2003, Pages 2838-2844

  Blakely, Shirley ^a   Herbert, Arnetra ^b   Collins, Michelle ^c   Jenkins, Mamie ^a   Mitchell, Geraldine ^a   Grundel, Erich ^a   O'Neill, Karen R ^a   Khachik, Frederick ^d  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Bldg 142   (United States)

Author keywords

Antioxidants; Ascorbic acid; Carotenoids; Lutein; Obesity; tocopherol

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BIOLOGICAL MARKER; INSULIN; MALONALDEHYDE; SUPEROXIDE DISMUTASE; XANTHOPHYLL;

ANIMAL EXPERIMENT; BIOACCUMULATION; CONFERENCE PAPER; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; FEMALE; INSULIN BLOOD LEVEL; LEAN BODY WEIGHT; LIPID PEROXIDATION; LIVER WEIGHT; NONHUMAN; OBESITY; OXIDATIVE STRESS; RAT; RAT STRAIN; WEIGHT GAIN;

ANIMALIA;

EID: 0042419892     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/133.9.2838     Document Type: Conference Paper

References (44)

1. Halliwell, B. (1984) Oxygen radicals: a common sense look at their nature and medical importance. Lancet 1: 1328-1329.
2. Halliwell, B. (1999) Establishing the significance and optimal intake of dietary antioxidants: the biomarker concept. Nutr. Rev. 57: 104-113.
3. Ames, B. N., Shigenaga, M. K. & Hagen, T. M. (1993) Oxidants, antioxidants and the degenerative diseases of ageing. Proc. Natl. Acad. Sci. U.S.A. 90: 7915-7922.
4. Zino, S., Skeaff, M., Williams, S. & Mann, J. (1997) Randomised controlled trial of effects of fruit and vegetable consumption on plasma concentrations of lipids and antioxidants. Br. Med. J. 314: 1787-1791.
5. Vogel, S., Contois, J. H., Tucker, K. L., Wilson, P. W. F., Schaefer, E. J. & Lammi-Keefe, C. J. (1997) Plasma retinal and plasma and lipoprotein tocopherol and carotenoid concentrations in healthy elderly participants of the Framingham Heart Study. Am. J. Clin. Nutr. 66: 950-958.
6. Öhrvall, M., Tengblad, S. & Vessby, B. (1993) Lower tocopherol serum levels in subjects with abdominal adiposity. J. Intern. Med. 234: 53-60.
7. Narisawa, J., Fukaura, Y., Hasebe, M., Ito, M., Aizawa, R., Murakosi, M., Vemura, S., Khachik, F. & Nishino, H. (1996) Inhibitory effects of natural carotenoids, alpha-carotene, beta-carotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats. Cancer Lett. 107: 137-142.
8. Dwyer, J. H., Mohamad, N., Dwyer, K. M., Hassan, K., Sun, P., Shircore, A., Mama-Levy, S., Hough, G., Wang, X., Drake, T., Noel, C., Merz, B. & Fogelman, A. M. (2001) Oxygenated carotenoid lutein and progression of early atherosclerosis: the Los Angeles atherosclerosis study. Circulation 103: 2922-2927.
9. Bone, R. A., Landrum, J. T., Dixon, Z., Chen, Y. & Llerena, C. M. (2000) Lutein and zeaxanthin in the eyes, serum, and diets of human subjects. Exp. Eye Res. 71: 239-245.
10. Mares-Perlman, J. A., Fisher, A. I., Klein, R., Palta, M., Block, G., Millen, A. E. & Wright, J. D. (2001) Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Am. J. Epidemiol. 153: 424-432.
11. Landrum, J. T. & Bone, R. A. (2001) Lutein, zeaxanthin, and the macular pigment. Arch Biochem. Biophys. 385: 28-40.
12. Hammond, B. R., Ciulla, T. A. & Snodderly, D. M. (2002) Macular pigment density is reduced in obese subjects. Investig. Ophthalmol. Vis. Sci. 43: 47-50.
13. Park, J. S., Chew, B. P. & Wong, T. S. (1998) Dietary lutein absorption from marigold extract is rapid in BALB/c mice. J. Nutr. 128: 1802-1806.
14. 13C tracer to quantify the plasma appearance of a physiological dose of lutein in humans. Lipids 35: 339-348.
15. Taylor, A., Jacques, P. F., Chylack, L. T., Jr., Hankinson, S. E., Khu, P. M., Rogers, G., Friend, J., Tung, W., Wolfe, J. K., Padhye, N. & Willett, W. C. (2002) Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities. Am. J. Clin. Nutr. 75: 540-549.
16. Tauler, P., Aguilo, A., Fuentespina, E., Tur, J. A. & Pons, A. (2002) Diet supplementation with Vitamin E, Vitamin C and beta-carotene cocktail enhances basal neutrophil antioxidant enzymes in athletes. Pflugers Arch. 443: 791-797.
17. Gale, C. R., Ashurst, H. E., Powers, H. J. & Martyn, C. N. (2001) Antioxidant vitamin status and carotid atherosclerosis in the elderly. Am. J. Clin. Nutr. 74: 402-408.
18. 14C] triolein load and lipoprotein lipase activity. Biochem J. 274: 651-656.
19. Laight, D. W., Desai, K. M., Anggard, E. E. & Carrier, M. J. (2000) Endothelial dysfunction accompanies a pro-oxidant, pro-diabetic challenge in the insulin resistant, obese Zucker rat in vivo. Eur. J. Pharmacol. 402: 95-99.
20. Carbo, N., Lopez-Soriano, F. J. & Argiles, J. M. (1991) Glucose handling by hepatocytes from obese Zucker rats. Biosci Rep. 11: 285-292.
21. Peters, E. M., Anderson, R., Nieman, D. C., Fickl, H. & Jogessar, V. (2001) Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running. Int. J. Sports Med. 22: 537-543.
22. National Research Council (1996) Guide for the Care and Use of Laboratory Animals. Institute of Laboratory Resources, Commission on Life Sciences, National Academy Press, Washington, DC.
23. Reeves, P. G., Nielsen, F. H. & Fahey, G. C. (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 123: 1939-1951.
24. Blakely, S. R., Mitchell, G. V., Jenkins, M. Y., Grundel, E. & Whittaker, P. (1991) Canthaxanthin and excess vitamin A alter α-tocopherol, carotenoid and iron status in adult rats. J. Nutr. 121: 1649-1655.
25. Brown, E. D., Blakely, S. R., Babu, U., Grundel, E. & Mitchell, G. V. (1997) Vegetable concentrates interact with canthaxanthin to affect carotenoid bioavailability and superoxide dismutase activity but not immune response in rats. Nutr. Res. 17: 989-998.
26. Meister A. (1994) Glutathione-ascorbic acid antioxidant system in animals. J. Biol. Chem. 269: 9397-9400.
27. Prohaska, J. R., Downing, S. W. & Ludasewyz, O. A. (1983) Chronic dietary copper deficiency alters biochemical and morphological properties of mouse lymphoid tissues. J. Nutr. 113: 1583-1590.
28. Asayama, K., Kooy, N. W. & Burr, I. M. (1986) Effect of vitamin E deficiency and selenium deficiency on insulin secretory reserve and free radical scavenging systems in islets: decreases of islet manganosuperoxide dismutase. J. Lab. Clin. Med. 107: 459-464.
29. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
30. Ohkawa, H., Ohishi, N. & Yagi, K. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95: 351-358.
31. Tietze, F. (1969) Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 27: 502-522.
32. Khachik F., Spangler C. J., Smith, J. C., Jr., Canfield L. M., Pfander H. & Steck A. (1997) Identification, quantification and relative concentrations of carotenoids and their metabolites in human milk and serum. Anal. Chem. 69: 1873-1881.
33. Olson, J. A. (1979) A simple dual assay for vitamin A and carotenoids in human liver. Nutr. Rep. Int. 19: 808-813.
34. Schaffert, R. R. & Kingsley, G. R. (1955) A rapid simple method for determination of reduced, dehydro-, and total ascorbic acid in biological material. J. Biol. Chem. 212: 59-68.
35. Berson, S. A. & Yallow, R. S., eds. (1973) Methods in Investigative and Diagnostic Endocrinology. Vol. 2B, Pt III, Chapter 3. American Elsevier Publishing Company, New York, NY.
36. Einot, I. & Gabriel, K. R. (1975) A study of the powers of several methods of multiple comparisons. J. Am. Stat. Assoc. 70: 351-361.
37. Soltys, K., Dikdan, G. & Koneru, B. (2001) Oxidative stress in fatty livers of obese Zucker rats: rapid amelioration and improved tolerance to warm ischemia with tocopherol. Hepatology 34: 13-18.
38. Vincent, H. K., Powers, S. K., Stewart, D. J., Shanely, R. A., Demirel, H. & Naito, H. (1999) Obesity is associated with increased myocardial oxidative stress. Int. J. Obes. 23: 67-74.
39. Argiles, J. M. (1989) The obese Zucker rat: a choice for fat metabolism. 1968-1988: twenty years of research on the insights of the Zucker mutation. Prog. Lipid Res. 28: 53-66.
40. van het Hof, K. H., Brouwer, I. A., West, C. E., Haddeman, E., Steegers-Theunissen, R. P., van Dusseldorp, M., Weststrate, J. A., Eskes, T. K. & Hautvast, J.G. (1999) Bioavailability of lutein from vegetables is 5 times higher than that of beta-carotene. Am. J. Clin. Nutr. 70: 261-268.
41. Siems, W. G., Sommerburg, O. & van Kuijk, F. J. (1999) Lycopene and beta-carotene decompose more rapidly than lutein and zeaxanthin upon exposure to various pro-oxidants in vitro. BioFactors. 10: 105-113.
42. Woodall, A. A., Lee, S. W., Weesie, R. J., Jackson, M. J. & Britton G. (1997) Oxidation of carotenoids by free radicals: relationship between structure and reactivity. Biochim. Biophys. Acta 1336: 33-42.
43. Young, A. J. & Lowe, G. M. (2001) Antioxidant and prooxidant properties of carotenoids. Arch. Biochim. Biophys. 385: 20-27.
44. Chen, C., Suh, J., Carr, A. C., Morrow, J. D., Zeind, J. & Frei, Balz. (2000) Vitamin C suppresses oxidative damage in vivo, even in the presence of iron overload. Am. J. Physiol. 279: E1406-E1412.