Search for new lead structures in the isoxazole heterocyclic system

Acta Poloniae Pharmaceutica - Drug Research

Volumn 60, Issue 3, 2003, Pages 225-228

  Ryng, Stanisław ^a   Zimecki, Michał ^b   Fedorowicz, Adam ^c   Jezierska, Aneta ^c   Głowiak, Tadeusz ^c  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^c UNIVERSITY OF WROC AW   (Poland)

Author keywords

Crystallography; Immunomodulatory activity; Immunosuppressor; Isoxazoles; Quantitative structure activity relationships; Quantum chemical calculations

Indexed keywords

ANILIDE; CARBOXYLIC ACID DERIVATIVE; CYCLOSPORIN A; HETEROCYCLIC COMPOUND; IMMUNOSUPPRESSIVE AGENT; ISOXAZOLE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MODEL; QUANTUM CHEMISTRY; STRUCTURE ACTIVITY RELATION; TH2 CELL; X RAY ANALYSIS;

ANTIBODY FORMATION; CELLS, CULTURED; ELECTROCHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN; IMMUNITY, CELLULAR; IMMUNOSUPPRESSIVE AGENTS; ISOXAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0042389640     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Ryng S., Machoń Z., Wieczorek Z., Zimecki M., Mokrosz M.J.: Eur. J. Med. Chem. 33, 831 (1998).
2. Ryng S., Machoń Z, Wieczorek Z., Zimecki M., Głowiak T.: Arch. Pharm. Pharm. Med. Chem. 330, 319 (1997).
3. Ryng S., Głowiak T.: J. Chem. Crystallogr. 28 (5), 373 (1998).
4. Scrocco E., Tomasi J.: Adv. Quantum Chem. 11, 115 (1978).
5. Williams D.E., Yan J.M.: Adv. Atomic Mol. Phys. 23, 87 (1988).
6. Frisch M.J., Trucks G.W., Schlegel H.B., Gill P.M.W., Johnson B.G., Robb M.A., Cheesman J.R., Keith T., Petersson G.A., Montgomery J.A., Taghavachari K., Al.-Laham M.A., Zakrzewski V.G., Ortiz J.V., Foresman J.B., Cioslowski J., Stefanov B.B., Nanayakkara A., Challacombe M., Peng C.Y., Ayala P.Y., Chen W., Wong M.W., Andres J.L., Replogle E.S., Gomperts R., Martin R.L., Fox D.J., Binkley J.S., Defrees D.J., Baker J., Stewart J.P., Head-Gordon M., Gonzalez C., Pople J.A.: Gaussian, Inc., Pittsburgh PA ( 1995).
7. Ryng St., Zimecki M., Fedorowicz A., Koll A.: Quantitative Structure Activity Relationships 18, 236 (1999).
8. Fedorowicz A., Jezierska A., Ryng St.: Internet J. Chem. 4, 7 (2001).