Screening for metabolites from Penicillium novae-zeelandiae displaying radical-scavenging activity and oxidative mutagenicity: Isolation of gentisyl alcohol

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 539, Issue 1-2, 2003, Pages 187-194

  Alfaro, Cristina ^a   Urios, Amparo ^b   González, M Carmen ^a   Moya, Pilar ^a   Blanco, Manuel ^b  

^a UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

Anti oxidants; DPPH radical scavenging activity; Escherichia coli IC203; Oxidative mutagenesis; OxyR; Penicillium novae zeelandiae

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,5 DIHYDROXYBENZYL ALCOHOL; 3 HYDROXYBENZYL ALCOHOL; ANTIMUTAGENIC AGENT; ANTIOXIDANT; ASCORBIC ACID; CATALASE; CATECHOL; CYSTEINE; ETHIDIUM; MUTAGENIC AGENT; PATULIN; PEROXIREDOXIN; SCAVENGER; SUPEROXIDE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BIOASSAY; CELL FREE SYSTEM; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; ESCHERICHIA COLI; MUTAGENESIS; MUTAGENICITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PENICILLIUM; PRIORITY JOURNAL; TRANSCRIPTION INITIATION;

ESCHERICHIA COLI; PENICILLIUM; PENICILLIUM NOVAE-ZEELANDIAE;

EID: 0042388504     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(03)00166-9     Document Type: Article

References (25)

1. Ishikawa Y., Morimoto K., Iseki S. Atrovenetin as a potent antioxidant compound from Penicillium species. J. Am. Oil Chem. Soc. 68:1991;666-668.
2. Ishikawa Y., Morimoto K., Sada T., Fujiwara T. Aurantionone produced by Penicillium aurantio-virens, and its antioxidant activity. Yukagaku. 41:1992;1107-1110.
3. Hayashi K., Suzuki K., Kawaguchi M., Nakajima T., Suzuki T., Numata M., Nakamura T. Isolation of an antioxidant fron Penicillium roquefortii IFO 5956. Biosci. Biotech. Biochem. 59:1995;319-320.
4. Mitscher L.A., Telikepalli H., McGhee E., Shankel D.M. Natural antimutagenic agents. Mutat. Res. 350:1996;143-152.
5. Pillai S.P., Menon S.R., Mitscher L.A., Pillai C.A., Shankel D.M. Umbelliferone analogues and their potential to inhibit benzo(a)pyrene- and hydrogen peroxide-induced mutations. J. Nat. Prod. 62:1999;1358-1362.
6. Ancerewicz J., Migliavacca E., Carrupt P.-A., Testa B., Brée F., Zini R., Tillement J.-P., Labidalle S., Guyot D., Chauvet-Monges A.-M., Crevat A., Le Ridant A. Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants. Free Radical Biol. Med. 25:1998;113-120.
7. Hirota A., Taki S., Kawaii S., Yano M., Abe N. 1,1-diphenyl-2-picrylhydrazyl radical-scavenging compounds from soybean miso and antiproliferative activity of isoflavones from soybean miso toward the cancer cell lines. Biosci. Biotech. Biochem. 64:2000;1038-1040.
8. Mortelmans K., Riccio E.S. The bacterial tryptophan reverse mutation assay with Escherichia coli WP2. Mutat. Res. 455:2000;61-69.
9. Blanco M., Urios A., Martínez A. New Escherichia coli WP2 tester strains highly sensitive to reversion by oxidative mutagens. Mutat. Res. 413:1998;95-101.
10. Christman M.F., Morgan R.W., Jacobson F.S., Ames B.N. Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium. Cell. 41:1985;753-762.
11. Storz G., Tartaglia L.A., Ames B.N. Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation. Science. 248:1990;189-194.
12. Martínez A., Urios A., Blanco M. Mutagenicity of thiol compounds in Escherichia coli WP2 tester strain IC203, deficient in OxyR: effects of S9 fractions from rat liver and kidney. Mutat. Res. 446:1999;205-213.
13. + parent WP2 uvrA/pKM101: detection of 31 oxidative mutagens. Mutat. Res. 467:2000;41-53.
14. R.J. Cole, R.H. Cox, in: Handbook of Toxic Fungal Metabolites, Academic Press, New York, 1981, pp. 510-526.
15. Ishikawa Y., Morimoto K., Hamasaki T. Gentisyl alcohol produced by Penicillium commune, a potent antioxidant and synergist for tocopherol. J. Jpn. Oil Chem. Soc. 35:1986;13-16.
16. Takao T., Kitatani F., Watanabe N., Yagi A., Sakata K. A simple screening method for antioxidants produced by marine bacteria from fish and shellfish. Biosci. Biotech. Biochem. 58:1994;1780-1783.
17. Hirota A., Morimitsu Y., Hojo H. New antioxidative indophenol-reducing phenol compounds isolated from Mortierella sp. fungus. Biosci. Biotech. Biochem. 64:2000;1038-1040.
18. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutat. Res. 113:1983;173-215.
19. Carter W.O., Narayanan P.K., Robinson J.P. Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells. J. Leukoc. Biol. 55:1994;253-258.
20. Priest J.W., Light R.J. Applications of high-performance liquid chromatography to quantitation of metabolites and enzymes of the patulin pathway from Penicillium patulum. J. Chromatogr. A. 13:1990;237-246.
21. Makino M., Endoh T., Ogawa Y., Watanabe K., Fujimoto Y. Studies on the metabolites of Penicillium vulpinum. Heterocycles. 48:1998;1931-1934.
22. Sakamura S., Chida T., Ito J., Sakai R. Isolation and identification of 6-methylsalicylic acid and gentisyl alcohol from Phyllosticta sp. Agric. Biol. Chem. 35:1971;1810-1811.
23. Seaver L.C., Imlay J.A. Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli. J. Bacteriol. 183:2001;7173-7181.
24. Waleh N.S., Rapport S.J., Mortelmans K. Development of a toxicity test to be coupled to the Ames Salmonella assay and the method of construction of the required strains. Mutat. Res. 97:1982;247-256.
25. Stich H.F. The beneficial and hazardous effects of simple phenolic compounds. Mutat. Res. 259:1991;307-324.