Regiospecific naphthalene monohydroxylation by a recombinant yeast producing a P4501A1-yeast reductase fused enzyme

Enzyme and Microbial Technology

Volumn 33, Issue 5, 2003, Pages 606-611

  Shimizu, Masatoshi ^a,b   Lilly, Malcolm D ^a   Woodley, John M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b SUMITOMO CHEMICAL CO LTD   (Japan)

Author keywords

Biocatalysis; Naphthalene monohydroxylation; Recombinant yeast

Indexed keywords

HYDROXYLATION; NAPHTHALENE; YEAST;

BIOTRANSFORMATION;

ENZYME KINETICS;

1 NAPHTHOL; CYTOCHROME P450 1A1; FUNGAL ENZYME; NAPHTHALENE DERIVATIVE;

ARTICLE; BIOTRANSFORMATION; CELL FRACTIONATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HYDROXYLATION; NONHUMAN; SACCHAROMYCES CEREVISIAE; SOLID; YEAST;

EID: 0042381549     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(03)00185-6     Document Type: Article

References (11)

1. Ballard DGW, Courtis A, Shirley IM, Taylor SC. A biotech route to polyphenylene. J Chem Soc Chem Commun 1983;954-5.
2. Brazier A.J., Lilly M.D., Herbert A.B. Toluene cis-glycol synthesis by Pseudomonas putida: kinetic data for reactor evaluation. Enzyme Microb. Technol. 12:1990;90-94.
3. Harrop A.J., Woodley J.M., Lilly M.D. Production of naphthalene-cis-glycol by Pseudomonas putida in the presence of organic solvents. Enzyme Microb. Technol. 14:1992;725-730.
4. Omori T., Matsubara M., Masuda S., Kodama T. Production of 4,5-dihydro-4,5-dihydroxyphthalate. Appl. Microbiol. Biotechnol. 35:1991;431.
5. Guengerich F.P. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res. 48:1988;2946-2954.
6. Parke DV, Ioannides C, Lewis DFV. The role of the P450 in the detoxication and activation of drugs and other chemicals. Can J Physiol Pharmacol 1991;69:537-49.
7. Sakaki T., Kominami S., Takemori S., Ohkawa H., Akiyoshi-Shibata M., Yabusaki Y. Kinetic studies on a genetically engineered fused enzyme between rat cytochrome P4501A1 and yeast NADPH-P450 reductase. Biochemistry. 33:1994;4933-4939.
8. Jones R.P., Greenfield P.F. Specific and non-specific inhibitory effects of ethanol on yeast growth. Enzyme Microb. Technol. 9:1986;334-338.
9. Lin K.H., Iijima S., Shimizu K., Hishinuma F., Kobayashi T. Control of gene expression from the SUC2 promoter of Saccharomyces cerevisiae with the aid of a glucose analyser. Appl. Microbiol. Biotechnol. 32:1989;313-316.
10. Chauhan R.P., Woodley J.M. Increasing the productivity of bioconversion processes. Chem. Tech. 27:1997;26-30.
11. Lye G.J., Woodley J.M. Application of in-situ product removal techniques to biocatalytic processes. Trends Biotechnol. 17:1999;395-402.