Graft thrombosis in hDAF-transgenic pig hearts transplanted into rhesus monkeys [1]

Xenotransplantation

Volumn 10, Issue 2, 2003, Pages 185-186

  Lam, Tuan T ^a   Borie, Dominique ^a   Masek, Marilyn ^a   Berry, Gerald ^a   Larson, Michael ^a   Morris, Randall E ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT RECEPTOR; DECAY ACCELERATING FACTOR; ERYTHROCYTE ANTIBODY; GAS 914; GLYCOCONJUGATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SOLUBLE COMPLEMENT RECEPTOR TYPE 10; STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; COMPLEMENT ACTIVATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRAFT THROMBOSIS; HEART TRANSPLANTATION; HEMOLYSIS; HYPERACUTE GRAFT REJECTION; LETTER; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SWINE; THROMBOSIS; TRANSGENIC ANIMAL; XENOTRANSPLANTATION; ANIMAL; GENETICS; GRAFT SURVIVAL; HUMAN; MACACA; POSTOPERATIVE COMPLICATION; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD55; GRAFT SURVIVAL; HUMANS; MACACA MULATTA; POSTOPERATIVE COMPLICATIONS; SWINE; THROMBOSIS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0042367679     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3089.2003.02100.x     Document Type: Letter

References (3)

1. LAM T, HAUSEN B, HOOK L et al. High levels of anti-pig hemolytic antibodies are associated with hyperacute rejection of hDAF-transgenic pig cardiac and renal xenografts in cynomolgus monkeys. Xenotransplantation 2001; 8 (Suppl. 1): 86.
2. SCHUURMAN HJ, PINO-CHAVEZ G, PHILLIPS MJ, THOMAS L, WHITE DJG, COZZI E. Incidence of hyperacute rejection in pig-to-primate transplantation using organs from hDAF-transgenic donors. Transplantation 2002; 73: 1146.
3. LAM T, HAUSEN B, HIGGINS J et al. The αGal polymer GAS914 depletes anti-αGal antibodies and prevents hyperacute rejection of hDAF-transgenic pig cardiac and renal xenografts in cynomolgus monkeys. Xenotransplantation 2001; 8 (Suppl. 1): 77.