Dynamics of isoelectric precipitation of casein using sulfuric acid

AIChE Journal

Volumn 49, Issue 8, 2003, Pages 2211-2223

  Hofland, G W ^a   Berkhoff, M R ^a   Witkamp, G J ^a   Van der Wielen, L A M ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MIXING; PH EFFECTS; PRECIPITATION (CHEMICAL); SULFURIC ACID;

SKIM MILK;

CASEIN;

MINERAL; SULFURIC ACID;

ACID; PRECIPITATION;

ACID PRECIPITATION; AGING; ARTICLE; DYNAMICS; ISOELECTRIC POINT; MILK; PARTICLE SIZE; PH; PROTEIN AGGREGATION; PROTEIN DEGRADATION; TEMPERATURE; TIME;

EID: 0042354588     PISSN: 00011541     EISSN: None     Source Type: Journal    
DOI: 10.1002/aic.690490828     Document Type: Article

References (36)

1. Bell, D. J., M. Hoare, and P. Dunnill, "The Formation of Protein Precipitates and Their Centrifugal Recovery," Adv. Biochem. Eng. Biotechnol., 26, 1 (1983).
2. Bhaskar, G. V., O. H. Campanella, and P. A. Munro, "Effect of Agitation on the Coagulation Time of Mineral Acid Casein Curd: Application of Smoluchowski's Orthokinetic Aggregation Theory," Chem. Eng. Sci., 4075 (1993).
3. Bird, R. B., W. E. Stewart, and E. N. Lightfoot, Transport Phenomena, Wiley, New York (1960)
4. Bringe, N. A., and J. E. Kinsella, "Acidic Coagulation of Casein Micelles: Mechanisms Inferred from Spectrophotometric Studies," J. Dairy Res., 57, 365 (1990).
5. Bringe, N. A., and J. E. Kinsella, "Effects of Cations and Anions on the Rate of the Acidic Coagulation of Casein Micelles: the Possible Roles of Different Forces," J. Dairy Res., 58, 195 (1991).
6. Brown, D. L., and C. E. Glatz, "Aggregate Breakage in Protein Precipitation," Chem. Eng. Sci., 42, 1831 (1987)
7. Camp, T. R., and P. C. Stein, "Velocity Gradients and Internal Work in Fluid Motion," J. Boston Soc. Civil Eng., 30, 219 (1943).
8. Cariç, M., Concentrated and Dried Dairy Products, VCH, New York (1994).
9. Dalgleish, D. G., and A. J. R. Law, "pH-Induced Dissociation of Bovine Casein Micelles," J. Dairy Res., 56, 727 (1989).
10. DeKruif, C. G., "Supra-aggregates of Casein Micelles as a Prelude to Coagulation." J. Dairy Sci., 81, 3019 (1998).
11. 2," Ind. Eng. Chem. Res., 38, 4919 (1999).
12. Holt, C., D. G. Dalgleish, and R. Jenness, "Calculation of the Ion Equilibria in Milk Diffusate and Comparison with Experiment," Anal. Biochem., 113, 154 (1981).
13. Jablonka, M. S., and P. A. Munro, "Particle Size Distribution and Calcium Content of Batch-Precipitated Acid Casein Curd: Effect of Precipitation Temperature and pH,"J. Dairy Res., 52, 419 (1985).
14. Jablonka, M. S., and P. A. Munro, "Effect of Precipitation Temperature and pH on the Mechanical Strength of Batch Precipitated Acid Casein Curd," J. Dairy Res., 53, 69 (1986).
15. Jablonka, M. S., and P. A. Munro, "Effect of Temperature and pH on the Continuous Pilot-Scale Precipitation of Acid Casein Curd," N. Z. J. Dairy Sci. Technol., 21, 111 (1986b).
16. Jablonka, M. S., and P. A. Munro, "Mechanical Properties of Lactic, Mineral Acid and Rennet Casein Curds from Commercial Plants," N. Z. J. Dairy Sci. Technol., 22, 67 (1987).
17. Jablonka, M. S., P. A. Munro, and G. G. Duffy, "Use of Light Scattering Techniques to Study the Kinetics of Precipitation of Mineral Acid Casein from Skim Milk," J. Dairy Res., 55, 179 (1988).
18. Janssen, L. P. B. M., and M. M. C. G. Warmoeskerken, Transport Phenomena Data Companion, Edward Arnold/DUM, Delft, The Netherlands (1987).
19. Kim, B. Y., and J. E. Kinsella, "Effect of Temperature and pH on the Coagulation of Casein," Milchwissenschaft, 44, 622 (1989).
20. Le Graët, Y., and F. Gaucheron, "pH-Induced Solubilization of Minerals from Casein Micelles: Influence of Casein Concentration and Ionic Strength," J. Dairy Res., 66, 215 (1999).
21. O'Meara, G. M., and P. A. Munro, "The Precipitation and Shrinkage of Acid Casein Curd: A Preliminary Study," N. Z. J. Dairy Sci. Technol., 17, 147 (1982).
22. Nelson, C. D., and C. E. Glatz, "Primary Particle Formation in Protein Precipitation," Biotechnol. Bioeng., 27, 1435 (1985).
23. Pearce, K. N., R. J. Johnstone, and A. J. Maccoll, "Computer Simulation of Continuous Counter-Current Washing of Casein Curd," N. Z. J. Dairy Sci. Technol., 22, 49 (1987).
24. Smit, D. J., M. J. Hounslow, and W. R. Paterson, "Aggregation and Gelation - I. Analytical Solutions for cst and Batch Operation," Chem. Eng. Sci., 49, 1025 (1994).
25. Söhnel, O., and J. Garside, Precipitation; Basic Principles and Industrial Applications, Butterworth-Heinemann, Oxford (1992).
26. Southward, C. R., and N. J. Walker, "The Manufacture and Industrial Use of Casein," N. Z. J. Dairy Sci. Technol, 15, 201 (1980).
27. Stryer, L., Biochemistry, 3rd ed., Freeman, New York (1988).
28. Teo, C. T., P. A. Munro, and H. Singh, "Effects of pH and Temperature on the Water-Holding Capacity of Casein Curds and Whey Protein Gels," J. Dairy Res., 6, 83 (1996a).
29. Teo, C. T., P. A. Munro, and H. Singh, "Reversibility of Shrinkage of Mineral Acid Casein Curd as a Function of Ionic Strength, pH and Temperature," J. Dairy Res., 63, 555 (1996b).
30. Thoenes, D., Chemical Reactor Development; from Laboratoty Synthesis to Industrial Production, Kluwer, Dordrecht, The Netherlands (1994).
31. Van Dijk, H. J. M., "The Properties of Casein Micelles. 2. Formation and Degradation of the Micellar Calcium Phosphate," Neth. Milk Dairy J., 44, 111 (1990).
32. van Leeuwen, M. L. J., O. S. L. Bruinsma, and G. M. van Rosmalen, "Influence of Mixing on the Product Quality in Precipitation," Chem. Eng. Sci., 51, 2595 (1996).
33. Vanni, M., "Approximate Population Balance Equations for Aggregation-Breakage Process," J. Colloid Interface Sci., 221, 143 (2000).
34. Vonk, P., Diffusion of Large Molecules in Porous Structures, PhD Diss., Univ. of Groningen, Groningen, The Netherlands (1994).
35. Walstra, P., "On the Stability of Casein Micelles," J. Dairy Sci., 73, 1965 (1990).
36. Wilcox, W. R., S. Russo, and S. H. Bauer, "Cluster Size Distribution from Homogeneous Condensation. A Stochastic Model," J. Phys. Chem., 83, 897 (1979).