Crystal structure of the intrinsically flexible addiction antidote MazE

Journal of Biological Chemistry

Volumn 278, Issue 30, 2003, Pages 28252-28257

  Loris, Remy ^a   Marianovsky, Irina ^b   Lah, Jurij ^a,c   Laeremans, Toon ^a,d   Engelberg Kulka, Hanna ^b   Glaser, Gad ^b   Muyldermans, Serge ^a   Wyns, Lode ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b HEBREW UNIVERSITY   (Israel)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

^d ABLYNX NV   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; DNA; HYDROPHOBICITY; MONOMERS; POLYPEPTIDES;

PROTEIN DOMAIN;

BIOCHEMISTRY;

ANTIDOTE; PROTEIN MAZE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; CAMEL; CRYSTAL STRUCTURE; CRYSTALLIZATION; DNA BINDING MOTIF; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CAMELS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

CAMELIDAE; CAMELUS DROMEDARIUS;

EID: 0042346293     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302336200     Document Type: Article

References (56)

1. Jensen, R. B., and Gerdes, K. (1995) Mol. Microbiol. 17, 205-210
2. Yarmolinsky, M. B. (1995) Science 267, 836-837
3. Couturier, M., Bahassi, E. M., and Van Melderen, L. (1998) Trends Microbiol. 6, 269-275
4. Engelberg-Kulka, H., and Glaser, G. (1999) Annu. Rev. Microbiol. 53, 43-70
5. Hiraga, S. (1992) Annu. Rev. Biochem. 61, 283-306
6. Williams, D. R., and Thomas, C. M. (1992) J. Gen. Microbiol. 138, 1-16
7. Aizenman, E., Engelberg-Kulka, H., and Glaser, G. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 6059-6063
8. Gotfredsen, M., and Gerdes, K. (1998) Mol. Microbiol. 29, 1065-1076
9. Masuda, Y., K. Miyakawa, Y. Nishimura, Y. Nishimura, and Ohtsubo, E. (1993) J. Bacteriol. 175, 6850-6856
10. Masuda, Y., and Ohtsubo, E. (1994) J. Bacteriol. 176, 5861-5863
11. Metzger, S., Dror, I. B., Aizenman, E., Schreiber, G., Toone, M., Friesen, J. D., Cashel, M., and Glaser, G. (1988) J. Biol. Chem. 263, 15699-15704
12. Engelberg-Kulka, H., Reches, M., Narasimhan, S., Schoulaker-Schwarz, R., Klemes, Y., Aizenman, E., and Glaser, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15481-15486
13. Marianovsky, I., Aizenman, E., Engelberg-Kulka, H., and Glaser, G. (2001) J. Biol. Chem. 276, 5975-5984
14. Sat, B., Hazan, R., Fisher, T., Khaner, H., Glaser, G., and Engelberg-Kulka, H. (2001) J. Bacteriol. 183, 2041-2045
15. Hazan, R., Sat, B. Reches, M., and Engelberg-Kulka, H. (2001) J. Bacteriol. 183, 2046-2050
16. Engelberg-Kulka, H., Sat, B., and Hazan, H. (2001) ASM News, in press
17. Bravo, A., de Torrontegui, G., and Diaz, R. (1987) Mol. Gen. Genet. 210, 101-110
18. Santos-Sierra, S., Giraldo, R., and Diaz-Orejas, R. (1997) FEMS Microbiol. Lett. 152, 51-56
19. Ruiz-Echevarria, M. J., Gimenez-Gallego, G., Sabariegos-Jarego, R., and Diaz-Orejas, R. (1995) J. Mol. Biol. 247, 568-577
20. Loris, R., Dao-Thi, M.-H., Bahassi, E. M., Van Melderen, L., Poortmans, F., Liddington, R., Couturier, M., and Wyns, L. (1999) J. Mol. Biol. 285, 1667-1677
21. Hargreaves, D., Santos-Sierra, S., Giraldo, R., Sabariegos-Jareno, R., de la Cueva-Mendez, G., Boelens, R., Diaz-Orejas, R., and Rafferty, J. B. (2002) Structure 10, 1425-1433
22. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene 77, 51-59
23. Lauwereys, M., Arbabi Ghahroudi, M., Desmyter, A., Kinne, J., Holzer, W., De Genst, E., Wyns, L., and Muyldermans, S. (1998) EMBO J. 17, 3512-3520
24. Arbabi Ghahroudi, M., Desmyter, A., Wyns, L., Hamers, R., and Muyldermans, S. (1997) FEBS Lett. 414, 521-526
25. Navaza, J. (1994) Acta Crystallogr Sect. A 50, 157-163
26. Decanniere, K., Desmyter, A., Lauwereys, M., Ghahroudi, M. A., Muyldermans, S., and Wyns, L. (1999) Struct. Fold. Des. 7, 361-370
27. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
28. Perrakis, A., Harkiolaki, M., Wilson, K. S., and Lamzin, V. S. (2001) Acta Crystallogr. Sect. D Biol. Crystallogr. 57, 1445-1450
29. Roussel, A., and Cambillau, C. (1989) Silicon Graphic Geometry Partners' Directory, pp. 71-78, Silicon Graphics, Mountain View, CA
30. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
31. Hutchinson, E. G., and Thornton, J. M. (1996) Protein Sci. 5, 212-220
32. Deleted in proof
33. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410
34. Bairoch, A., and Apweiler, R. (2000) Nucleic Acids Res. 28, 45-48
35. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680
36. Miyata, T., Miyazawa, S., and Yashunaga, T. (1979) J. Mol. Evol. 12, 219-236
37. Armon, A., Graur, D., and Ben-Tal, N. (2001) J. Mol. Biol. 307, 447-463
38. Wright, P. E., and Dyson, H. J. (1999) J. Mol. Biol. 293, 321-333
39. Hunte, C., and Michel, H. (2002) Curr. Opin. Struct. Biol. 12, 503-508
40. Oberer, M., Zangger, K., Prytulla, S., and Keller, W. (2002) Biochem. J. 361, 41-47
41. Dao-Thi, M.-H., Messens, J., Wyns, L., and Backmann, J. (2000) J. Mol. Biol. 299, 1373-8613
42. Gazit, E., and Sauer, R. T. (1999) J. Biol. Chem. 274, 2652-2657
43. Oberer, M., Lindner, H., Glatter, O., Kratky, C., and Keller, W. (1999) Biol. Chem. 380, 1413-1420
44. Lah, J., Marianowsky, I., Glaser, G., Engelberg-Kulka, H., Kinne, J., Wyns, L., and Loris, R. (2003) J. Biol. Chem. 278, 14101-14111
45. Mittenhuber, G. (1999) J. Mol. Microbiol. Biotechnol. 1, 295-302
46. Tsuchimoto, S., Ohtsubo, H., and Ohtsubo, E. (1988) J. Bacteriol. 170, 1461-1466
47. Santos-Sierra, S., Pardo-Abarrio, C., Giraldo, R., and Diaz-Orejas, R. (2002) FEMS Microbiol. Lett. 206, 115-119
48. Tam, J. E., and Kline, B. C. (1989) Mol. Gen. Genet. 219, 26-32
49. Roberts, R. C., Spangler, C., and Helinski, D. R. (1993) J. Biol. Chem. 268, 27109-27117
50. Magnuson, R., and Yarmolinsky, M. B. (1998) J. Bacteriol. 180, 6342-6351
51. Ruiz-Echevarria, M. J., Berzal-Herranz, A., Gerdes, K., and Diaz-Orejas, R. (1991) Mol. Microbiol. 5, 2685-2693
52. Dao-Thi, M.-H., Charlier, D., Loris, R., Maes, D., Messens, J., Wyns, L., and Backmann, J. (2002) J. Biol. Chem. 277, 3733-3742
53. Afif, H., Allali, N., Couturier, M., and Van Melderen, L. (2002) Mol. Microbiol. 41, 73-82
54. Kamada, K., Hanaoka, F., and Burley, S. K. (2003) Mol. Cell. 11, 875-884
55. Van Melderen, L., Dao-Thi, M.-H., Lecchi, P., Gottesman, S., Couturier, M., and Maurizi, M. R. (1996) J. Biol. Chem. 271, 27730-27738
56. Lenherr, H., and Yarmolinsky, M. B. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3274-3277