Effects of increased muscle mass on bone in male mice overexpressing IGF-I in skeletal muscles

Calcified Tissue International

Volumn 73, Issue 2, 2003, Pages 196-201

  Banu, J ^a   Wang, L ^a   Kalu, D N ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Bone; IGF I overexpression; Mice; Muscle mass; pQCT

Indexed keywords

SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE MASS; BONE MINERAL; BONE STRESS; CANCELLOUS BONE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICAL BONE; DENSITOMETRY; DIAPHYSIS; FEMUR; HETEROZYGOTE; MALE; METAPHYSIS; MOUSE; MUSCLE MASS; NONHUMAN; PARAMETER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; THICKNESS; TIBIA; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; BONE AND BONES; BONE DENSITY; DENSITOMETRY, X-RAY; FEMUR; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; TIBIA;

EID: 0042337345     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-002-1072-z     Document Type: Article

References (16)

1. Frost HM (1987) Bone 'mass' and the 'mechanostat'. Anat Rec 219:1-9
2. Burr DB (1997) Muscle strength, bone mass, and age related bone loss. J Bone Miner Res 12:1547-1551
3. Frost HM (1997) On our age-related bone loss: insights from a new paradigm. J Bone Miner Res 12:1539-1546
4. Frost HM, Ferretti JL, Jee WSS (1998) Perspectives: some roles of mechanical usage, muscle strength, and the mechanostat in skeletal physiology, disease, and research. Calcif Tissue Int 62:1-7
5. Lanyon LE (1996) Using functional loading to influence bone mass and architecture: objectives, mechanisms, and relationship with estrogen of the mechanically adaptive process in bone. Bone 18(suppl):37-43
6. Frost HM (1999) Why do bone strength and "mass" in aging adults become unresponsive to vigorous exercise? Insights of the Utah paradigm. J Bone Miner Met 17:90-97
7. Gutin B, Kasper MJ (1992) Can vigorous exercise play a role in osteoporosis prevention? A review. Osteoporosis Int 2:55-69
8. Kannus P, Sievanen H, Vuori I (1996) Physical loading, exercise, and bone. Bone 18(suppl):1-3
9. Coleman ME, DeMayo F, Yin KC et al. (1995) Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. JBC 270:12109-12116
10. Ausubel FM, Brent R, Kingston RE et al. (1987) Current protocols in molecular biology. John Wiley Sons, New York pp 2.2 and 4.10
11. Kalu DN, Arjmandi BH, Birnbaum RS, Liu CC, Salih MA (1994) Effects of ovariectomy and estrogen on serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3. Bone Miner 25:135-148
12. Schiessel H, Willnecker J (1999) Muscle cross-sectional area and bone cross-sectional area in the human lower leg measured with peripheral computed tomography. In: GP Lyritis (ed), Musculoskeletal interactions, vol 2, Hylonome, pp 47-52
13. Daughaday WH, Rotwein P (1989) Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structure, serum, and tissue concentrations. Endocr Rev 10:68-91
14. Sara VR, Hall K (1990) Insulin-like growth factors and their binding proteins. Physiol Rev 70:591-614
15. Cohick W, Clemmons DR (1993) The insulin-like growth factors. Ann Rev Physiol 55:131-153
16. Rosen CJ, Pollack M (1999) Circulating IGF-I: new perspectives for a new century. TEM 10:136-141