Evaluation of 99mTc-HMPAO leukocyte scintigraphy in the investigation of pediatric inflammatory bowel disease

Journal of Pediatrics

Volumn 143, Issue 1, 2003, Pages 48-53

  Grahnquist, Lena ^a   Chapman, Stephen C ^a   Hvidsten, Sasha ^a   Murphy, M Stephen ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADOLESCENT; ARTICLE; BARIUM MEAL; CHILD; CLINICAL TRIAL; COLONOSCOPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROHN DISEASE; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; ENDOSCOPY; FEMALE; HOSPITAL DEPARTMENT; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERMETHOD COMPARISON; LABORATORY DIAGNOSIS; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; PRIORITY JOURNAL; SCINTIGRAPHY; SCREENING TEST; SENSITIVITY AND SPECIFICITY; ULCERATIVE COLITIS; COLON; DUODENITIS; ENTERITIS; EVALUATION; GASTRITIS; INTESTINE MUCOSA; METHODOLOGY; PATHOLOGY; PREDICTION AND FORECASTING; PRESCHOOL CHILD; SCINTISCANNING;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; COLITIS, ULCERATIVE; COLON; COLONOSCOPY; CROHN DISEASE; DUODENITIS; ENTERITIS; FEMALE; GASTRITIS; HUMANS; INTESTINAL MUCOSA; LEUKOCYTES; MALE; PREDICTIVE VALUE OF TESTS; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M EXAMETAZIME;

EID: 0042331725     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3476(03)00280-4     Document Type: Article

References (31)

1. Shields RA, Lawson RS. Effective dose equivalent. Nucl Med Commun 1987;8:851-5.
2. Murphy MS. Sedation for invasive procedures in paediatrics [see comments]. Arch Dis Child 1997;77:281-4.
3. Spray C, Debelle GD, Murphy MS. Current diagnosis, management, and morbidity in paediatric inflammatory bowel disease. Acta Paediatr 2000.
4. Giaffer MH. Labelled leucocyte scintigraphy in inflammatory bowel disease: clinical applications. Gut 1996;38:1-5.
5. 99Tcm HMPAO leucocyte scintigraphy distinguish between Crohn's disease and ulcerative colitis?. Br J Radiol 1994;67:472-7.
6. Charron M, del Rosario JF, Kocoshis S. Use of technetium-tagged white blood cells in patients with Crohn's disease and ulcerative colitis: is differential diagnosis possible? Pediatr Radiol 1998;28:871-7.
7. Administration of Radioactive Substances Advisory Committee. Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources: ARSAC Support Unit, Oxford, United Kingdom; 19884th ed..
8. 99mhexamethyl propylene amine oxine as leukocyte label. Gastroenterology 1988;95:1287-93.
9. Henderson AR. Assessing test accuracy and its clinical consequences: a primer for receiver operating characteristic curve analysis. Ann Clin Biochem 1993;30:521-39.
10. Harper R, Reeves B. Reporting of precision of estimates for diagnostic accuracy: a review. BMJ 1999;318:1322-3.
11. Kennan N, Hayward M. Tc-HMPAO-labelled white cell scintigraphy in Crohn's disease of the small bowel. Clin Radiol 1992;45:331-4.
12. Almer S, Franzen L, Peters AM, et al. Do technetium-99m hexamethylpropylene amine oxime-labeled leukocytes truly reflect the mucosal inflammation in patients with ulcerative colitis? Scand J Gastroenterol 1992;27:1031-8.
13. 99mTc-HMPAO leukocyte scan: an alternative to radiology and endoscopy in evaluating the extent and the activity of inflammatory bowel disease. J Nucl Biol Med 1991;35:82-7.
14. Lantto E, Jarvi K, Krekela I, et al. Technetium-99m hexamethyl propylene amine oxine leucocytes in the assessment of disease activity in inflammatory bowel disease. Eur J Nucl Med 1992;19:14-8.
15. Papos M, Nagy F, Lang J, Csernay L Technetium-99m hexamethyl-propylene amine oxime labelled leucocyte scintigraphy in ulcerative colitis and Crohn's disease. Eur J Nucl Med 1993;20:766-9.
16. Vilien M, Nielsen SL, Jorgensen M, et al. Leucocyte scintigraphy to localize inflammatory activity in ulcerative colitis and Crohn's disease. Scand J Gastroenterol 1992;27:582-6.
17. Sciarretta G, Furno A, Mazzoni M, Basile C, Malaguti P. Technetium-99m hexamethyl propylene amine oxime granulocyte scintigraphy in Crohn's disease: diagnostic and clinical relevance [see comments]. Gut 1993;34:1364-9.
18. 99mTc white blood cells. Radiology 1999;212:507-13.
19. 99mTc-white cell scanning to detect gut inflammation in children with inflammatory bowel diseases or spondyloarthropathies. Clin Exp Rheumatol 1998;16:327-34.
20. Papos M, Varkonyi A, Lang J, et al. HM-PAO-labeled leukocyte scintigraphy in pediatric patients with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1996;23:547-52.
21. Jobling JC, Lindley KJ, Yousef Y, Gordon I, Milla PJ. Investigating inflammatory bowel disease-white cell scanning, radiology, and colonoscopy. Arch Dis Child 1996;74:22-6.
22. Del Rosario MA, Fitzgerald JF, Siddiqui AR, Chong SK, Croffie JM, Gupta SK. Clinical applications of technetium Tc-99m hexamethyl propylene amine oxime leukocyte scan in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1999;28:63-70.
23. Shah DB, Cosgrove M, Rees JI, Jenkins HR. The technetium white cell scan as an initial imaging investigation for evaluating suspected childhood inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1997;25:524-8.
24. Charron M, Orenstein SR, Bhargava S. Detection of inflammatory-bowel disease in pediatric patients with technetium-99m-HMPAO-labeled leukocytes [see comments]. J Nucl Med 1994;35:451-5.
25. Jewell FM, Davies A, Sandhu B, Duncan A, Grier D. Technetium-99m-HMPAO labelled leucocytes in the detection and monitoring of inflammatory bowel disease in children. Br J Radiol 1996;69:508-14.
26. Charron M, Di Lorenzo C, Kocoshis S. Gastric and small bowel Crohn's disease assessed with leukocytes-Tc(99m) scintigraphy. Pediatr Surg Int 1999;15:500-4.
27. Charron M, Del Rosario F, Kocoshis S. Assessment of terminal ileal and colonic inflammation in Crohn's disease with 99mTc-WBC. Acta Paediatr 1999;88:193-8.
28. Haggitt RC, Meissner WA. Crohn's disease of the upper gastrointestinal tract. Am J Clin Pathol 1973;59:613-22.
29. Griffiths AM, Alemayehu E, Sherman P. Clinical features of gastroduodenal Crohn's disease in adolescents. J Pediatr Gastroenterol Nutr 1989;8:166-71.
30. Halligan S, Nicholls S, Bartram CI, Walker-Smith JA. The distribution of small bowel Crohn's disease in children compared to adults. Clin Radiol 1994;49:314-6.
31. Oberhuber G, Puspok A, Oesterreicher C, et al. Focally enhanced gastritis: a frequent type of gastritis in patients with Crohn's disease [comment]. Gastroenterology 1997;112:698-706.