Static and dynamic disorder in protein folding: Experiments with single Maltoporin channels

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 5110, Issue , 2003, Pages 50-56

  Kullman, Lisen ^a,b   Winterhalter, Mathias ^c   Bezrukov, Sergey M ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

^c INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Channel reconstitution; Enzymatic reactions; Ionic conductance; Lipid bilayers; Single molecules

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; HYDROGEN BONDS; LIPIDS; MOLECULES; SUGARS;

CHANNEL RECONSTITUTION; ENZYMATIC REACTIONS; IONIC CONDUCTANCE; LIPID BILAYERS; PROTEIN FOLDING; SINGLE MALTOPORIN CHANNELS;

PROTEINS;

EID: 0042326269     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.500833     Document Type: Conference Paper

References (21)

1. H. Frauenfelder, S.G. Sligar and P.G. Wolynes, "The energy landscapes and motions of proteins", Science, 254, 1598-1603, 1991.
2. H. Frauenfelder and D.T. Leeson, "The energy landscape in non-biological and biological molecules", Nat. Struct. Biol., 5, 757-759, 1998.
3. X.S. Xie, "Single-molecule approach to dispersed kinetics and dynamic disorder: Probing conformational fluctuation and enzymatic dynamics", J. Chem. Phys., 117, 11024-11032, 2002.
4. R. Zwanzig, "Rate processes with dynamic disorder", Acc. Chem. Res., 23, 148-152 1990.
5. S. Weiss, "Fluorescence spectroscopy of single biomolecules", Science, 283, 1676-1683, 1999.
6. H. Nikaido and M. Vaara, "Molecular basis of bacterial outer membrane permeability", Microbiol. Rev., 49, 1-32, 1985.
7. R. Benz, "Structure and function of porins from gram-negative bacteria", Ann. Rev. Microbiol., 42, 359-393, 1988.
8. T. Schirmer, T.A. Keller, Y.-F. Wang and J.P. Rosenbusch, "Structural basis for sugar translocation through maltoporin channels at 3.1 Å resolution", Science, 267, 512-514, 1995.
9. R. Dutzler, Y.-F. Wang, P.J. Rizkallah, J.P. Rosenbusch and T. Schirmer, "Crystal structures of various maltooliosaccharides bound to maltoporin reveal a specific sugar translocation pathway", Structure, 4, 127-134, 1995.
10. G. Schindler and J.P. Rosenbusch, "Matrix protein from Escherichia coli outer membranes forms voltage-controlled channels in lipid bilayers", Proc. Natl. Acad. Sci. USA, 75, 3751-3755, 1978.
11. R. Benz, A. Schmid, T. Nakae and G.H. Vos-Scheperkeuter, "Pore formation by LamB of Escherichia coli in lipid bilayer membranes", J. Bact., 165, 978-986, 1986.
12. B. Dargent, J. Rosenbusch and F. Pattus, "Selectivity for maltose and maltodextrins of maltoporin, a pore-forming protein of E. coli outer membrane", FEBS Letters, 220, 136-142, 1987.
13. T. Ferenci, M. Schwentorat, S. Ullrich and J. Vilmart, "Lambda receptor in the outer membrane of Escherichia coli as a binding protein for maltodextrins and starch polysaccharides", J. Bacteriol., 142, 521-526, 1980.
14. M. Luckey and H. Nikaido, "Specificity of diffusion channels produced by λ-phage receptor protein of Escherichia coli", Proc. Natl. Acad. Sci. USA, 77, 167-171, 1980.
15. R. Benz, A. Schmid and G.H. Vos-Scheperkeuter, "Mechanism of sugar transport through the sugar-specific LamB channel of Escherichia coli outer membrane", J. Membrane Biol., 100, 21-29, 1987.
16. S. Nekolla, C. Andersen and R. Benz, "Noise analysis of ion current through the open and the sugar-induced closed state of the LamB channel of Escherichia coli outer membrane: Evaluation of the sugar binding kinetics to the channel interior", Biophys. J., 66, 1388-1397, 1994.
17. C. Andersen, M. Jordy and R. Benz, "Evaluation of the rate constants of sugar transport through maltoporin (LamB) of Escherichia coli from the sugar-induced current noise", J. Gen. Physiol., 105, 385-401, 1995.
18. S.M. Bezrukov, L. Kullman and M. Winterhalter, "Probing sugar translocation through maltoporin at the single channel level", FEBS Letters, 476, 224-228, 2000.
19. L. Kullman, M. Winterhalter and S.M. Bezrukov, "Transport of maltodextrins through maltoporin: A single-channel study", Biophys. J., 82, 803-812, 2002.
20. S.M. Bezrukov and I. Vodyanoy, "Probing alamethicin channels with water-soluble polymers. Effect on conductance of channel states", Biophys. J., 64, 16-25, 1993.
21. S.M. Bezrukov and M. Winterhalter, "Examining noise sources at the single-molecule level: 1/f noise of an open maltoporin channel", Phys. Rev. Lett., 85, 202-205, 2000.