The prognostic significance of serial myoglobin, troponin I, and creatine kinase-MB measurements in patients evaluated in the emergency department for acute coronary syndrome

Annals of Emergency Medicine

Volumn 42, Issue 3, 2003, Pages 343-350

  McCord, James ^a,b   Nowak, Richard M ^a   Hudson, Michael P ^a   McCullough, Peter A ^a   Tomlanovich, Michael C ^a   Jacobsen, Gordon ^a   Tokarski, Glenn ^a   Khoury, Nabil ^a   Weaver, W Douglas ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

^b Henry Ford Heart/Vascular Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE MB; MYOGLOBIN; TROPONIN I;

ADULT; AGED; ARTICLE; DISEASE MARKER; EMERGENCY WARD; FEMALE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; PRIORITY JOURNAL; PROGNOSIS; SENSITIVITY AND SPECIFICITY;

EID: 0042324764     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-0644(03)00411-6     Document Type: Article

References (24)

1. Lee KL, Pryor DB, Harrel PE, et al. Predicting outcome in coronary disease: statistical models versus expert clinicians, Am J Med. 1986;80:533-560.
2. Karlson BW, Herlitz J, Wicklund O, et al. Early prediction of acute myocardial infarction from clinical history, examination and electrocardiogram in the emergency room. Am J Cardiol. 1991;68:171-175.
3. Lee T, Juarez G, Cook E, et al. Ruling out acute myocardial infarction: a prospective multi-center validation of a 12-hour strategy for patients at low risk. N Engl J Med. 1991;324:1239-7246.
4. Hamm CW, Goldman BU, Heeschen C, et al. Emergency room triage of patients with chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med. 1997;337:1648-1653.
5. Newby LK, Storrow AB, Gibler WB, et al. Bedside multimarker testing for risk stratification in chest pain units. Circulation. 2001;103:1832-1837.
6. Hillis GS, Zhao N, Taggart P, et al. Utility of cardiac troponin I, creatine kinase-MB, myosin light chains 1, and myoglobin in the early in-hospital triage of "high risk" patients with chest pain. Heart. 1999;82:614-620.
7. Newby LK, Christensen RH, Ohman EM, et al. Value of serial tropenin T measures for early and late risk stratification in patients with acute coronary syndromes. Circulation. 1998;98:1853-1859.
8. Hedges JR, Swanson JR, Heeter C, et al. Prospective assessment of presenting serum markers for cardiac risk stratification. Acad Emerg Med. 1996;3:27-33.
9. Newby LK, Kaplan AL, Granger BB, et al. Comparison of cardiac troponin T versus creatinine kinase-MB for risk stratification in a chest pain evaluation unit. Am J Cardiol. 2000;85:801-805.
10. Alexander JH, Sparapani RA, Hahaffey KW, et al. Association between minor elevations of creatine kinase-MB level and mortality in patients with acute coronary syndrome without ST-segment elevation. JAMA. 2000;283:347-353.
11. Jurlander B, Clemmensen P, Wagner GS, et al. Very early diagnosis and risk stratification of patients admitted with suspected acute myocardial infarction by the combined elevation of a single serum value of cardiac troponin T, myoglobin, and creatine kinase-MB. Eur Heart J. 2000;21:382-389.
12. de Winter RJ, Koster RW, Schotveld JH, et al. Prognostic value of troponin T, myoglobin, and CK-MB mass in patients presenting with chest pain without acute myocardial infarction. Heart. 1996;75:235-239.
13. Sonel A, Sassen BM, Fineberg N, et al. Prospective study correlating fibrinopeptide A, troponin I, myoglobin, and myosin light chain levels with early and late ischemic events in consecutive patients presenting to the emergency department with chest pain. Circulation. 2000;102:1107-1113.
14. Green GB, Skarbek-Borowski GW, Chan DW, et al. Myoglobin for early risk stratification of emergency department patients with possible myocardial ischemia. Acad Emerg Med. 2000;7:626-636.
15. Stork TV, Wu AH, Muller-Bardorff M, et al. Diagnostic and prognostic role of myoglobin in patients with suspected acute coronary syndrome. Am J Cardiol. 2000;86:1371-1374.
16. McCord J, Nowak RM, McCullough PA, et al. Ninety-minute exclusion of acute myocardial infarction by use of point-of-care testing of myoglobin and troponin I. Circulation. 2001;104:1483-1488.
17. Gibler WB, Hoekstra JW, Weaver WD, et al. A randomized trial of the effects of early cardiac serum marker availability on reperfusion therapy in patients with AMI. J Am Coll Cardiol. 2000;36:1500-1506.
18. Ngo SM, Krishnaswamy P, Morrissey R, et al. Ninety-minute accelerated critical pathway for chest pain evaluation. Am J Med. 2001;111:274-279.
19. de Lemos JA, Antman EM, Giugliano RP, et al. Very early risk stratification after thrombolytic therapy with a bedside myoglobin assay and the 12-lead electrocardiogram. Am Heart J. 2000;140:373-378.
20. de Lemos JA, Morrow DA, Gibson CM, et al. The prognostic value of serum myoglobin in patients with non-ST-segment elevation acute coronary syndromes. Results from the TIMI 11B and TACTICS-TIMI 18 studies. J Am Coll Cardiol. 2002;40:238-244.
21. Arlanti S, Brenna S, Prencipe L, et al. Myocardial necrosis in ICU patients with acute non-cardiac disease: a prospective study. Intensive Care Med. 2000;26:31-37.
22. The Joint European Society of Cardiology/American College of Cardiology Committee. Myocardial infarction redefined: a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. Eur Heart J. 2000;21:1502-1513.
23. Benamer H, Steg PG, Benessiano J, et al. Elevated cardiac troponin I predicts a high-risk angiographic anatomy of the culprit lesion in unstable angina. Am Heart J. 1999;137:815-820.
24. Jaffe AS, Ravtrilde J, Roberts R, et al. It's time for a change to a troponin standard. Circulation. 2002;102:1216-1220.