Alternatively spliced products of the human kinesin light chain 1 (KNS2) gene

Traffic

Volumn 4, Issue 8, 2003, Pages 576-580

  McCart, Amy E ^a   Mahony, Donna ^a   Rothnagel, Joseph A ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Alternative isoforms; Alternative splicing; Kinesin; Kinesin light chain; Multiple transcripts

Indexed keywords

HOLOENZYME; ISOPROTEIN; KINESIN; MESSENGER RNA; PROTEIN SUBUNIT;

3' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ARTICLE; CALCULATION; CARBOXY TERMINAL SEQUENCE; CELL TRANSPORT; EXON; GENETIC VARIABILITY; HUMAN; MICROTUBULE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION;

EID: 0042310979     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2003.00113.x     Document Type: Article

References (28)

1. Stenoien DL, Brady ST. Immunochemical analysis of kinesin light chain function. Mol Biol Cell 1997;8:675-689.
2. Vale RD. The molecular motor toolbox for intracellular transport. Cell 2003; 112:467-480.
3. Tanaka Y, Kanai Y, Okada Y, Nonaka S, Takeda S, Harada A, Hirokawa N. Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell 1998;93:1147-1158.
4. Gyoeva FK, Gelfand VI. Coalignment of vimentin intermediate filaments with microtubules depends on kinesin. Nature 1991;353:445-448.
5. Prahlad V, Yoon M, Moir RD, Vale RD, Goldman RD. Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks. J Cell Biol 1998;143:159-170.
6. Brady ST. A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 1985;317:73-75.
7. Vale RD, Reese TS, Sheetz MP. Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell 1985;42: 39-50.
8. Yang JT, Saxton WM, Stewart RJ, Raff EC, Goldstein LS. Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science 1990;249:42-47.
9. Palacios IM, Johnston D. S. Kinesin light chain-independent function of the kinesin heavy chain in cytoplasmic streaming and posterior localisation in the Drosophila oocyte. Development 2002;129:5473-5485.
10. Gindhart JG, Jr, Desai CJ, Beushausen S, Zinn K, Goldstein LS. Kinesin light chains are essential for axonal transport in Drosophila. J Cell Biol 1998;141:443-454.
11. Verhey KJ, Lizotte DL, Abramson T, Barenboim L, Schnapp BJ, Rapoport TA. Light chain-dependent regulation of kinesin's interaction with microtubules. J Cell Biol 1998;143:1053-1066.
12. Rahman A, Friedman DS, Goldstein LS. Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins. J Biol Chem 1998;273:15395-15403.
13. Diefenbach RJ, Mackay JP, Armati PJ, Cunningham AL. The C-terminal region of the stalk domain of ubiquitous human kinesin heavy chain contains the binding site for kinesin light chain. Biochemistry 1998;37:16663-16670.
14. Gindhart JG, Jr, Goldstein LS. Tetratrico peptide repeats are present in the kinesin light chain. Trends Biochem Sci 1996;21:52-53.
15. Verhey KJ, Meyer D, Deehan R, Blenis J, Schnapp BJ, Rapoport TA, Margolis B. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J Cell Biol 2001;152:959-970.
16. Wedaman KP, Knight AE, Kendrick-Jones J, Scholey JM. Sequences of sea urchin kinesin light chain isoforms. J Mol Biol 1993;231: 155-158.
17. Beushausen S, Kladakis A, Jaffe H. Kinesin light chains. identification and characterization of a family of proteins from the optic lobe of the squid Loligro pealii. DNA Cell Biol 1993;12:901-909.
18. Cyr JL, Pfister KK, Bloom GS, Slaughter CA, Brady ST. Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proc Natl Acad Sci USA 1991;88:10114-10118.
19. Fan J, Amos LA. Kinesin light chain isoforms in Caenorhabditis elegans. J Mol Biol 1994;240:507-512.
20. Khodjakov A, Lizunova EM, Minin AA, Koonce MP, Gyoeva FK. A specific light chain of kinesin associates with mitochondria in cultured cells. Mol Biol Cell 1998;9:333-343.
21. Elluru RG, Bloom GS, Brady ST. Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms. Mol Biol Cell 1995;6:21-40.
22. Pfister KK, Wagner MC, Stenoien DL, Brady ST, Bloom GS. Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. J Cell Biol 1989;108:1453-1463.
23. Matthies HJ, Miller RJ, Palfrey HC. Calmodulin binding to and cAMP-dependent phosphorylation of kinesin light chains modulate kinesin ATPase activity. J Biol Chem 1993;268:11176-11187.
24. Cabeza-Arvelaiz Y, Shih LC, Hardman N, Asselbergs F, Bilbe G, Schmitz A, White B, Siciliano MJ, Lachman LB. Cloning and genetic characterization of the human kinesin light-chain (KLC) gene. DNA Cell Biol 1993;12: 881-892.
25. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; 1989.
26. Morfini G, Szebenyi G, Elluru R, Ratner N, Brady S. T. Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J 2002;21:281-293.
27. Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 2000;28:449-459.
28. Gyoeva FK, Bybikova EM, Minin AA. An isoform of kinesin light chain specific for the Golgi complex. J Cell Sci 2000;113:2047-2054.