Itraconazole-tacrolimus drug interaction [1]

Therapeutic Drug Monitoring

Volumn 25, Issue 4, 2003, Pages 483-484

  Cervelli, Matthew J ^a   Russ, Graeme R ^a  

^a QUEEN ELIZABETH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIFUNGAL AGENT; ATORVASTATIN; BICARBONATE; CIPROFLOXACIN; CYTOCHROME P450 3A4; CYTOCHROME P450 INHIBITOR; DILTIAZEM; ERYTHROMYCIN; FAMCICLOVIR; FENTANYL; GLYCOPROTEIN P; IMMUNOSUPPRESSIVE AGENT; ITRACONAZOLE; METICILLIN; METRONIDAZOLE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; PYRROLE DERIVATIVE; RANITIDINE; TACROLIMUS; VANCOMYCIN; VERAPAMIL;

ADULT; CADAVER DONOR; CASE REPORT; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG MONITORING; DRUG WITHDRAWAL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; LETTER; LIVING DONOR; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUTH ULCER; NEPHROTOXICITY; PAIN; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; STAPHYLOCOCCUS INFECTION;

ADULT; ANTIFUNGAL AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; ITRACONAZOLE; KIDNEY TRANSPLANTATION; MALE; PANCREAS TRANSPLANTATION; TACROLIMUS; TIME FACTORS;

EID: 0042266802     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200308000-00012     Document Type: Letter

References (7)

1. Macias MO, Salvador P, Hurtado JL, et al. Tacrolimus-itraconazole interaction in a kidney transplant patient. Ann Pharmacother. 2000;34:536.
2. Capone D, Gentile A, Imperatore P, Palmiero GG, Basile V. Effects of intraconazole on tacrolimus blood concentrations in a renal transplant recipient. Ann Pharmacother. 1999;33:1123-1124.
3. Kramer MR, Merin G, Rudis E, et al. Dose adjustment and cost of itraconazole prophylaxis in lung transplant recipients receiving cyclosporin and tacrolimus (FK506). Transplant Proc. 1997;29:2657-2659.
4. Billaud EM, Guillemain R, Tacco F, et al. Evidence for a pharmacokinetic interaction between intraconazole and tacrolimus in organ transplant recipients. Br J Clin Pharmacol. 1998;46:271-274.
5. Furlan V, Parquin F, Penaud JF, et al. Interaction between tacrolimus and itraconazole in a heart-lung transplant recipient. Transplant Proc. 1998;30:187-188.
6. Albengres E, Louet HL, Tillement JP. Systemic antifungal agents, drug interactions of clinical significance. Drug Saf. 1998;18:83-97.
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