Forelimb vasodilatation induced by hypothalamic stimulation is greatly mediated with nitric oxide in anesthetized cats

Japanese Journal of Physiology

Volumn 53, Issue 2, 2003, Pages 97-103

  Komine, Hidehiko ^a   Matsukawa, Kanji ^a   Murata, Jun ^a   Tsuchimochi, Hirotsugu ^a   Shimizu, Kiyoshi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Blood flow velocity; Brachial artery; Stimulation of the hypothalamic defense area; Sympathetic cholinergic nerve; Vascular conductance

Indexed keywords

ATROPINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; BRAIN DEPTH STIMULATION; CAT; CONTROLLED STUDY; ELECTROSTIMULATION; FEMORAL ARTERY; FORELIMB; HINDLIMB; HYPOTHALAMUS; NONHUMAN; SYMPATHETIC TONE; VASODILATATION;

ANESTHESIA; ANIMALS; AORTA; ATROPINE; BLOOD FLOW VELOCITY; BLOOD PRESSURE DETERMINATION; BRACHIAL ARTERY; CARDIAC OUTPUT; CAROTID ARTERIES; CATS; DATA INTERPRETATION, STATISTICAL; ELECTRIC STIMULATION; ENZYME INHIBITORS; FEMORAL ARTERY; FORELIMB; HEART RATE; HYPOTHALAMUS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PARASYMPATHOLYTICS; RESPIRATION, ARTIFICIAL; SYMPATHETIC NERVOUS SYSTEM; TRACHEOTOMY; VASODILATION;

EID: 0042196454     PISSN: 0021521X     EISSN: None     Source Type: Journal    
DOI: 10.2170/jjphysiol.53.97     Document Type: Article

References (17)

1. Bolme P and Fuxe K: Adrenergic and cholinergic nerve terminals in skeletal muscle vessels. Acta Physiol Scand 78: 52-59, 1970
2. Burnstock G: Cholinergic and purinergic regulation of blood vessels. In: Handbook of Physiology. Section 2: The Cardiovascular System, Vol II. Vascular Smooth Muscle, ed. Bohr DF, Somlyo AP, and Sparks HV Jr, American Physiological Society, Bethesda, Maryland, pp 567-612, 1980
3. Uvnäs B: Sympathetic vasodilator system and blood flow. Physiol Rev 40 (Suppl 4): 69-76, 1960
4. Matsukawa K, Shindo T, Shirai M, and Ninomiya I: Direct observations of sympathetic cholinergic vasodilatation of skeletal muscle small arteries in the cat. J Physiol (Lond) 500: 213-225, 1997
5. Matsukawa K, Shirai M, Murata J, Tsuchimochi H, Komine H, Ninomiya I, and Shimizu K: Sympathetic cholinergic vasodilatation of skeletal muscle small arteries. Jpn J Pharmacol 88: 14-18, 2002
6. Matuskawa K, Shindo T, Shirai M, and Ninomiya I: Nitric oxide mediates cat hindlimb cholinergic vasodilation induced by stimulation of posterior hypothalamus. Jpn J Physiol 43: 473-483, 1993
7. Blair DA, Glover WE, Greenfield ADM, and Roddie IC: Excitation of cholinergic vasodilator nerves to human skeletal muscles during emotional stress. J Physiol (Lond) 148: 633-647, 1959
8. Barcroft H, Brod J, Hejl Z, Hirsjärvi EA, and Kitchin AH: The mechanism of the vasodilatation in the forearm muscle during stress (mental arithmetic). Clin Sci 19: 577-586, 1960
9. Roddie IC: Human responses to emotional stress. Ir J Med Sci 146: 395-417, 1977
10. Rusch NJ, Shepherd JT, Webb RC, and Vanhoutte PM: Different behavior of the resistance vessels of the human calf and forearm during contralateral isometric exercise, mental stress, and abnormal respiratory movements. Circ Res 48 (Suppl I): 118-130, 1981
11. Sanders JS, Mark AL, and Ferguson DW: Evidence for cholinergically mediated vasodilation at the beginning of isometric exercise in humans. Circulation 79: 815-824, 1989
12. Fuxe K and Sedvall G: The distribution of adrenergic nerve fibres to the blood vessels in skeletal muscle. Acta Physiol Scand 64: 75-86, 1965
13. Dietz NM, Rivera JM, Eggener SE, Fix RT, Warner DO, and Joyner MJ: Nitric oxide contributes to the rise in forearm blood flow during mental stress in humans. J Physiol (Lond) 480: 361-368, 1994
14. Taylor JA, Joyner MJ, Chase PB, and Seals DR: Differential control of forearm and calf vascular resistance during one-leg exercise. J Appl Physiol 67:1791-1800, 1989
15. Eklund B, Kaijser L, and Knutsson E: Blood flow in resting (contralateral) arm and leg during isometric contraction. J Physiol (Lond) 240: 111-124, 1974
16. Dietz NM, Engelke KA, Samuel TT, Fix RT, and Joyner MJ: Evidence for nitric oxide-mediated sympathetic forearm vasodilatation in humans. J Physiol (Lond) 498: 531-540, 1997
17. Toda N and Okamura T: Regulation by nitroxidergic nerve of arterial tone. News Physiol Sci 7: 148-152, 1992