Amphiphysin paraneoplastic syndrome: A delayed diagnosis of breast carcinoma

Breast Journal

Volumn 9, Issue 4, 2003, Pages 316-318

  Georgian Smith, Dianne ^a   Ellis, Georgiana K ^b   Kraft, George H ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

Amphiphysin autoimmunity; Breast cancer; Paraneoplastic syndrome

Indexed keywords

AMPHIPHYSIN; AUTOANTIBODY; TAMOXIFEN;

ADULT; AMPHIPHYSIN AUTOIMMUNITY; ARTICLE; BREAST CARCINOMA; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DYSARTHRIA; DYSTONIA; FEMALE; HUMAN; HYPESTHESIA; LAMINECTOMY; MAMMOGRAPHY; MASTECTOMY; MUSCLE SPASM; MUSCLE STIFFNESS; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PARANEOPLASTIC SYNDROME; SPINE FUSION;

BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MIDDLE AGED; NERVE TISSUE PROTEINS; PARANEOPLASTIC SYNDROMES, NERVOUS SYSTEM;

EID: 0042165920     PISSN: 1075122X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-4741.2003.09414.x     Document Type: Article

References (9)

1. Lichte B, Veh RW, Meyer HE, Kilimann MW. Amphiphysin, a novel protein associated with synaptic vesicles. EMBO J 1992;11:2521-30.
2. Folli F, Solimena M, Cofiell R, et al. Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer. N Engl J Med 1993;328:546-51.
3. Rosin L, DeCamilli P, Butler M, et al. Stiff-man syndrome in a woman with breast cancer. Neurology 1998;50:94-98.
4. Lennon VA, Manley HA, Kim K, Parisi JE, Kilimann MW, Benarroch EE. Amphiphysin autoantibodies: a paraneoplastic serological marker of breast and lung cancer-related encephalomyeloradiculoneuritides but not classical stiffman syndrome. Neurology 1997;48:A434.
5. Saiz A, Dalmau J, Butler MH, et al. Antibodies in patients with paraneoplastic neurological disorders associated with small cell lung carcinoma. J Neurol Neurosurg Psychiatry 1999;66:214-17.
6. Fathallah-Shaykh HM. Paraneoplastic neurological syndromes [editorial]. Arch Neurol 1999;56:151-52.
7. Antoine JC, Absi L, Honnorat J, et al. Antiamphiphysin antibodies are associated with various paraneoplastic neurological syndromes and tumors. Arch Neurol 1999;56:172-77.
8. David C, McPherson PS, Mundigl O, De Camilli P. A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals. Proc Natl Acad Sci 1996;93:331-35.
9. Floyd S, Husta Butler M, Cremona O, et al. Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. Mol Med 1998;4:29-39.