Long-term retention of the classically conditioned eyeblink response in rats

Behavioral Neuroscience

Volumn 117, Issue 4, 2003, Pages 871-875

  Nicholson, Daniel A ^a,b   Sweet, Jesse A ^a,b   Freeman Jr , John H ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b E11 SSH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; EXPERIMENTAL MODEL; EYELID REFLEX; LONG TERM MEMORY; MALE; MEMORY CONSOLIDATION; NERVE STIMULATION; NONHUMAN; RAT; TIME SERIES ANALYSIS; TRAINING;

ANIMALS; BLINKING; CONDITIONING, CLASSICAL; EXTINCTION, PSYCHOLOGICAL; MALE; MEMORY; MEMORY DISORDERS; MODELS, ANIMAL; RATS; RATS, LONG-EVANS;

EID: 0042165883     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.117.4.871     Document Type: Article

References (48)

1. Bailey, C. H., & Chen, M. (1989). Time course of structural changes at identified sensory neuron synapses during long-term sensitization in Aplysia. Journal of Neuroscience, 9, 1774-1780.
2. Coleman, S. R., & Gormezano, I. (1971). Classical conditioning of the rabbit's (Oryctolagus cuniculus) nictitating membrane response under symmetrical CS-US interval shifts. Journal of Comparative and Physiological Psychology, 77, 447-455.
3. Freeman, J. H., Jr., Muckler, A. S., & Nicholson, D. A. (2002). Learning-specific enhancement of mossy fiber synaptic input to the interpositus nucleus. Society for Neuroscience Abstracts, 79, 3.
4. Freeman, J. H., Jr., & Nicholson, D. A. (1999). Neuronal activity in the cerebellar interpositus and lateral pontine nuclei during inhibitory classical conditioning of the eyeblink response. Brain Research, 833, 225-233.
5. Freeman, J. H., Jr., & Nicholson, D. A. (2000). Developmental changes in eye-blink conditioning and neuronal activity in the cerebellar interpositus nucleus. Journal of Neuroscience, 20, 813-819.
6. Freeman, J. H., Jr., Nicholson, D. A., Muckler, A. S., Rabinak, C., & DiPietro, N. (2003). Ontogeny of eyeblink conditioned response timing in rats. Behavioral Neuroscience, 117, 283-291.
7. Frey, P., & Butler, C. (1977). Extinction after aversive conditioning: an associative or nonassociative process? Learning and Motivation, 8, 1-17.
8. Frey, P., & Ross, L. E. (1968). Classical conditioning of the rabbit eyelid response as a function of interstimulus interval. Journal of Comparative and Physiological Psychology, 65, 246-250.
9. Geinisman, Y., Disterhoft, J. F., Gundersen, H. J., McEchron, M. D., Persina, I. S., Power, J. M., et al. (2000). Remodeling of hippocampal synapses after hippocampus-dependent associative learning. Journal of Comparative Neurology, 417, 49-59.
10. Gormezano, I., Kehoe, E. J., & Marshall, B. S. (1983). Twenty years of classical conditioning research with the rabbit. In J. M. Sprague & A. N. Epstein (Eds.), Progress in psychobiology and physiological psychology (Vol. 10, pp. 197-275). San Diego, CA: Academic Press.
11. Gormezano, I., Schneiderman, N., Deaux, E., & Fuentes, I. (1962). Nictitating membrane: Classical conditioning and extinction in the albino rabbit. Science, 138, 33-34.
12. Harkness, J. E., & Wagner, J. E. (1989). The biology and medicine of rabbits and rodents (3rd ed). Philadelphia: Lea and Febiger.
13. Hesslow, G. (1994). Correspondence between climbing fibre input and motor output in eyeblink-related areas in cat cerebellar cortex. Journal of Physiology, 15, 229-244.
14. Hesslow, G., Svensson, P., & Ivarsson, M. (1999). Learned movements elicited by direct stimulation of cerebellar mossy fiber afferents. Neuron, 24, 179-185.
15. Hilgard, E. R., & Marquis, D. G. (1935). Acquisition, extinction, and retention of the conditioned lid response to light in dogs. Journal of Comparative Psychology, 19, 29-58.
16. Hoehler, F. K., Kirschenbaum, D. S., & Leonard, D. W. (1973). The effects of overtraining and successive extinctions upon nictitating membrane conditioning in the rabbit. Learning and Motivation, 4, 91-101.
17. Hughes, B., & Schlosberg, H. (1938). Conditioning in the white rat: IV. The conditioned lid reflex. Journal of Experimental Psychology, 23, 641-650.
18. Kehoe, E. J. (1988). A layered network model of association learning: Learning-to-learn and configuration. Psychological Review, 95, 411-433.
19. Kim, J. J., Clark, R. E., & Thompson, R. F. (1995). Hippocampectomy impairs the memory of recently, but not remotely, acquired trace eyeblink conditioned responses. Behavioral Neuroscience, 109, 195-203.
20. Kleim, J. A., Freeman, J. H., Jr., Bruneau, R., Nolan, B. C., Cooper, N. R., Zook, A., & Walters, D. (2002). Synapse formation is associated with memory storage in the cerebellum. Proceedings of the National Academy of Sciences, USA, 99, 13228-13231.
21. Leonard, D. W., & Theios, J. (1967). Classical eyelid conditioning in rabbits under prolonged single alternation conditions of reinforcement. Journal of Comparative and Physiological Psychology, 64, 273-276.
22. Medina, J. F., Garcia, K. S., & Mauk, M. D. (2001). A mechanism for savings in the cerebellum. Journal of Neuroscience, 21, 4081-4089.
23. Millenson, J. R., Kehoe, E. J., & Gormezano, I. (1977). Classical conditioning of the rabbit's nictitating membrane response under fixed and mixed CS-US intervals. Learning and Motivation, 8, 351-366.
24. Moyer, J. R., Jr., Thompson, L. T., & Disterhoft, J. F. (1996). Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. Journal of Neuroscience, 16, 5536-5546.
25. Napier, R. M., Macrae, M., & Kehoe, E. J. (1992). Rapid reacquisition in conditioning of the rabbit's nictitating membrane response. Journal of Experimental Psychology: Animal Behavior Processes, 18, 182-192.
26. Nicholson, D. A., & Freeman, J. H., Jr. (2000). Developmental changes in eyeblink conditioning and neuronal activity in the inferior olive. Journal of Neuroscience, 20, 8218-8226.
27. Nicholson, D. A., & Freeman, J. H., Jr. (2002). Neuronal correlates of conditioned inhibition of the eyeblink response in the anterior interpositus nucleus. Behavioral Neuroscience, 116, 22-36.
28. Ohyama, T., & Mauk, M. D. (2001). Latent acquisition of timed responses in cerebellar cortex. Journal of Neuroscience, 21, 682-690.
29. Pavlov, I. P. (1927). Conditioned reflexes. London: Oxford University Press.
30. Paxinos, G. (Ed.). (1995). The rat nervous system (2nd ed). San Diego, CA: Academic Press.
31. Pellegrini, J. J., & Evinger, C. (1997). Role of cerebellum in adaptive modification of reflex blinks. Learning & Memory, 4, 77-87.
32. Power, J. M., Thompson, L. T., Moyer, J. R., Jr., & Disterhoft, J. F. (1996). Enhanced synaptic transmission in CA1 hippocampus after eyeblink conditioning. Journal of Neurophysiology, 78, 1184-1187.
33. Rogers, R. F., Britton, G. B., & Steinmetz, J. E. (2001). Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat. Brain Research, 905, 171-177.
34. Schmajuk, N. A., & Christiansen, B. A. (1990). Eyeblink conditioning in rats. Physiology & Behavior, 48, 755-758.
35. Schneiderman, N., Fuentes, I., & Gormezano, I. (1962). Acquisition and extinction of the classically conditioned eyelid response in the albino rabbit. Science, 136, 650-652.
36. Schreurs, B. G. (1993). Long-term memory and extinction of the classically conditioned rabbit nictitating membrane response. Learning and Motivation, 24, 293-302.
37. Schreurs, B. G., Gusev, P. A., Tomsic, D., Alkon, D. L., & Shi, T. (1998). Intracellular correlates of acquisition and long-term memory of classical conditioning in Purkinje cell dendrites in slices of rabbit cerebellar lobule HVI. Journal of Neuroscience, 18, 5498-5507.
38. Skelton, R. W. (1988). Bilateral cerebellar lesions disrupt conditioned eyelid responses in unrestrained rats. Behavioral Neuroscience, 102, 586-590.
39. Smith, M. C. (1968). CS-US interval and US intensity in classical conditioning of the rabbit's nictitating membrane response. Journal of Comparative and Physiological Psychology, 66, 679-687.
40. Smith, M. C., & Gormezano, I. (1965). Effects of alternating classical conditioning and extinction sessions on the conditioned nictitating membrane response of the rabbit. Psychonomic Science, 3, 91-92.
41. Spear, N. E. (1973). Retrieval of memory in animals. Psychological Review, 80, 163-194.
42. Stanton, M. E., Freeman, J. H., Jr., & Skelton, R. W. (1992). Eyeblink conditioning in the developing rat. Behavioral Neuroscience, 106, 657-665.
43. Thompson, L. T., Moyer, J. R., Jr., & Disterhoft, J. F. (1996). Transient changes in excitability of rabbit CA3 neurons with a time course appropriate to support memory consolidation. Journal of Neurophysiology, 76, 1836-1849.
44. Thompson, R. F., & Krupa, D. J. (1994). Organization of memory traces in the mammalian brain. Annual Review of Neuroscience, 17, 519-549.
45. Tracy, J. A., Thompson, J. K., Krupa, D. J., & Thompson, R. F. (1998). Evidence of plasticity in the pontocerebellar conditioned stimulus pathway during classical conditioning of the eyeblink response in the rabbit. Behavioral Neuroscience, 112, 267-285.
46. Weiss, C., Knuttinen, M. G., Power, J. M., Patel, R. I., O'Connor, M. S., & Disterhoft, J. F. (1999). Trace eyeblink conditioning in the freely moving rat: Optimizing the conditioning parameters. Behavioral Neuroscience, 113, 1100-1105.
47. Weiss, C., & Thompson, R. F. (1991). The effects of age on eyeblink conditioning in the freely moving Fischer-344 rat. Neurobiology of Aging, 12, 249-254.
48. Woodruff-Pak, D. S., & Steinmetz, J. E. (Eds.). (2000). Eyeblink classical conditioning: Animal. Amsterdam: Kluwer.