Thyroglobulin epitope recognition in a post iodine-supplemented Sri Lankan population

Clinical Endocrinology

Volumn 59, Issue 2, 2003, Pages 190-197

  Okosieme, O E ^a   Premawardhana, L D K E ^a   Jayasinghe, A ^b   De Silva, D G H ^c   Smyth, P P A ^d   Parkes, A B ^a   Lejeune, P J ^e   Ruf, J ^e   Lazarus, J H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF PERADENIYA   (Sri Lanka)

^c UNIVERSITY OF COLOMBO   (Sri Lanka)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

^e INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; AUTOANTIBODY; EPITOPE; IODINE; MONOCLONAL ANTIBODY; THYROGLOBULIN; THYROGLOBULIN ANTIBODY;

ADOLESCENT; ADULT; AGRICULTURAL WORKER; ANTIBODY TITER; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ETHNIC GROUP; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; SRI LANKA; THYROID DISEASE; UNITED KINGDOM;

ADOLESCENT; ADULT; AUTOANTIBODIES; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; DIETARY SUPPLEMENTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FEMALE; GREAT BRITAIN; HUMANS; IODINE; PREVALENCE; SRI LANKA; THYROGLOBULIN; THYROIDITIS, AUTOIMMUNE;

EID: 0042165847     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2003.01819.x     Document Type: Article

References (21)

1. Baker, J.R., Saunders, N.B., Tseng, Y.C., Wartofsky, L. & Burman, K.D.(1988) Seronegative Hashimoto's thyroiditis with thyroid antibody production localised to the thyroid. Annals of Internal Medicine, 108, 26-30.
2. Boukis, M.A., Koutras, D.A., Souvatzoglou, A., Evangelopolou, A., Vrotakis, M. & Moulopoulos, SD. (1983) Thyroid hormone and immunological studies in endemic goitre. Journal of Clinical Endocrinology and Metabolism, 57, 859-862.
3. Bresler, H.S., Burek, C.L., Hoffman, W.H. & Rose, N.R. (1990) Autoantigenic determinants on human thyroglobulin. II. Determinants recognized by autoantibodies from patients with chronic autoimmune thyroiditis compared to autoantibodies from healthy subjects. Clinical Immunology and Immunopathology, 54, 76-86.
4. Caturegli, P., Mariotti, S., Kuppers, C., Burek, C.L., Pinchera, A. & Rose, N.R. (1994) Epitopes on thyroglobulin: a study of patients with thyroid disease. Autoimmunity, 18, 41-49.
5. Delange, F. (1995) Correction of iodine deficiency: benefits and possible side-effects. European Journal of Endocrinology, 132, 542-543.
6. Estienne, V., McIntosh, R.S., Ruf, J., Asghar, M.S., Watson, P.F., Carayon, P. & Weetman, A.P. (1998) Comparative mapping of cloned human and murine antithyroglobulin antibodies: recognition by human antibodies of an unmunodominant region. Thyroid, 8, 643-646.
7. Foss, O., Hankes, L.V. & Van Slyke, D.D. (1960) A study of the alkaline ashing method for determination of protein-bound iodine in serum. Clinica Chimica Acta, 5, 301-326.
8. Groves, C.J., Howells, R.D., Williams, S., Darke, C. & Parkes, A.B. (1990) Primary standardization for the ELISA of serum thyroperoxidase and thyroglobulin antibodies and their prevalence in a normal Welsh population. Journal of Clinical and Laboratory Immunology, 32, 147-151.
9. Guilbert, B., Dighiero, G. & Avrameas, S. (1982) Naturally occurring antibodies against nine common antigens in human sera. Journal of Immunology, 128, 2779-2787.
10. Harach, H.R., Escalante, D.A., Onativia, A., Lederer Outes, J., Saravia Day, E. & Williams, E.D. (1985) Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis. Acta Endocrinologica, 108, 55-60.
11. Mallet, B., Lejeune, P.J., Ruf, J., Piechaczyk, M., Marriq, C. & Carayon, P. (1992) Tyrosine iodination and iodotyrosyl coupling of the N-terminal thyroid hormone forming site of human thyroglobulin modulate its binding to auto- and monoclonal antibodies. Molecular and Cellular Endocrinology, 88, 89-95.
12. Piechaczyk, M., Bouanani, M., Salhi, S.L., Baldet, L., Pau, B. & Bastide, J.M. (1987) Antigenic domains on the human thyroglobulin molecule recognised by autoantibodies in patients' sera and by natural autoantibodies isolated from sera of healthy subjects. Clinical Immunology and Immunopathology, 45, 114-121.
13. Premawardhana, L.D.K.E., Parkes, A.B., Smyth, P.P.A., Wijeyaratne, C.N., Jayasinghe, A., de Silva, D.G.H. & Lazarus, J.H. (2000) Increased prevalence of thyroglobulin antibodies in Sri Lankan schoolgirls: is iodine the cause? European Journal of Endocrinology, 143, 185-188.
14. Rose, N.R., Bresler, H.S., Burek, C.L., Gleason, S.L. & Kuppers, R.C. (1990) Mapping the autoepitopes of thyroglobulin. Israeli Journal of Medical Sciences, 26, 666-672.
15. Rose, N.R., Saboori, A.M., Rasooly, L. & Bureck, C.L. (1997) The role of iodine in autoimmune thyroiditis. Critical Reviews of Immunology, 17, 511-517.
16. Ruf, J., Carayon, P., Sarles-Phillips, N., Kourilsky, F. & Lissitzky, S. (1983) Specificity of monoclonal antibodies against human thyroglobulin: comparison with autoimmune antibodies. EMBO Journal, 2, 1821-1826.
17. Ruf, J., Carayon, P. & Lissitzky, S. (1985) Various expressions of a unique anti-human thyroglobulin antibody repertoire in a normal state and autoimmune disease. European Journal of Immunology, 15, 268-272.
18. Sundick, R.S., Bagchi, N. & Brown, T.R. (1992) The role of iodine in thyroid autoimmunity: from chickens to humans: a review. Autoimmunity, 13, 61-68.
19. Tomer, Y. (1997) Anti-thyroglobulin autoantibodies in autoimmune thyroid disease. Clinical Immunology and Immunopathology, 82, 3-11.
20. Weetman, A.P. & McGregor, A.M. (1984) Autoimmune thyroid disease: developments in our understanding. Endocrine Reviews, 5, 309-355.
21. Weetman, A.P. & Mcgregor, A.M. (1994) Autoimmune thyroid disease: further developments in our understanding. Endocrine Reviews, 15, 788-830.