Association between γ-glutamyl transpeptidase activity and status of disorders constituting insulin resistance syndrome

Alcoholism: Clinical and Experimental Research

Volumn 27, Issue 8 SUPPL., 2003, Pages

  Yokoyama, Hirokazu ^a,b   Moriya, Susumu ^b   Homma, Yasuhiko ^a   Ogawa, Tetsuhei ^a  

^a TOKAI UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

GTP; Ethanol consumption; Insulin resistance syndrome

Indexed keywords

ALCOHOL; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL; URIC ACID;

ADULT; ALCOHOL CONSUMPTION; CONFERENCE PAPER; DRINKING BEHAVIOR; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; HYPERURICEMIA; INSULIN RESISTANCE; LIVER FUNCTION; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; PRIORITY JOURNAL; QUESTIONNAIRE;

ADULT; AGED; BODY MASS INDEX; CHOLESTEROL; CHOLESTEROL, HDL; COMORBIDITY; CROSS-SECTIONAL STUDIES; GAMMA-GLUTAMYLTRANSFERASE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; JAPAN; LIVER DISEASES, ALCOHOLIC; METABOLIC SYNDROME X; MIDDLE AGED; RISK FACTORS; TRIGLYCERIDES; URIC ACID;

EID: 0042163151     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (25)

1. Allaway SL, Ritchie CD, Robinson D (1988) Detection of alcohol-induced fatty liver by computerized tomography. J R Soc Med 81:149-151.
2. Anton RF, Moak DH (1994) Carbohydrate-deficient transferrin and gamma-glutamyl transferase as markers of heavy alcohol consumption: gender difference. Alcohol Clin Exp Res 16:82-86.
3. Blazovicus A, Feher E, Feher J (1992) Role of free radical reactions in experimental hyperlipidemia in the pathogenesis of fatty liver, in Free Radicals and the Liver (Csomos G, Feher J eds), pp 96-123. Springer-Verlag, Berlin.
4. Braun JP, Vuillaume A, Benard P, Rico AG (1985) Enzyme patterns of the organs of the goose. Effects of fattening on liver enzymes. Ann Rech Vet 16:293-295.
5. Colloredo-Mels G, Bettale G, Bellati G (1988) Gamma glutamyl transpeptidase in diabetics: a case control study. Clin Chim Acta 175:189-195.
6. Hilden M, Clausen J (1975) Studies on the serum lipid and lipoproteins in steatosis of the liver. Acta Med Scand 198:207-212.
7. Lamy J, Baglin MC, Weill J, Aron E (1975) Serum gamma-glutamyl-transpeptidase and alcoholism. Diagnosis and control of withdrawal. Nouv Presse Med 4:487-490.
8. Martin JV, Hague RV, Martin PJ (1976) The association between serum triglycerides and gamma glutamyl transpeptidase activity in diabetes mellitus. Clin Biochem 9:208-211.
9. Moriya S, Nagata S, Yokoyama H, Kato S, Horie Y, Ito T, Ebihara Y, Ishii H (1994) Expression of gamma-glutamyl transpeptidase mRNA after depletion of glutathione in rat liver. Alcohol Alcohol 29(Suppl 1):107-111.
10. Nissen O, Forde OH, Brenn T (1990) The Tromso Study. Distribution and population determinants of gamma-glutamyl transferase. Am J Epidemiol 132:318-326.
11. Nomura F, Ohnishi K, Satomura Y (1986) Liver function in moderate obesity - study in 534 moderately obese subjects among 4613 male company employees. Int J Obes 10:349-354.
12. Nystrom M, Perasalo J, Pikkarainen J (1993) Conventional laboratory tests as indicators of heavy drinking in young university students. Scand J Prim Health Care 11:44-49.
13. Peterson B, Trell E, Kristensson H (1983) Comparison of gamma glutamyl-transferase and other health screening tests in average middle aged-males, heavy drinkers and alcohol non-users. Scand J Lab Invest 43:141-149.
14. Rantala AO, Lilija M, Kauma H (2000) Gamma glutamyl transpeptidase and the metabolic syndrome. J Intern Med 248:230-238.
15. Rao G (2001) Insulin resistance syndrome. Am Fam Physician 63:1159-1163, 1165-6.
16. Robinson D, Whitehead TP (1989) Effect of body mass and other factors on serum liver enzyme levels in men attending for well population screening. Ann Clin Biochem 26:393-400.
17. Speisky H, Shackel N, Varghese G (1990) Role of hepatic gamma-glutamyl transferase in the degradation of circulating glutathione: studies in the intact guinea pig perfused liver. Hepatology 11:843-849.
18. Szczeklik E, Orlowski M, Szewczuk A (1961) Serum γ-glutamyl transpeptidase activity in liver disease. Gastroenterology 41:353-359.
19. van Barneveld T, Seidell JC, Traag N (1989) Fat distribution and gamma glutamyl transferase in relation to serum lipids and blood pressure in 38-year-old Dutch males. Eur J Clin Nutr 43:809-818.
20. Wannamethee G, Ebrahim S, Shaper AG (1995) Gamma-glutamyl transferase; determinants and association with mortality from ischemic heart disease and all causes. Am J Epidemiol 142:699-708.
21. Whitfield JB, Allen JK, Adema M (1981a) Effects of age and sex on biochemical responses to drinking habits. Med J Aust 2:629-632.
22. Whitfield JB, Allen JK, Adema M (1981b) Effect of drinking on correlations between biochemical variables. Ann Clin Biochem 18:143-145.
23. Will Y, Fischer KA, Horton RA (2000) Gamma-glutamyl transpeptidase-deficient knockout mouse as a model to study the relationship between glutathione status, mitochondrial function, and cellular function. Hepatology 32:740-749.
24. Yamada Y, Ishizaki M, Kido T (1990) Relationship between serum gamma-glutamyl transpeptidase activity and blood pressure in middle-aged male and female non-drinkers. J Hum Hypertens 4:609-614.
25. Yokoyama H, Hirose H, Moriya S, Saito I (2002) Significant correlation between insulin resistance and serum gamma-glutamyl transpeptidase (γ-GTP) activity in non-drinkers. Alcohol Clin Exp Res 26:91S-94S.