Antagonists, inverse agonists, and protagonists

Journal of Clinical Psychopharmacology

Volumn 23, Issue 4, 2003, Pages 321-322

  Shader, Richard I ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; DOPAMINE 2 RECEPTOR; HISTAMINE H2 RECEPTOR; METHYLPHENIDATE; MU OPIATE RECEPTOR; NALTREXONE; OPIATE; OPIATE RECEPTOR; PIPERACETAZINE; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 7 RECEPTOR;

CALCULATION; DEPRESSION; DIAGNOSTIC ACCURACY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG MECHANISM; DRUG WITHDRAWAL; EDITORIAL; HUMAN; MORPHINE ADDICTION; OPIATE ADDICTION; POLITICS; PRIORITY JOURNAL; TREATMENT OUTCOME;

HUMANS; NARCOTIC ANTAGONISTS; NARCOTICS; RECEPTORS, OPIOID, MU;

EID: 0042133443     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.jcp.0000087502.38434.6c     Document Type: Editorial

References (6)

1. Martin WR, Jasinski DR, Mansky PA. Naltrexone, an antagonist for the treatment of heroin dependence. Arch Gen Psychiatry. 1973;28:784-791.
2. 2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice. J Pharmacol Exp Ther. 1996;277:484-490.
3. Wang D, Raehal KM, Bilsky EJ, et al. Inverse agonists and neutral antagonists at μ opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence. J Neurochem. 2001;77:1590-1600.
4. Wang Z, Bilsky EJ, Porreca F, et al. Constitutive μ-opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence. Life Sci. 1994;54:L339-PL350.
5. Milligan G, Bond RA. Inverse agonism and the regulation of receptor number. TiPS. 1997;468-474.
6. Milligan G, Ijzerman AP. Stochastic multidimensional hypercubes and inverse agonism. TiPS. 2000;362-363.