Experimental inoculation of the adult rat testis with Sendai virus: Effect on testicular morphology and leukocyte population

Human Reproduction

Volumn 18, Issue 8, 2003, Pages 1574-1579

  Melaine, N ^a   Ruffault, A ^b   Dejucq Rainsford, N ^a   Jégou, Bernard ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b RENNES UNIVERSITY HOSPITAL   (France)

Author keywords

Leukocytes; Orchitis; Sendai virus; Testis; Viral infection

Indexed keywords

MONOCLONAL ANTIBODY CD3; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EXPERIMENTATION; IMMUNOHISTOCHEMISTRY; INOCULATION; KIDNEY INTERSTITIUM; KIDNEY TUBULE; LEUKOCYTE COUNT; MACROPHAGE; MALE; MONOCYTE; MORPHOLOGY; MUMPS VIRUS; NONHUMAN; ORCHITIS; RAT; SCROTUM; SEMINIFEROUS TUBULE; SENDAI VIRUS; T LYMPHOCYTE; TESTIS; VIRUS INFECTION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; MUMPS VIRUS; RNA VIRUSES; SENDAI VIRUS;

EID: 0042123589     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deg323     Document Type: Article

References (30)

1. Aiman, J., Brenner, P.F. and MacDonald, P.C. (1980) Androgen and estrogen production in elderly men with gynecomastia and testicular atrophy after mumps orchitis. J. Clin. Endocrinol. Metab., 50, 380-386.
2. Bogen, C., Gilden, D.H., Wroblewska, Z. and Wolinsky, J.S. (1977) Experimental infection of human leukocytes with parainfluenza 1 (6/94) virus. Infect. Immun., 18, 501-508.
3. Chabon, A.B., Stenger, R.J. and Grabstald, H. (1987) Histopathology of testis in acquired immune deficiency syndrome. Urology, 29, 658-663.
4. Charny, C.W. and Meranze, D.R. (1948) Pathology of mumps orchitis. J. Urol., 60, 140.
5. Coronel, E.C., Takimoto, T., Murti, K.G., Varich, N. and Portner, A. (2001) Nucleocapsid incorporation into parainfluenza virus is regulated by specific interaction with matrix protein. J. Virol., 75, 1117-1123.
6. Csata, S. and Kulcsar, G. (1991) Virus-host studies in human seminal and mouse testicular cells. Acta Chir. Hung., 32, 83-90.
7. Dejucq, N. and Jégou, B. (2001) Viruses in the mammalian male genital tract and their effects on the reproductive system. Microbiol. Mol. Biol. Rev., 65, 208-231.
8. Dejucq, N., Dugast, I., Ruffault, A., van der Meide, P.H. and Jégou, B. (1995) Interferon-alpha and -gamma expression in the rat testis. Endocrinology, 136, 4925-4931.
9. Dejucq, N., Chousterman, S. and Jégou, B. (1997) The testicular antiviral defense system: Localization, expression and regulation of 2′5′ oligoadenylate synthetase, double-stranded protein kinase and Mx proteins in the rat seminiferous tubule. J. Cell Biol., 139, 865-873.
10. Dejucq, N., Leinard, M.O., and Guillaume, E., Dorval, I. and Jégou, B. (1998) Expression of interferons-alpha and -gamma in testicular interstitial tissue and spermatogonia of the rat. Endocrinology, 139, 3081-3087.
11. De Paepe, M.E. and Waxman, M. (1989) Testicular atrophy in AIDS: A study of 57 autopsy cases. Hum. Pathol., 20, 210-214.
12. Dijkstra, C.D., Dopp, E.A., Joling, P. and Kraal, G. (1985) The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3. Adv. Exp. Med. Biol., 186, 409-419.
13. El-Demiry, M.I., Hargreave, T.B., Busuttil, A., Elton, R., James, K. and Chisholm, G.D. (1987) Immunocompetent cells in human testis in health and disease. Fertil. Steril., 48, 470-479.
14. Gall, A.E. (1947) The histopathology of acute mumps orchitis. Am. J. Pathol., 23, 637.
15. Hedger, M.P. (1997) Testicular leukocytes: What are they doing? Rev. Reprod., 2, 38-47.
16. Kotronias, D. and Kapranos, N. (1998) Detection of herpes simplex virus DNA in human spermatozoa by in situ hybridization technique. In Vivo, 12, 391-394.
17. Lang, Z.W. (1993) Distribution of hepatitis B virus in testicle tissue in patients with hepatitis B infection. Zhonghua Yi Xue Za Zhi 73, 329-331.
18. Le Goffic, R., Mouchel, T., Aubry, F., Patard, J.J., Ruffault, A. Jégou, B. and Samson M. (2002) Production of the chemokines monocyte chemotactic protein-1, regulated on activation normal T cell expressed and secreted protein, growth-related oncogene and interferon-gamma-inducible protein-10 is induced by the Sendai virus in human and rat testicular cells. Endocrinology 143, 14344-1440.
19. Liu, F.H., Tian, G.S. and Fu, X.X. (1994) Detection of plus and minus strand hepatitis C virus RNA in peripheral blood mononuclear cells and spermatids. Chung-Hua I Hsuch Chih 74, 284-286.
20. Lyn, D., Mazanec, M.B., Nedrud, J.G. and Portner, A. (1991) Location of amino acid residues important for the structure and biological function of the haemagglutinin-neuraminidase glycoprotein of Sendai virus by analysis of escape mutants. J. Gen. Virol., 72, 817-824.
21. Melaine, N., Liénard, M.O., Guillaume, E., Ruffault, A., Dejucq-Rainsford, N., Jégou B. Production of antiviral protein 2′5′ oligo a dehylate synthetase PKR and Mx in interstitial cells and spermatogonia. J. Reprod. Immunol. 2003, in press.
22. Mikuz, G. and Damjanov, I. (1982) Inflammation of the testis, epididymis, peritesticular membranes and scrotum. Pathol. Annu., 17, 101-128.
23. Muciaccia, B., Filippini, A., Ziparo, E., Colelli, F., Baroni, C.D. and Stefanini M. (1998) Testicular germ cells of HIV-seropositive asymptomatic men are infected by the virus. J. Reprod. Immunol., 41, 81-93
24. Pirhonen, J., Sareneva, T., Kurimoto, M., Julkunen, I. and Matikainen, S. (1999) Virus infection activates IL-1 beta and IL-18 production in human macrophages by a caspase-1-dependent pathway. J. Immunol., 162, 7322-7329
25. Pöllänen, P. and Niemi, M. (1987) Immunohistochemical identification of macrophages, lymphoid cells and HLA antigens in the human testis. Int. J. Androl., 10, 37-42.
26. Rogers, C. and Klatt, E.C. (1988) Pathology of the testis in acquired immunodeficiency syndrome. Histopathology, 12, 659-665.
27. Stephan, J., Melaine, N., Ezan, E., Hakovirta, H., Maddocks, S., Toppari, J., Garnier, D., Wdzieczak-Bakala, J. and Jégou, B. (2000) Source, catabolism and role of the tetrapeptide N-acetyl-ser-asp-lys-Pro within the testis. J. Cell Sci., 113, 113-121.
28. Tebourbi, L., Courtot, A.M., Duchateau, R., Loeuillet, A., Testart, J. and Cerutti, I. (2001) Experimental inoculation of male mice with murine cytomegalovirus and effect on offspring. Hum. Reprod., 16, 2041-2049.
29. Wang, J., Wreford, N.G., Lan, H.Y., Atkins, R. and Hedger, M.P. (1994) Leukocyte populations of the adult rat testis following removal of the Leydig cells by treatment with ethane dimethane sulfonate and subcutaneous testosterone implants. Biol. Reprod., 51, 551-561.
30. Yoshikawa, Y., Truong, L.D., Fraire, A.E. and Kim, H.S. (1989) The spectrum of histopathology of the testis in acquired immunodeficiency syndrome. Mod. Pathol., 2, 233-238.