Influence of group A streptococcal acid glycoprotein on expression of major virulence factors and internalization by epithelial cells

Microbial Pathogenesis

Volumn 35, Issue 2, 2003, Pages 63-72

  Marouni, Mehran J ^a   Ziomek, Edmund ^b   Sela, Shlomo ^a,c  

^a TEL AVIV UNIVERSITY   (Israel)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c VOLCANI CENTER   (Israel)

Author keywords

Arginine deiminase; Internalization; SAGP; SpeB; Streptococcus pyogenes; Virulence genes

Indexed keywords

EXOTOXIN; GLYCOPROTEIN; M PROTEIN; PROTEINASE; PYROGENIC EXOTOXIN B; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CELL MUTANT; DOWN REGULATION; EPITHELIUM CELL; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INSERTION; GENE MUTATION; GENETIC TRANSCRIPTION; GROWTH RATE; INTERNALIZATION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATOR GENE; RNA TRANSLATION; STREPTOCOCCUS GROUP A; SYNTHESIS; TRANSPOSON;

INSERTION SEQUENCES; STREPTOCOCCUS PYOGENES; TRANSPOSONS;

EID: 0042121491     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0882-4010(03)00094-9     Document Type: Article

References (48)

1. Cunningham M.W. Pathogenesis of group A streptococcal infections. Clin Microbiol Rev. 13:2000;470-511.
2. Efstratiou A. Group A streptococci in the 1990s. J Antimicrob Chemother. 45:2000;S3-S12.
3. Schlievert P.M., Assimacopoulos A.P., Cleary P.P. Sever invasive group A streptococcal disease: clinical description and mechanisms of pathogenesis. J Lab Clin Med. 127:1996;13-22.
4. Stevens D.L. The toxins of group A streptococcus, the flesh-eating bacteria. Immunol Invest. 26:1997;129-150.
5. Stevens D.L. The flesh eating bacterium: what's next? J Infect Dis. 179:1999;S366-S374.
6. LaPenta D., Rubens C., Chi E., Cleary P.P. Group A streptococci efficiently invade human respiratory epithelial cells. Proc Natl Acad Sci USA. 91:1994;12115-12119.
7. Greco R., De Martino L., Donnarumma G., et al. Invasion of cultured human cells by Streptococcus pyogenes. Res Microbiol. 146:1995;551-560.
8. Osterlund A., Popa R., Nikkila T., Scheynius A., Engstrand L. Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis. Laryngoscope. 107:1997;640-647.
9. Jadoun J., Ozeri V., Burstein E., et al. Protein F1 is required for efficient entry of Streptococcus pyogenes into epithelial cells. J Infect Dis. 178:1998;147-158.
10. Molinari G., Chhatwal G.S. Invasion and survival of Streptococcus pyogenes in eukaryotic cells correlates with the source of the clinical isolates. J Infect Dis. 177:1998;1600-1607.
11. Schrager H.M., Rheinwald J.G., Wessels M.R. Hyaluronic acid capsule and the role of streptococcal entry into keratinocytes in invasive skin infection. J Clin Invest. 98:1996;1954-1958.
12. Wessels M.R., Goldberg J.B., Mosses A.E., DiCesare T.J. Effects on virulence of mutations in locus essential for hyaluronic acid capsule expression in group A streptococcus. Infect Immun. 62:1994;433-441.
13. Molinari G., Talay S.R., Valentin-Weigand P., Rohde M., Chhatwal G.S. The fibronectin-binding protein of Streptococcus pyogenes, SfbI, is involved in the internalization of group A streptococci by epithelial cells. Infect Immun. 65:1997;1357-1363.
14. Okada N., Tatsuno I., Hanski E., Caparon M., Sasakawa C. Streptococcus pyogenes protein F promotes invasion of HeLa cells. Microbiology. 144:1998;3079-3086.
15. Terao Y., Kawabata S., Kunitomo E., et al. Fba, a novel fibronectin-binding protein from Streptococcus pyogenes, promotes bacterial entry into epithelial cells, and the fba gene is positively transcribed under the Mga regulator. Mol Microbiol. 42:2001;75-86.
16. Berkower C., Ravins M., Moses A.E., Hanski E. Expression of different group A streptococcal M proteins in an isogenic background demonstrates diversity in adherence to and invasion of eukaryotic cells. Mol Microbiol. 31:1999;1463-1475.
17. Dombek P.E., Cue D., Sedgewick J., et al. High-frequency intracellular invasion of epithelial cells by serotype M1 group A streptococci: M1 protein mediated invasion and cytoskeletal rearrangements. Mol Microbiol. 31:1999;859-870.
18. Jadoun J., Sela S. Mutation in CsrR global regulator reduces Streptococcus pyogenes internalization. Microb Pathog. 29:2000;311-317.
19. Jadoun J., Eyal O., Sela S. Role of CsrR, hyaluronic acid, and SpeB in the internalization of Streptococcus pyogenes M type 3 by epithelial cells. Infect Immun. 70:2000;462-469.
20. Burns E.H. Jr., Lukomski S., Rurangirwa J., Podbielski A., Musser J.M. Genetic inactivation of the extracellular cysteine protease enhances in-vitro internalization of group A streptococci by human epithelial and endothelial cells. Microb Pathog. 24:1998;333-339.
21. Chaussee M.S., Cole R.L., Van-Putten J.P. Streptococcal erythrogenic toxin B abrogates fibronectin-dependent internalization of Streptococcus pyogenes by cultured mammalian cells. Infect Immun. 68:2000;3226-3232.
22. Tsai P.J., Kuo C.F., Lin K.Y., et al. Effect of group A streptococcal cysteine protease on invasion of epithelial cells. Infect Immun. 66:1998;1460-1466.
23. Ferretti J.J., McShan W.N., Ajdic D., et al. Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci USA. 98:2001;4658-4663.
24. Kanaoka M., Kawanaka C., Negoro T., et al. Cloning and expression of the antitumor glycoprotein gene of Streptococcus pyogenes Su in Escherichia coli. Agric Biol Chem. 51:1987;2641-2648.
25. Curran T.M., Lieou J., Marquis R.E. Arginine deiminase system and acid adaptation of oral streptococci. Appl Environ Microbiol. 61:1995;4494-4496.
26. Casiano-Colon A., Marquis R.E. Role of arginine deiminase system in protecting oral bacteria and an enzymatic basis for acid tolerance. Appl Environ Microbiol. 54:1988;1318-1324.
27. Degnan B.A., Fontaine M.C., Doebereiner A.H., et al. Characterization of isogenic mutant of Streptococcus pyogenes Manfredo lacking the ability to make streptococcal acid glycoprotein. Infect Immun. 68:2000;2441-2448.
28. Yoshida J., Yoshimura M., Takamura S., Kobayashi S. Purification and characterization of an antitumor principle from Streptococcus hemolyticus, SU strain. Jpn J Cancer Res. 76:1985;213-223.
29. Yoshida J., Takamura S., Nishio M. Characterization of streptococcal antitumor glycoprotein (SAGP). Life Sci. 62:1998;1043-1053.
30. Degnan B.A., Palmer J.M., Robson T., et al. Inhibition of human peripheral blood mononuclear cell proliferation by Streptococcus pyogenes cell extract is associated with arginine deiminase activity. Infect Immun. 66:1998;3050-3058.
31. Berge A., Bjorck L. Streptococcal cysteine proteinase releases biologically active fragments of streptococcal surface proteins. J Biol Chem. 270:1995;9862-9867.
32. Cue D., Dombek P.E., Lam H., Cleary P.P. Streptococcus pyogenes serotype M1 encodes multiple pathways for entry into human epithelial cells. Infect Immun. 66:1998;4593-4601.
33. Levin J.C., Wessels M.R. Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A streptococcus. Mol Microbiol. 30:1998;209-219.
34. Federle M.J., McIver K.S., Scott J.R. A response regulator that represses transcription of several virulence operons in the group A streptococcus. J Bacteriol. 181:1999;3649-3657.
35. Heath A., DiRita V.J., Barg N.L., Engleberg N.C. A two-component regulatory system CsrR-CsrS, represses expression of three Streptococcus pyogenes virulence factors, hyaluronic acid capsule, streptolysin S and pyrogenic exotoxin B. Infect Immun. 67:1999;5298-5305.
36. Graham M.R., Smoot L.M., Lux Migliaccio C.A., et al. Virulence control in group A streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci USA. 99:2002;13855-13860.
37. Natanson S., Sela S., Moses A.E., et al. Distribution of fibronectin-binding proteins among group A streptococci of different M types. J Infect Dis. 171:1995;871-878.
38. Perez-Casal J., Price J.A., Maguin E., Scott J.R. An M protein with a single C repeat prevents phagocytosis of Streptococcus pyogenes: use of a temperature-sensitive shuttle vector to deliver homologous sequences to the chromosome of S. pyogenes. Mol Microbiol. 8:1993;809-819.
39. Caparon M.G., Scott J.R. Genetic manipulation of pathogenic streptococci. Methods Enzymol. 204:1991;556-586.
40. Altschul S.F., Madden T.L., Schaffer A.A., et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 17:1997;3389-3402.
41. Sambrook J., Fritsch E., Maniatis T. Molecular cloning - a laboratory manual. 2nd ed:1989;Gold Spring Harbor Laboratory Press, New York.
42. Oginsky E.L. Isolation and determination of arginine and citrulline. Methods Enzymol. 3:1957;639-643.
43. Hauser A.R., Schlievert P.M. Nucleotide sequence of the streptococcal pyrogenic exotoxin type B gene and relationship between the toxin and the streptococcal proteinase precursor. J Bacteriol. 172:1990;4536-4542.
44. Nomizu M., Pietrzynski G., Kato T., et al. Substrate specificity of the streptococcal cysteine protease. J Biol Chem. 276:2001;44551-44556.
45. Barrett A.J., Kirschke H., Cathepsin B., Cathepsin H., Cathepsin L. Methods Enzymol. 80:1981;535-561.
46. Podbielski A., Melzaer B., Lutticken R. Application of the polymerase chain reaction to study the M protein (-like) gene family in beta-hemolytic streptococci. Med Microbiol Immunol. 180:1991;213-227.
47. Flannagan S.E., Zitzow L.A., Su Y.A., Clewell D.B. Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid. 32:1994;350-354.
48. DeAngelis P.L., Papaconstantinou J., Weigel P.H. Molecular cloning, identification, and sequence of the hyaluronan synthase gene from group A Streptococcus pyogenes. J Biol Chem. 268:1993;19181-19184.