General pharmacological properties of Shakuyaku-kanzo-to

Pharmacometrics

Volumn 64, Issue 1-2, 2003, Pages 23-31

  Takeda, Shuichi ^a   Goto, Kazuhiro ^a   Ishige, Atsushi ^a   Wei, Jiann Wu ^b   Ruo, Tsuen Ih ^b   Cheng, Fong Chi ^b   Aburada, Masaki ^a  

^a Tsumura Research Institute   (Japan)

^b MDS Pharma Services   (Taiwan)

Author keywords

General pharmacology; Shakuyaku kanzo to; Traditional Japanese medicine

Indexed keywords

ACETIC ACID; ACETYLCHOLINE; BARIUM CHLORIDE; HEXOBARBITAL; HISTAMINE; PAEONIA RADIX; PENTETRAZOLE; PENTOBARBITAL; SHAKUYAKU KANZO TO; UNCLASSIFIED DRUG; BU ZHONG YI QI TANG;

ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BODY TEMPERATURE; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CONVULSION; DOG; DRUG INHIBITION; ELECTRIC SHOCK; GASTROINTESTINAL TRACT; GUINEA PIG; ILEUM; ILEUM CONTRACTION; INTESTINE ABSORPTION; KIDNEY FUNCTION; LOCOMOTION; MALE; MOTOR COORDINATION; NONHUMAN; RAT; RESPIRATORY SYSTEM; SLEEP TIME; TAIL FLICK TEST; TRADITIONAL MEDICINE; WRITHING TEST; ANTICONVULSANT ACTIVITY; BREATHING RATE; CARDIOVASCULAR FUNCTION; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DRUG EFFECT; ELECTROCARDIOGRAM; ELECTROLYTE EXCRETION; FEMALE; FEMORAL ARTERY FLOW; GASTROINTESTINAL MOTILITY; HEART RATE; MOTOR DYSFUNCTION; NEUROLOGIC DISEASE; SYSTOLIC BLOOD PRESSURE; URINE PH; URINE VOLUME;

EID: 0042074463     PISSN: 03008533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Akao, T., Hayashi, T., Kobashi, K., Kanaoka, M., Kato, H., Kobayashi, M., Takeda, S. and Oyama, T. (1994): Intestinal bacterial hydrolysis is indispensable to absorption of 18β-glycyrrhetic acid after oral administration of glycyrrhizin in rats, J. Pharm. Pharmacol., 46, 135-137.
2. Armanini, D., Fiore, C., Mattarello, M.J., Bielenberg, J. and Palermo, M. (2002): History of the endocrine effects of licorice, Exp. Clin. Endocrinol. Diabetes, 110, 257-261.
3. Chen, G., Bohner, B. and Ensor, C.R. (1954): Evaluation of five methods for testing anticonvulsant activities, Proc. Soc. Exp. Biol. Med., 87, 334-339.
4. D'Amour, F.E. and Smith, D.L. (1941): A method for determining loss of pain sensation, J. Pharmacol Exp. Ther., 72, 74-79.
5. Dunham, N.W. and Miya, T.S. (1957): A note on a simple apparatus for detecting neurological deficit in rats and mice, J. Am. Pharmacut. Assoc. (Sci. Ed.), 46, 208-209.
6. Gylys, J.A., Muccia, P.M.R. and Taylor, M.K. (1963): Pharmacological and toxicological properties of 2-methyl-3-pyperidinopyrazine, a new antidepressant, Ann. N.Y. Acad. Sci., 107, 889-913.
7. Hirohashi, M., Takasuna, K., Yamashita, N. and Tamura, K. (1991): Pharmacological studies with the a2-adrenoceptor antagonist, Midaglizole, Arzneim. Forsch./Drug Res., 41, 9-18.
8. Inoue, K., Motonaga, A. and Nishimura, T. (1991): Mechanism of anti-inflammatory action of Etodolac, Arzneim. Forsch./Drug Res., 41, 235-239.
9. Irwin, S. (1968): Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse, Psychopharmacologia (Berl), 13, 222-257.
10. Lipschitz, W.L., Hadidian, Z. and Kerpcsar, A. (1943): Bioassay of diuretics, J. Pharmacol. Exp. Ther., 79, 97-110.
11. Maeda, T., Shinozuka, K., Baba, K., Hayashi, M. and Hayashi, E. (1983): Effect of Shakuyaku-kanzoh-toh, a prescription composed of Shakuyaku (Paeoniae radix) and Kanzoh (Glycyrrhizae radix) on guinea pig ileum, J. Pharm. Dyn., 6, 153-160.
12. Monder, C., Stewart, P.M., Lakshmi, V., Valentino, R., Burt, D. and Edwards, C.R.W. (1989): Licorice inhibits corticosteroid 11β-dehydrogenase of rat kidney and liver: in vivo and in vitro studies, Endocrinology, 125, 1046-1053.
13. Omosu, M., Komine, I., Becker, R.H.A. and Scholkens, B.A. (1988): General pharmacology of Ramipril, Arzneim. Forsch./Drug Res., 38, 1309-1317.
14. Takeda, S., Ishihara, K., Wakui, Y., Amagaya, S., Maruno, M., Akao, T. and Kobashi, K. (1996): Bioavailability study of glycyrrhetic acid after oral administration of glycyrrhizin in rats: relevance to the intestinal bacterial hydrolysis, J. Pharm. Pharmacol., 48, 902-905.
15. Turner, R. (1965): "Depressants of the central nervous system in screening methods in pharmacology", Volume I, pp. 69-86, Academic press, New York.
16. Yamauchi, H., Nishimura, K., Nakata, K., Suda, H., Iso, T., Shimizu, M. and Hiramatsu, Y. (1987): General pharmacological properties of the potent angiotensin converting enzyme inhibitor Rentiapril, Arzneim. Forsch./Drug Res., 37, 157-164.
17. Williams, P.D., Calligaro, D.O. and Corbert, W.E. (1991): General pharmacology of new potent 5-hydroxytryptamine antagonist, Arzneim. Forsch./Drug Res., 41, 189-198.