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Volumn 19, Issue 1, 1996, Pages 69-80

Immunomodulatory effects of interleukin-2 and interleukin-4 in patients with malignancy

Author keywords

Immunomodulatory; Interleukin 2; Interleukin 4; Phase I

Indexed keywords

CD16 ANTIGEN; CD2 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; DIPHENHYDRAMINE; HLA DR ANTIGEN; INDOMETACIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; PARACETAMOL; PETHIDINE; RECOMBINANT INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 4;

EID: 0042071830     PISSN: 10538550     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002371-199601000-00008     Document Type: Article
Times cited : (8)

References (39)
  • 1
    • 0023907493 scopus 로고
    • Interleukin-2: Inception, impact and implications
    • Smith KA. Interleukin-2: inception, impact and implications. Science 1988;240:1169-76.
    • (1988) Science , vol.240 , pp. 1169-1176
    • Smith, K.A.1
  • 2
    • 0022387502 scopus 로고
    • In vivo administration of purified human interleukin-2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2
    • Lotze MT, Matory YL, Ettinghausen SE, et al. In vivo administration of purified human interleukin-2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. J Immunol 1985;135: 2865-75.
    • (1985) J Immunol , vol.135 , pp. 2865-2875
    • Lotze, M.T.1    Matory, Y.L.2    Ettinghausen, S.E.3
  • 3
    • 0022414742 scopus 로고
    • Comparison of immunomodulatory and immunotherapeutic properties of biologic response modifiers
    • Talmadge JE, Chirigos MA. Comparison of immunomodulatory and immunotherapeutic properties of biologic response modifiers. Springer Semin Immunopathol 1985;8: 429-43.
    • (1985) Springer Semin Immunopathol , vol.8 , pp. 429-443
    • Talmadge, J.E.1    Chirigos, M.A.2
  • 4
    • 0025361437 scopus 로고
    • An improved method for growing murine tumor-infiltrating lymphocytes with in vivo antitumor activity
    • Yang JC, Perry-Lalley D, Rosenberg SA. An improved method for growing murine tumor-infiltrating lymphocytes with in vivo antitumor activity. J Biol Response Mod 1990; 9:149-59.
    • (1990) J Biol Response Mod , vol.9 , pp. 149-159
    • Yang, J.C.1    Perry-Lalley, D.2    Rosenberg, S.A.3
  • 5
    • 0021837706 scopus 로고
    • Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2
    • Rosenberg SA, Mule JJ, Speiss PJ, et al. Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2. J Exp Med 1985;161:1169-88.
    • (1985) J Exp Med , vol.161 , pp. 1169-1188
    • Rosenberg, S.A.1    Mule, J.J.2    Speiss, P.J.3
  • 6
    • 0022225701 scopus 로고
    • Adoptive immunotherapy of murine hepatic metastases with lymphokine activated killer (LAK) cells and recombinant interleukin 2 (rlL-2) can mediate the regression of both immunogenic and nonimmunogenic sarcomas and an adenocarcinoma
    • Lafreniere R, Rosenberg SA. Adoptive immunotherapy of murine hepatic metastases with lymphokine activated killer (LAK) cells and recombinant interleukin 2 (rlL-2) can mediate the regression of both immunogenic and nonimmunogenic sarcomas and an adenocarcinoma. J Immunol 1985; 135:4273-80.
    • (1985) J Immunol , vol.135 , pp. 4273-4280
    • Lafreniere, R.1    Rosenberg, S.A.2
  • 7
    • 0022473607 scopus 로고
    • A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes
    • Rosenberg SA, Spiess P, Lafreniere R. A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science 1986;233:1318-21.
    • (1986) Science , vol.233 , pp. 1318-1321
    • Rosenberg, S.A.1    Spiess, P.2    Lafreniere, R.3
  • 8
    • 0026813323 scopus 로고
    • Karnofsky Memorial Lecture. The immunotherapy and gene therapy of cancer
    • Rosenberg SA. Karnofsky Memorial Lecture. The immunotherapy and gene therapy of cancer. J Clin Oncol 1992;10: 180-99.
    • (1992) J Clin Oncol , vol.10 , pp. 180-199
    • Rosenberg, S.A.1
  • 9
    • 0023818703 scopus 로고
    • Molecular biology of interleukin 4 and interleukin 5 genes and biology of their products that stimulate B cells, T cells and hemopoietic cells
    • Yokota T, Arai N, de Vries J, et al. Molecular biology of interleukin 4 and interleukin 5 genes and biology of their products that stimulate B cells, T cells and hemopoietic cells. Immunol Rev 1988;102:137-87.
    • (1988) Immunol Rev , vol.102 , pp. 137-187
    • Yokota, T.1    Arai, N.2    De Vries, J.3
  • 10
    • 1442270503 scopus 로고
    • Interleukin-4 is a growth factor for activated thymocytes: Possible role in T-cell ontogeny
    • Zlotnik A, Ransom J. Frank G, et al. Interleukin-4 is a growth factor for activated thymocytes: possible role in T-cell ontogeny. Proc Natl Acad Sci USA 1987;84:3856-60.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3856-3860
    • Zlotnik, A.1    Ransom, J.2    Frank, G.3
  • 11
    • 0023250895 scopus 로고
    • Recombinant interleukin 4 promotes the growth of human T cells
    • Spits H, Yssel H, Takebe Y. et al. Recombinant interleukin 4 promotes the growth of human T cells. J Immunol 1987; 139:1142-7.
    • (1987) J Immunol , vol.139 , pp. 1142-1147
    • Spits, H.1    Yssel, H.2    Takebe, Y.3
  • 12
    • 0028285230 scopus 로고
    • Proliferating dendritic cell progenitors in human blood
    • Romani N, Gruner S. Brang D, et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994;180:83-93.
    • (1994) J Exp Med , vol.180 , pp. 83-93
    • Romani, N.1    Gruner, S.2    Brang, D.3
  • 13
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994;179:1109-18.
    • (1994) J Exp Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 14
    • 0024502120 scopus 로고
    • Murine interleukin-4 displays potent anti-tumor activity in vivo
    • Tepper RI, Pattengale PK, Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 1989;57:503-12.
    • (1989) Cell , vol.57 , pp. 503-512
    • Tepper, R.I.1    Pattengale, P.K.2    Leder, P.3
  • 15
    • 0026331269 scopus 로고
    • Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4
    • Golumbek PT, Lazenby AJ, Levitsky HI, et al. Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science 1991;254:713-16,
    • (1991) Science , vol.254 , pp. 713-716
    • Golumbek, P.T.1    Lazenby, A.J.2    Levitsky, H.I.3
  • 16
    • 0024210868 scopus 로고
    • Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma
    • Kawakami Y, Rosenberg SA, Lotze MT. Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma. J Exp Med 1988;168: 2183-91.
    • (1988) J Exp Med , vol.168 , pp. 2183-2191
    • Kawakami, Y.1    Rosenberg, S.A.2    Lotze, M.T.3
  • 17
    • 0023747688 scopus 로고
    • IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures
    • Spits H, Yssel H, Paliard X, et al. IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures. J Immunol 1988; 141:29-36.
    • (1988) J Immunol , vol.141 , pp. 29-36
    • Spits, H.1    Yssel, H.2    Paliard, X.3
  • 18
    • 0026703622 scopus 로고
    • Phase I trial of high-dose bolus interleukin-2 and interferon alpha-2a in patients with metastatic malignancy
    • Budd GT, Murthy S, Finke J, et al. Phase I trial of high-dose bolus interleukin-2 and interferon alpha-2a in patients with metastatic malignancy. J Clin Oncol 1992;10:804-9.
    • (1992) J Clin Oncol , vol.10 , pp. 804-809
    • Budd, G.T.1    Murthy, S.2    Finke, J.3
  • 19
    • 0021709032 scopus 로고
    • Immunohistology of lymphoproliferative disorders
    • Tubbs RR, Sheibani K. Immunohistology of lymphoproliferative disorders. Semin Diagn Pathol 1984;1:272-84.
    • (1984) Semin Diagn Pathol , vol.1 , pp. 272-284
    • Tubbs, R.R.1    Sheibani, K.2
  • 20
    • 0025311637 scopus 로고
    • Phase Ia-Ib trial of an anti-GD3 monoclonal antibody in combination with interferon-α in patients with malignant melanoma
    • Caulfield MJ, Barna B, Murthy S, et al. Phase Ia-Ib trial of an anti-GD3 monoclonal antibody in combination with interferon-α in patients with malignant melanoma. J Biol Response Mod 1990;9:319-28.
    • (1990) J Biol Response Mod , vol.9 , pp. 319-328
    • Caulfield, M.J.1    Barna, B.2    Murthy, S.3
  • 21
    • 0025264608 scopus 로고
    • + tumor-infiltrating lymphocytes in human renal cell carcinoma
    • + tumor-infiltrating lymphocytes in human renal cell carcinoma. Cancer Res 1990;50:2363-70.
    • (1990) Cancer Res , vol.50 , pp. 2363-2370
    • Finke, J.H.1    Rayman, P.2    Alexander, J.3
  • 22
    • 0028175152 scopus 로고
    • Phase I trial of subcutaneous recombinant macrophage colony-stimulating factor: Clinical and immunomodulatory effects
    • Bukowski RM, Budd GT, Gibbons JA, et al. Phase I trial of subcutaneous recombinant macrophage colony-stimulating factor: clinical and immunomodulatory effects. J Clin Oncol 1994;12:97-106.
    • (1994) J Clin Oncol , vol.12 , pp. 97-106
    • Bukowski, R.M.1    Budd, G.T.2    Gibbons, J.A.3
  • 23
    • 0001884644 scopus 로고
    • Individual comparisons by ranking methods
    • Wilcoxon F. Individual comparisons by ranking methods. Biometrics 1945;1:80-3.
    • (1945) Biometrics , vol.1 , pp. 80-83
    • Wilcoxon, F.1
  • 24
    • 84950646854 scopus 로고
    • A Friedman-type rank test for main effects in a two-factor ANOVA
    • Mack G, Skillings J. A Friedman-type rank test for main effects in a two-factor ANOVA. J Am Stat Assoc 1980;75: 947-51.
    • (1980) J Am Stat Assoc , vol.75 , pp. 947-951
    • Mack, G.1    Skillings, J.2
  • 25
    • 9244246438 scopus 로고
    • Role of IL-4 in the antitumor response
    • Spitz H, ed. Boca Raton, FL: CRC Press
    • Lotze M. Role of IL-4 in the antitumor response. In: Spitz H, ed. IL-4: structure and function. Boca Raton, FL: CRC Press, 1992:237.
    • (1992) IL-4: Structure and Function , pp. 237
    • Lotze, M.1
  • 26
    • 0026841369 scopus 로고
    • The treatment of patients with melanoma using interleukin-2, interleukin-4 and tumor infiltrating lymphocytes
    • Lotze MT. The treatment of patients with melanoma using interleukin-2, interleukin-4 and tumor infiltrating lymphocytes. Hum Gene Ther 1992;3:167-77.
    • (1992) Hum Gene Ther , vol.3 , pp. 167-177
    • Lotze, M.T.1
  • 27
    • 0028245157 scopus 로고
    • A phase I trial of continuous infusion interleukin-4 alone and following interleukin-2 in cancer patients
    • Sosman J, Fisher SG, Kefer C, et al. A phase I trial of continuous infusion interleukin-4 alone and following interleukin-2 in cancer patients. Ann Oncol 1994;5:447-552.
    • (1994) Ann Oncol , vol.5 , pp. 447-552
    • Sosman, J.1    Fisher, S.G.2    Kefer, C.3
  • 28
    • 9244234644 scopus 로고
    • A phase I trial of subcutaneous interleukin-2 and interleukin-4
    • Whitehead R, Friedman K, Clark D. A phase I trial of subcutaneous interleukin-2 and interleukin-4 [Abstract]. Proc Am Assoc Cancer Res 1992;33:1381.
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 1381
    • Whitehead, R.1    Friedman, K.2    Clark, D.3
  • 29
    • 0026551092 scopus 로고
    • Acute gastric mucosal injury associated with the systemic administration of interleukin-4
    • Rubin JT, Lotze MT. Acute gastric mucosal injury associated with the systemic administration of interleukin-4. Surgery 1992;111:274-280.
    • (1992) Surgery , vol.111 , pp. 274-280
    • Rubin, J.T.1    Lotze, M.T.2
  • 30
    • 0343170159 scopus 로고
    • Phase I study of recombinant human interleukin-4 (rHuIL-4) in patients with advanced cancer
    • Markowitz A, Kleinerman E, Hudson M, et al. Phase I study of recombinant human interleukin-4 (rHuIL-4) in patients with advanced cancer [Abstract]. Blood 1989;74(suppl): 146a.
    • (1989) Blood , vol.74 , Issue.SUPPL.
    • Markowitz, A.1    Kleinerman, E.2    Hudson, M.3
  • 31
    • 0026696410 scopus 로고
    • Recombinant human interleukin 4 (IL-4) given as daily subcutaneous injections - A phase I dose toxicity trial
    • Gilleece MH, Scarffee JH, Ghosh A, et al. Recombinant human interleukin 4 (IL-4) given as daily subcutaneous injections - a phase I dose toxicity trial. Br J Cancer 1992;66: 204-10.
    • (1992) Br J Cancer , vol.66 , pp. 204-210
    • Gilleece, M.H.1    Scarffee, J.H.2    Ghosh, A.3
  • 32
    • 0027385079 scopus 로고
    • Possible myocardial toxicity associated with interleukin-4 therapy
    • Trehu EG, Isner JM, Mier JW, et al. Possible myocardial toxicity associated with interleukin-4 therapy. J Immunother 1993;14:348-51.
    • (1993) J Immunother , vol.14 , pp. 348-351
    • Trehu, E.G.1    Isner, J.M.2    Mier, J.W.3
  • 33
    • 0027297088 scopus 로고
    • A phase I study of recombinant human interleukin-4 administered by the intravenous and subcutaneous route in patients with advanced cancer: Immunological studies
    • Ghosh AK, Smith NK, Prendiville J, et al. A phase I study of recombinant human interleukin-4 administered by the intravenous and subcutaneous route in patients with advanced cancer: immunological studies. Eur Cytokine Netw 1993;4: 205-11.
    • (1993) Eur Cytokine Netw , vol.4 , pp. 205-211
    • Ghosh, A.K.1    Smith, N.K.2    Prendiville, J.3
  • 34
    • 0023926926 scopus 로고
    • Infuence of dose and duration of infusion of interleukin-2 on toxicity and immunomodulation
    • Thompson JA, Lee DJ, Lindgren CG, et al. Infuence of dose and duration of infusion of interleukin-2 on toxicity and immunomodulation. J Clin Oncol 1988;6:669-78.
    • (1988) J Clin Oncol , vol.6 , pp. 669-678
    • Thompson, J.A.1    Lee, D.J.2    Lindgren, C.G.3
  • 35
    • 0023804208 scopus 로고
    • Repetitive weekly cycles of interleukin-2. II. Clinical and immunologic effects of dose, schedule, and addition of indomethacin
    • Sosman J, Kohler P, Hank J, et al. Repetitive weekly cycles of interleukin-2. II. Clinical and immunologic effects of dose, schedule, and addition of indomethacin. J Natl Cancer Inst 1988;80:1451-61.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 1451-1461
    • Sosman, J.1    Kohler, P.2    Hank, J.3
  • 36
    • 0024409831 scopus 로고
    • IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes
    • Kawakami Y, Custer MC, Rosenberg SA, et al. IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes. J Immunol 1989;142:3452-61.
    • (1989) J Immunol , vol.142 , pp. 3452-3461
    • Kawakami, Y.1    Custer, M.C.2    Rosenberg, S.A.3
  • 37
    • 0024378805 scopus 로고
    • Induction of lymphokine-activated killer activity by interleukin-4 in human lymphocytes preactivated by interleukin 2 in vivo or in vitro
    • Higuchi CM, Thompson JA, Lindgren CG, et al. Induction of lymphokine-activated killer activity by interleukin-4 in human lymphocytes preactivated by interleukin 2 in vivo or in vitro. Cancer Res 1989;49:6487-92.
    • (1989) Cancer Res , vol.49 , pp. 6487-6492
    • Higuchi, C.M.1    Thompson, J.A.2    Lindgren, C.G.3
  • 38
    • 0027259503 scopus 로고
    • Interleukin-4 and cancer therapy
    • Puri RK, Siegel JP. Interleukin-4 and cancer therapy. Cancer Invest 1993;11:473-86.
    • (1993) Cancer Invest , vol.11 , pp. 473-486
    • Puri, R.K.1    Siegel, J.P.2
  • 39
    • 0024827393 scopus 로고
    • Immunohistochemical correlates of response to recombinant interleukin-2 based immunotherapy in humans
    • Rubin JT, Elwood LJ, Rosenberg SA, et al. Immunohistochemical correlates of response to recombinant interleukin-2 based immunotherapy in humans. Cancer Res 1989;49:7086-92.
    • (1989) Cancer Res , vol.49 , pp. 7086-7092
    • Rubin, J.T.1    Elwood, L.J.2    Rosenberg, S.A.3


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