Effect of Dimethyl Sulfoxide and Dimethylformamide on the Stability of 4-Halo-8-quinolinols

Monatshefte fur Chemie

Volumn 134, Issue 8, 2003, Pages 1099-1104

  Gershon, Herman ^a,b   Clarke, Donald D ^a   McMahon, John J ^a  

^a FORDHAM UNIVERSITY   (United States)

^b NEW YORK BOTANICAL GARDEN   (United States)

Author keywords

3,5 Dibromo 4,8 quinolindiol; 4 Halo 8 quinolinols stable in pyridine d5; 5 Bromo 4,8 quinolindiol; 5 Chloro 4,8 quinolindiol; Degradation of 4 halo 8 quinolinols in DMSO and DMF

Indexed keywords

3,5 DIBROMO 4,8 DIHYDROXYQUINOLINE; 3,5 DIBROMO 4,8 QUINOLINDIOL; 3,5,7 TRIBROMO 4,8 DIHYDROXYQUINOLINE; 4,5 DIBROMO 8 QUINOLINOL; 4,5 DICHLORO 8 QUINOLINOL; 4,5,7 TRIBROMO 8 QUINOLINOL; 4,5,7 TRICHLORO 8 QUINOLINOL; 5 BROMO 4,8 DIHYDROXYQUINOLINE; 5 CHLORO 4,8 DIHYDROXYQUINOLINE; 5,7 DIBROMO 4,8 DIHYDROXYQUINOLINE; 5,7 DICHLORO 4,8 DIHYDROXYQUINOLINE; BROMINE; CHLORINE; DIMETHYL SULFOXIDE; N,N DIMETHYLFORMAMIDE; QUINOLINOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; DEGRADATION; DRUG STABILITY; HYDROLYSIS; REACTION ANALYSIS;

EID: 0042068177     PISSN: 00269247     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00706-003-0026-0     Document Type: Article

References (10)

1. Gershon H, Clarke DD, Gershon M (1999) Monatsh Chem 130: 653
2. Gershon H, Clarke DD, McMahon JJ, Gershon M (2001) Monatsh Chem 132: 833
3. Gershon H, Clarke DD, Gershon M (2001) Monatsh Chem 132: 1075
4. Fujita T, Price JM (1968) J Org Chem 33: 3004 and references therein
5. Joule JA, Smith GF (1972) Heterocyclic Chemistry, Van Nostrand Reinhold, New York, p 94
6. Gershon H, Clarke DD (1991) Monatsh Chem 122: 935
7. Lowry TH, Richardson KS (1981) Mechansim and Theory in Organic Chemistry, 2nd ed, Harper and Row, New York, p 163
8. Smith SG, Winstein S (1958) Tetrahedron 3: 317
9. Dalton DR, Dutta VP, Jones DC (1968) J Am Chem Soc 90: 5498
10. Dalton DR, Jones DG (1967) Tetrahedron Letters 30: 2875