MDR1-mediated interaction of digoxin with antiarrhythmic or antianginal drugs

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 12, 2002, Pages 1604-1607

  Kakumoto, Mikio ^a   Takara, Kohji ^b   Sakaeda, Toshiyuki ^a   Tanigawara, Yusuke ^c   Kita, Tomoko ^a   Okumura, Katsuhiko ^a  

^a KOBE UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

Author keywords

Antianginal drug; Antiarrythmic drug; Digoxin; Drug interaction; MDR1, P glycoprotein

Indexed keywords

AMIODARONE; ANTIANGINA PECTORIS AGENT; ANTIARRHYTHMIC AGENT; CIBENZOLINE; COMPLEMENTARY DNA; DIGOXIN; DISOPYRAMIDE; ISOSORBIDE; LIDOCAINE; MEXILETINE; MULTIDRUG RESISTANCE PROTEIN 1; QUINIDINE; TRITIUM; GLYCOPROTEIN P;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG ABSORPTION; GENE OVEREXPRESSION; IC 50; IN VITRO STUDY; KIDNEY EPITHELIUM; KIDNEY TUBULE EXCRETION; NONHUMAN; SWINE; ANGINA PECTORIS; ANIMAL; CELL STRAIN; DRUG EFFECT; DRUG INTERACTION; HUMAN; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

AMIODARONE; ANGINA PECTORIS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BIOLOGICAL TRANSPORT; DIGOXIN; DRUG INTERACTIONS; HUMANS; LLC-PK1 CELLS; P-GLYCOPROTEIN; QUINIDINE; SWINE;

EID: 0042037275     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.1604     Document Type: Article

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