Reassessment of the microbicidal activity of reactive oxygen species and hypochlorous acid with reference to the phagocytic vacuole of the neutrophil granulocyte

Journal of Medical Microbiology

Volumn 52, Issue 8, 2003, Pages 643-651

  Reeves, Emer P ^a   Nagl, Markus ^b   Godovac Zimmermann, Jasminca ^a   Segal, Anthony W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; MYELOPEROXIDASE; OXYGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ARTICLE; AUTORADIOGRAPHY; BACTERICIDAL ACTIVITY; BREATHING; CELL GRANULE; CELL VACUOLE; CHEMICAL REACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; GRANULE CELL; HUMAN; HUMAN CELL; IODINATION; MICROBIAL ACTIVITY; MICROORGANISM; NEUTROPHIL; OXIDATION; PH; PHAGOCYTE; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; TWO DIMENSIONAL GEL ELECTROPHORESIS;

CELLS, CULTURED; ESCHERICHIA COLI; HUMANS; HYDROGEN-ION CONCENTRATION; HYPOCHLOROUS ACID; IODINE RADIOISOTOPES; NEUTROPHILS; PEROXIDASE; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST; STAPHYLOCOCCUS AUREUS; VACUOLES;

EID: 0042028316     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.05181-0     Document Type: Article

References (38)

1. Aratani, Y., Koyama, H., Nyui, S. I., Suzuki, K., Kura, F. & Maeda, N. (1999). Severe impairment in early host defense against Candida albicans in mice deficient in myeloperoxidase. Infect Immun 67, 1828-1836.
2. Babior, B. M., Kipnes, R. S. & Curnutte, J. T. (1973). Biological defence mechanisms: the production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest 52, 741-744.
3. Babior, B. M., Curnutte, J. T. & Kipnes, R. S. (1974). Biological defense mechanisms. Evidence for the participation of superoxide in bacterial killing by xanthine oxidase. J Lab Clin Med 85, 235-244.
4. Belding, M. E. & Klebanoff, S. J. (1970). Peroxidase-mediated virucidal systems. Science 167, 195-196.
5. Brennan, M. L., Anderson, M. M., Shih, D. M. & 10 other authors (2001). Increased atherosclerosis in myeloperoxidase-deficient mice. J Clin Invest 107, 419-430.
6. Cech, P. & Lehrer, R. I. (1984). Phagolysosomal pH of human neutrophils. Blood 63, 88-95.
7. Chang, Y., Segal, B., Holland, S., Miller, G. & Kwon-Chung, K. (1998). Virulence of catalase-deficient Aspergillus nidulans in p47phox -/-mice. Implications for fungal pathogenicity and host defence in chronic granulomatous disease. J Clin Invest 101, 1843-1850.
8. Chapman, A. L., Hampton, M. B., Senthilmohan, R., Winterbourn, C. C. & Kettle, A. J. (2002). Chlorination of bacterial and neutrophil proteins during phagocytosis and killing of Staphylococcus aureus. J Biol Chem 277, 9757-9762.
9. Dychdala, G. R. (2001). Chlorine and chlorine compounds. In Disinfection, Sterilization and Preservation, 5th edn, pp. 135-158. Edited by S. S. Block. Philadelphia: Lippincott Williams & Wilkins.
10. Forehand, J. R., Nauseef, W. M., Curnutte, J. T. & Johnston, R. B. (1995). Inherited disorders of phagocyte killing. In The Metabolic and Molecular Bases of Inherited Disease, 7th edn, pp. 3995-4026. Edited by C. R. Scriver, A. L. Beaudet, W. S. Sly & D. Valle. New York: McGraw-Hill.
11. Henson, P. M. (1971). Interaction of cells with immune complexes: adherence, release of constituents and tissue injury. J Exp Med 134, 114-118.
12. Hurst, J. K. & Barrette, W. C., Jr (1989). Leukocytic oxygen activation and microbicidal oxidative toxins. Crit Rev Biochem Mol Biol 24, 271-328.
13. Jiang, Q., Griffin, D., Barofsky, D. & Hurst, J. (1997). Intraphagosomal chlorination dynamics and yields determined using unique fluorescent bacterial mimics. Chem Res Toxicol 10, 1080-1089.
14. Kettle, A. J. & Winterbourn, C. C. (1988). Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid. Biochem J 252, 529-536.
15. Kettle, A. J. & Winterbourn, C. C. (2001 ). A kinetic analysis of the catalase activity of myeloperoxidase. Biochemistry 40, 10204-10212.
16. Klebanoff, S. J. (1967a). Iodination of bacteria: a bactericidal mechanism. J Exp Med 126, 1063-1078.
17. Klebanoff, S. J. (1967b). A peroxidase-mediated antimicrobial system in leukocytes. J Clin Invest 126, 1063-1078.
18. Klebanoff, S. J. (1968). Myeloperoxidase-halide-hydrogen peroxide antibacterial system. J Bacteriol 95, 2131-2138.
19. Klebanoff, S. J. (1970). Myeloperoxidase: contribution to the microbicidal activity of intact leukocytes. Science 169, 1095-1097.
20. Klebanoff, S. J. (1975). Antimicrobial mechanisms in neutrophilic polymorphonuclear leukocytes. Semin Hematol 12, 117-142.
21. Klebanoff, S. J. & Clark, R. A. (1976). Iodination by human polymorphonuclear leukocytes: a re-evaluation. J Lab Clin Med 89, 675-686.
22. Lehrer, R. I. (1969). Antifungal effects of peroxidase systems. J Bacteriol 99, 361-365.
23. Mandell, G. L. & Hook, E. W. (1969). Leukocyte bactericidal activity in chronic granulomatous disease: correlation of bacterial hydrogen peroxide production and susceptibility to intracellular killing. J Bacteriol 100, 531-532.
24. Messina, C. G. M., Reeves, E. P., Roes, J. & Segal, A. W. (2002). Catalase negative Staphylococcus aureus retain virulence in mouse model of chronic granulomatous disease. FEBS Lett 518, 107-110.
25. Nagl, M., Hess, M., Pfaller, K., Hengster, P. & Gottardi, W. (2000). Bactericidal activity of micromolar N-chlorotaurine: evidence for its antimicrobial function in the human defence system. Antimicrob Agents Chemother 44, 2507-2513.
26. Olsen, R. & Little, C. (1982). Purification and some of the properties of myeloperoxidase and eosinophil peroxidase from human blood. Biochem J 209, 781-787.
27. + flux. Nature 416, 291-296.
28. 2 release from human granulocytes during phagocytosis. I. Documentation, quantitation and some regulating factors. J Clin Invest 55, 945-955.
29. Rosen, H. & Klebanoff, S. J. (1979). Bactericidal activity era superoxide anion-generating system. A model for the polymorphonuclear leukocyte. J Exp Med 149, 27-32.
30. Rosenfeld, J., Capdevielle, J., Guillemot, J. C. & Ferrara, P. (1992). In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis. Anal Biochem 203, 173-179.
31. Schiller, J., Benard, S., Reichl, S., Arnhold, J. & Arnold, K. (2000). Cartilage degradation by stimulated human neutrophils: reactive oxygen species decrease markedly the activity of proteolytic enzymes. Chem Biol 7, 557-568.
32. Segal, A. W. & Jones, O. T. (1980). Rapid incorporation of the human neutrophil plasma membrane cytochrome b into phagocytic vacuoles. Biochem Biophys Res Commun 92, 710-715.
33. Segal, A. W., Geisow, M., Garcia, R., Harper, A. & Miller, R. (1981 ). The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH. Nature 290, 406-409.
34. Segal, A. W., Garcia, R. C., Harper, A. M. & Banga, J. P. (1983). Iodination by stimulated human neutrophils. Studies on its stoichiometry, subcellular localization and relevance to microbial killing. Biochem J 210, 215-225.
35. Test, S. T., Lampert, M. B., Ossanna, P. J., Thoene, J. G. & Weiss, S. J. (1984). Generation of nitrogen-chlorine oxidants by human phagocytes. J Clin Invest 74, 1341-1349.
36. Thomas, E. L. (1979). Myeloperoxidase, hydrogen peroxide, chloride antimicrobial system: nitrogen-chlorine derivatives of bacterial components in bacterial action against Escherichia coli. Infect Immun 23, 522-531.
37. Thrasher, A. J., Keep, N. H., Wientjes, F. B. & Segal, A. W. (1994). Chronic granulomatous disease. Biochim Biophys Acta 1227, 1-24.
38. Vita, F., Borelli, V., Soranzo, M. R., Magnarin, M., Bertoncin, P. & Zabucchi, G. (1997). Preparation of membrane fractions from human neutrophil granules: a simple method. Methods Cell Sci 19, 197-205.