Differential contribution of natural killer cells to corneal graft rejection in 3-week-old versus mature rats

Transplantation

Volumn 76, Issue 3, 2003, Pages 578-582

  Mayer, Klaus ^a   Reinhard, Thomas ^a   Reis, Alexander ^a   Niehues, Tim ^a   Claas, Frans H ^b   Sundmacher, Rainer ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL INFILTRATION; CORNEA TRANSPLANTATION; FEMALE; GRAFT REJECTION; IMMATURITY; IMMUNOHISTOLOGY; INFLAMMATORY CELL; KERATOPLASTY; MACROPHAGE; NATURAL KILLER CELL; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

AGE FACTORS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOHISTOCHEMISTRY; KERATOPLASTY, PENETRATING; KILLER CELLS, NATURAL; MACROPHAGES; RATS; RATS, INBRED F344; RATS, INBRED LEW; RECEPTORS, INTERLEUKIN-2;

EID: 0041966203     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000074734.67751.E0     Document Type: Article

References (31)

1. Sundmacher R. Allograft rejection reactions after keratoplasty [author's transl]. Klin Monatsbl Augenheilkd 1977; 171: 705-722.
2. Cowden JW. Penetrating keratoplasty in infants and children. Ophthalmology 1990; 97: 324-328.
3. Reidy JJ. Penetrating keratoplasty in infancy and early childhood. Curr Opin Ophthalmol 2001; 12: 258-261.
4. Althaus C, Sundmacher R. Keratoplasty in newborns with Peters' anomaly. Ger J Ophthalmol 1996; 5: 31-35.
5. Schonherr U, Kuchle M, Lang GK, et al. Keratoplasty in childhood: Report of 71 keratoplasties. Klin Monatsbl Augenheilkd 1993; 203: 167-173.
6. Schaumberg DA, Moyes AL, Gomes JA, et al. Corneal transplantation in young children with congenital hereditary endothelial dystrophy: Multicenter Pediatric Keratoplasty Study. Am J Ophthalmol 1999; 127: 373-378.
7. Niederkorn JY. Mechanisms of corneal graft rejection: The sixth annual Thygeson Lecture, presented at the Ocular Microbiology and Immunology Group meeting, October 21, 2000. Cornea 2001; 20: 675-679.
8. Pleyer U, Dannowski H, Volk HD, et al. Corneal allograft rejection: Current understanding. I. Immunobiology and basic mechanisms. Ophthalmologica 2001; 215: 254-262.
9. Opremcak EM, Whisler RL, Dangel ME. Natural killer cells against human corneal endothelium. Am J Ophthalmol 1985; 99: 524-529.
10. Opremcak EM, Whisler RL, Dangel ME. In vitro demonstration of human natural killing of keratocytes and corneal epithelium. Ann Ophthalmol 1989; 21: 96-99, 102.
11. Ager A, Fajumi J, Sparshott SM, et al. Major histocompatibility complex control of NK-related allogeneic lymphocyte cytotoxicity in rats: The contributions of strong and medial transplantation antigens. Transplantation, 1988; 46: 762-767.
12. Rolstad B, Naper C, Lovik G, et al. Rat natural killer cell receptor systems and recognition of MHC class I molecules. Immunol Rev 2001; 181: 149-157.
13. Rolstad B. The athymic nude rat: An animal experimental model to reveal novel aspects of innate immune responses? Immunol Rev 2001; 184: 136-144.
14. Maier S, Tertilt C, Chambron N, et al. Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/- mice. Nat Med 2001; 7: 557-562.
15. Totterman TH, Hanas E, Bergstrom R, et al. Immunologic diagnosis of kidney rejection using FACS analysis of graft- infiltrating functional and activated T and NK cell subsets. Transplantation 1989; 47: 817-823.
16. Ruggeri L, Capanni M, Urbani E, et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002; 295: 2097-2100.
17. Lefkowitz M, Kornbluth J, Tomaszewski JE, et al. Natural killer-cell activity in cyclosporine-treated renal allograft recipients. J Clin Immunol 1988; 8: 121-127.
18. Herbort CP, Matsubara M, Nishi M, et al. Penetrating keratoplasty in the rat: A model for the study of immunosuppressive treatment of graft rejection. Jpn J Ophthalmol 1989; 33: 212-220.
19. Asma GE, Van den Bergh RL, Vossen JM. Use of monoclonal antibodies in a study of the development of T lymphocytes in the human fetus. Clin Exp Immunol 1983; 53: 429-436.
20. Marshall-Clarke S, Reen D, Tasker L, et al. Neonatal immunity: How well has it grown up? Immunol Today 2000; 21: 35-41.
21. Bowman LM, Holt PG. Selective enhancement of systemic Th1 immunity in immunologically immature rats with an orally administered bacterial extract. Infect Immun 2001; 69: 3719-3727.
22. Vetro SW, Bellanti JA. Fetal and neonatal immunomcompetence. Fetal Ther 1989; 4(suppl 1): 82-91.
23. Kovarik J, Siegrist CA. Immunity in early life. Immunol Today 1998; 19: 150-152.
24. Adkins B. T-cell function in newborn mice and humans. Immunol Today 1999; 20: 330-335.
25. Rothenberg EV. The development of functionally responsive T cells. Adv Immunol 1992; 51: 85-214.
26. Moretta A, Bottino C, Mingari MC, et al. What is a natural killer cell? Nat Immunol 2002; 3: 6-8.
27. Gill TJ III, Kunz HW, Misra DN, et al. The major histocompatibility complex of the rat. Transplantation 1987; 43: 773-785.
28. Sano Y, Ksander BR, Streilein JW, Minor H, rather than MHC, alloantigens offer the greater barrier to successful orthotopic corneal transplantation in mice. Transpl Immunol 1996; 4: 53-56.
29. Ortaldo JR, Mason A, Overton R. Lymphokine-activated killer cells: Analysis of progenitors and effectors. J Exp Med 1986; 164: 1193-1205.
30. Montagna D, Maccario R, Ugazio AG, et al. Natural cytotoxicity in the neonate: High levels of lymphokine activated killer (LAK) activity. Clin Exp Immunol 1988; 71: 177-181.
31. Reis A, Megahed M, Reinhard T, et al. Coadministration of the new macrolide immunosuppressant RAD and mycophenolate mofetil in experimental corneal transplantation. Transplantation 2000; 70: 1397-1401.