HBV DNA level and antigen concentration in evaluating liver damage of patients with chronic hepatitis B

Hepatobiliary and Pancreatic Diseases International

Volumn 2, Issue 3, 2003, Pages 418-422

  Xie, Yao ^a   Zhao, Hui ^a   Dai, Wang Su ^a   Xu, Dao Zhen ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

ALT; Antigen; HBeAg; HBV DNA; Hepatitis B; Hepatitis B virus

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; HEPATITIS B ANTIGEN; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL PRACTICE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CONVALESCENCE; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DISEASE MARKER; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CIRRHOSIS; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; POLYMERASE CHAIN REACTION; SEROLOGY; VIRUS LOAD;

ADOLESCENT; ADULT; AGED; DNA, VIRAL; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

EID: 0041911063     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Chun YK, Kim JY, Woo HJ, et al. No significant correlation exists between core promoter mutations, viral replication, and liver damage in chronic hepatitis B infection. Hepatology 2000;32:1154-1162.
2. Honda A, Yokosuka O, Fhata T, et al. Detection of mutations in the enhancer 2/core promoter region of hepatitis B virus in patients with chronic hepatitis B virus infection: comparison with in precore and core regions in relation to clinical status. J Med Virol 1999; 57:337-344.
3. Gerner P, Lausch E, Friedt M, et al. Hepatitis B virus core promoter mutations in children with multiple anti-HBe/HBeAg reactivation result in enhanced promoter activity. J Med Virol 1999;59:415-423.
4. Habersetzer F, Zoulim F, Jusot JF, et al. Clinical evaluation of the branched DNA assay for hepatitis B virus DNA detection in patients with chronic hepatitis B e antigen and treated with interferon-alpha. J Viral Hepat 1998;5:407-414.
5. Lindh M, Horal P, Dhillon AP, et al. Hepatitis B virus DNA levels, procure mutations, genotypes and histological activity in chronic hepatitis B. J Viral Hepat 2000;7:258-267.
6. Brunetto MR, Stemler M, Bonino F, et al. A new hepatitis B virus strain in patients with severe anti-HBe positive chronic hepatitis B. J Hepatol 1990;10:258-261.
7. Omata M, Ehata T, Yokosuka O, et al. Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. N Engl J Med 1991;324:1699-1704.
8. Grandjacques C, Pradat P, Stuyver L, et al. Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity. J Hepatol 2000;33:430-439.
9. Tu H, Xiong SD, Trepo C, et al. Frequency of hepatitis B virus e-minus mutants varies among patients from different areas of China. J Med Virol 1997;51:85-89.