T-cell-mediated mucosal immunity is attenuated in experimental necrotizing enterocolitis

Pediatric Surgery International

Volumn 19, Issue 5, 2003, Pages 326-330

  Anttila, A ^a   Kauppinen, H ^a   Koivusalo, A ^a   Heikkila, P ^a   Savilahti, E ^a   Rintala, R ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Immunohistochemistry; Intraluminal casein model; Lymphocyte subpopulations; Mucosal immunity; Necrotizing enterocolitis

Indexed keywords

CASEIN; CD1 ANTIGEN; CD2 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTIFICIAL MILK; CELL DENSITY; CELL FUNCTION; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE MODEL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; INTESTINE MUCOSA PERMEABILITY; MUCOSAL IMMUNITY; NECROTIZING ENTEROCOLITIS; NONHUMAN; PRIORITY JOURNAL; SWINE; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD; B-LYMPHOCYTES; CASEINS; CATTLE; ENTEROCOLITIS, NECROTIZING; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; MODELS, ANIMAL; SWINE; T-LYMPHOCYTES;

EID: 0041878476     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-003-1004-7     Document Type: Conference Paper

References (23)

1. Kosloske AM (1994) Epidemiology of necrotizing enterocolitis. Acta Paediatr (Suppl) 396:2-7
2. Beeby PJ, Jeffery H (1992) Risk factors for necrotising enterocolitis: the influence of gestational age. Arch Dis Child 67:432-435
3. Holman RC, Stoll BJ, Clarke MJ, Glass RI (1997) The epidemiology of necrotizing enterocolitis infant mortality in the United States. Am J Public Health 87:2026-2031
4. Stoll BJ (1994) Epidemiology of necrotizing enterocolitis. Clin Perinatol 21:205-218
5. Neu J (1996) Necrotizing enterocolitis: the search for a unifying pathogenic theory leading to prevention. Pediatr Clin North Am 43:409-432
6. Deitch EA (1994) Role of bacterial translocation in necrotizing enterocolitis. Acta Paediatr (Suppl) 396:33-36
7. Israel EJ (1994) Neonatal necrotizing enterocolitis, a disease of the immature intestinal mucosal barrier. Acta Paediatr (Suppl) 396:27-32
8. Mannick E, Udall JN Jr (1996) Neonatal gastrointestinal mucosal immunity. Clin Perinatol 23:287-304
9. Udall JN Jr (1990) Gastrointestinal host defense and necrotizing enterocolitis. J Pediatr 117:S33-S43
10. Clark DA, Thompson JE, Weiner LB, McMillan JA, Schneider AJ, Rokahr JE (1985) Necrotizing enterocolitis: intraluminal biochemistry in human neonates and a rabbit model. Pediatr Res 19:919-921
11. Lorenzo M di, Bass J, Krantis A (1995) An intraluminal model of necrotizing enterocolitis in the developing neonatal piglet. J Pediatr Surg 30:1138-1142
12. Koivusalo A, Kauppinen H, Anttila A, Heikkila P, Rintala R, Lindahl H (2000) Rectosigmoid pHi monitoring during experimental necrotizing enterocolitis. J Pediatr Surg 35:1462-1467
13. Denham S, Shimizu M, Bianchi ATJ, Zwart RJ, Carr MM, Parkhouse RME (1994) Monoclonal antibodies recognising differentiation antigens on porcine B cells. Vet Immunol Immunopathol 43:259-267
14. Pescovitz MD, Aasted B, Canals A, Dominguez J, Vizcaino JS, Pospisil R, Sinkora J, Salmon H, Valpotic I, Davis WC, Arn S, Sachs DH, Lunney JK, Zuckerman F, Weiland E, Saalmuller A (1994) Analysis of monoclonal antibodies reactive with the porcine CD2 antigen. Vet Immunol Immunopathol 43:229-232
15. Pescovitz MD, Aasted B, Canals A, Dominguez J, Vizcaino JS, Pospisil R, Trebichavsky I, Salmon H, Valpotic I, Davis WC, Arn S, Sachs DH, Lunney JK, Zuckerman F, Weiland E, Saalmuller A (1994) Analysis of monoclonal antibodies reactive with the porcine CD4 antigen. Vet Immunol Immunopathol 43:233-236
16. Saalmuller A, Aasted B, Canals A, Dominguez J, Goldman T, Lunney JK, Maurer S, Pescovitz MD, Pospisil R, Salmon H, Trebichavsky I, Valpotic I, Vizcaino JS, Zuckermann F (1994) Analyses of mAb reactive with porcine CD8. Vet Immunol Immunopathol 43:249-254
17. Zuckermann FA, Binns RM, Husmann R, Yang H, Carr MM, Kim YB, Davis WC, Misfeldt M, Lunney JK (1994) Analyses of monoclonal antibodies reactive with porcine CD44 and CD45. Vet Immunol Immunopathol 43:293-305
18. Crissinger KD (1995) Animal models of necrotizing enterocolitis. J Pediatr Gastroenterol Nutr 20:17-22
19. Nadler EP, Dickinson E, Knisely A, Zhang X-R, Boyle P, Beer-Stolz D, Watkins SC, Ford HR (2000) Expression of inducible nitric oxide synthase and interleukin-12 in experimental necrotizing enterocolitis. J Surg Res 92:71-77
20. Nathakumar NN, Fusunyan RD, Sanderson I, Walker WA (2000) Inflammation in the developing human intestine: a possible pathophysiologic contribution to necrotizing enterocolitis. PNAS 97:6043-6048
21. Halpern MD, Holubec H, Dominguez JA, Williams CS, Meza YG, McWilliam DL, Payne CM, McCuskey RS, Besselsen DG, Dvorak B (2002) Up-regulation of IL-18 and IL-12 in the ileum of neonatal rats with necrotizing enterocolitis. Pediatr Res 51:733-739
22. Shah NP (2000) Effects of milk-derived bioactives: an overview. Br J Nutr 84 (Suppl 1):S3-S10
23. Cross ML, Gill HS (2000) Immunomodulatory properties of milk. Br J Nutr 84 (Suppl 1):S81-S89