Diastereoselective synthesis of trans-N-benzyl-2-(2-methylphenyl)-6-phenyl-4-piperidone

Heterocycles

Volumn 55, Issue 8, 2001, Pages 1591-1597

  Ishimaru, Kaori ^a   Kojima, Takakazu ^a  

^a NATIONAL DEFENSE ACADEMY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0041874907     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-01-9271     Document Type: Article

References (25)

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22. unpublished data
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25. When the reaction of the aldimine derived from n-butanal with the 2-silyloxy-l,3-diene in the presence of silyl triflate was carried out at room temperature for 1 day, the use of TMSOTf, TBDMSOTf, or TIPSOTf gave 74% de (52% yield), 76% de (58% yield), or 80% de (75% yield), respectively.