In vitro metabolic studies of the novel anti-anxietic drug AF-5 and its metabolites in human liver microsome incubation system

Yaoxue Xuebao

Volumn 36, Issue 7, 2001, Pages 531-

  Li, Nong ^a   Zhang, Jin Lan ^a   Zhou, Tong Hui ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

AF 5; Anti anxietic drug; GC MS; Human liver microsomes

Indexed keywords

AF 5 COMPOUND; AF-5 COMPOUND; ANXIOLYTIC AGENT; FUSED HETEROCYCLIC RINGS;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; IN VITRO STUDY; LIVER MICROSOME; MASS FRAGMENTOGRAPHY; METABOLISM;

ANTI-ANXIETY AGENTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MICROSOMES, LIVER; MOLECULAR STRUCTURE;

EID: 0041836182     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. Zhang WJ. Study on drug metabolism [D]. Beijing: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 1997.
2. Von Bahr C, Groth CG, Jansson H, et al . Drug metabolism in human liver in vitro: Establishment of a human liver bank [J]. Clin Pharmacol Ther, 1980,27(6):711-725.