Cloning of a protein binding to the most proximal Pit-1 binding element of prolactin gene from human pituitary cDNA library

Molecular and Cellular Endocrinology

Volumn 207, Issue 1-2, 2003, Pages 31-38

  Fumoto, Mariko ^a   Okimura, Yasuhiko ^b   Sakagami, Yoshio ^c   Iguchi, Genzo ^a   Kishimoto, Masahiko ^a   Takahashi, Yutaka ^a   Kaji, Hidesuke ^d   Chihara, Kazuo ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c YODOGAWA CHRISTIAN HOSPITAL   (Japan)

^d Dept of Physiology and Biochemistry   (Japan)

Author keywords

cAMP; mPOU; Pit 1; PRL gene expression

Indexed keywords

BINDING PROTEIN; COMPLEMENTARY DNA; CYCLIC AMP; PROLACTIN; PROTEIN DERIVATIVE; PROTEIN MPOU; PROTEIN OCT 1; TRANSCRIPTION FACTOR PIT 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL STRAIN COS7; CONTROLLED STUDY; DNA LIBRARY; DNA SCREENING; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; HYBRID; HYPOPHYSIS; HYPOPHYSIS TUMOR; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROLACTIN SYNTHESIS; PROTEIN DNA BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REPORTER GENE; TISSUE DISTRIBUTION; YEAST;

EID: 0041834655     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(03)00207-7     Document Type: Article

References (23)

1. Anderson B., Schonemann M.D., Pearse R.V., Jenne K., Sugarman J., Rosenfeld M.G. Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex. J. Biol. Chem. 268:1993;23390-23398.
2. Arias J., Alberts A.S., Brindle P., Claret F.X., Smeal T., Karin M., Feramisco J. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature. 370:1994;226-229.
3. Bodner M., Castrillo J.L., Theill L.E., Deerinck T., Ellisman M., Karin M. The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein. Cell. 55:1988;505-518.
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
5. Bradford A.P., Conrad K.E., Wasylyk C., Wasylyk B., Gutierrez-Hartmann A. Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain. Mol. Cell. Biol. 15:1995;2849-2857.
6. Chrivia J.C., Kwok R.P., Lamb N., Hagiwara M., Montminy M.R., Goodmam R.H. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature. 365:1993;855-859.
7. Cui H., Bulleit R.F. Expression of the POU transcription factor Brn-5 inhibits proliferation of NG108-15 cells. Biochem. Biophys. Res. Commun. 236:1997;693-696.
8. Day R.N., Koike S., Sakai M., Muramatsu M., Maurer R.A. Both Pit-1 and the estrogen receptor are required for estrogen responsiveness of the rat prolactin gene. Mol. Endocrinol. 4:1990;1964-1971.
9. Diamond S.E., Chiono M., Gutierrez-Hartmann A. Recognition of the protein kinase A response of the rat prolactin promotor: differential effects of distinct Pit-1 isoforms and functional interaction with Oct-1. Mol. Endocrinol. 13:1999;228-238.
10. d'Emden M.C., Okimura Y., Maurer R.A. Analysis of functional cooperativity between individual transcription-stimulating elements in the proximal region of the rat prolactin gene. Mol. Endocrinol. 6:1992;581-588.
11. Fischberg, D.J., Chen, X.H., Bancroft, C., 1994. A pit-1 phosphorylation mutant can mediate both basal and induced prolactin and growth hormone promotor activity. Mol. Endocrinol. 8, 1566-1573.
12. Fliss M.S., Hinkle P.M., Bancroft C. Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity. Mol. Endocrinol. 13:1999;644-657.
13. Iguchi G., Okimura Y., Takahashi T., Mizuno I., Fumoto M., Takahashi Y., Kaji H., Abe H., Chihara K. Cloning and characterization of the 5′-flanking region of the human growth hormone-releasing hormone receptor gene. J. Biol. Chem. 274:1999;12108-12114.
14. Ingraham H.A., Chen R.P., Mangalam H.J., Elsholtz H.P., Flynn S.E., Lin C.R., Simmons D.M., Swanson L., Rosenfeld M.G. A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell. 55:1988;519-529.
15. Ingraham H.A., Flynn S.E., Voss J.W., Albert V.R., Kapiloff M.S., Wilson L., Rosenfeld M.G. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell. 61:1990;1021-1033.
16. Iverson R.A., Day K.H., d'Emden M., Day R.N., Maurer R.A. Clustered point mutation analysis of the rat prolactin promotor. Mol. Endocrinol. 4:1990;1564-1571.
17. Kapiloff M.S., Mathis J.M., Nelson C.A., Lin C.R., Rosenfeld M.G. Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements. Science. 253:1991;786-789.
18. Okamoto K., Wakamiya M., Noji S., Koyama E., Taniguchi S., Takemura R., Copeland N.G., Gilbert D.J., Jenkins N.A., Muramatsu M., Hamada H. A novel class of murine POU gene predominantly expressed in central nervous system. J. Biol. Chem. 268:1993;7449-7457.
19. Okimura Y., Howard P.W., Maurer R.A. Pit-1 binding sites mediate transcriptional responses to cyclic adenosine 3′, 5′-monophosphate through a mechanism that does not require inducible phosphorylation of Pit-1 can mediate both basal and induced prolactin and growth hormone promotor activity. Mol. Endocrinol. 8:1994;1566-1573.
20. Voss J.W., Wilson L., Rosenfeld M.G. POU-domain protein Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promotor. Genes Dev. 5:1991;1309-1320.
21. Wey E., Schafer B.W. Identification of novel DNA binding sites recognized by the transcription factor mPOU (POU6F1). Biochem. Biophys. Res. Commun. 220:1996;274-279.
22. Wey E., Lyons G.E., Schaefer B.W. A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues. Eur. J. Biochem. 220:1994;753-762.
23. Yan G., Bancroft C. Mediation by calcium of thyrotropin-releasing hormone action on the prolactin via transcription factor Pit-1. Mol. Endocrinol. 5:1991;1488-1497.