Study on the phase II metabolites of phenoprolamine hydrochloride in rat bile by LC/DAD/MSD

Yaoxue Xuebao

Volumn 36, Issue 6, 2001, Pages 440-443

  Ding, Li ^a   Zhang, Zheng Xing ^a   Ni, Pei Zhou ^a   Wang, Guang Ji ^a   An, Deng Kui ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Drug metabolism; LC DAD MSD; Phase II metabolite; Phenoprolamine hydrochloride

Indexed keywords

1 (2,6 DIMETHYLPHENOXY) 2 (3,4 DIMETHOXYPHENYLETHYLAMINO)PROPANE; 1 O (2,4 DIMETHYL 3 (2 METHYL 2 (3,4 DIMETHOXYPHENYLETHYLAMINO)ETHOXY)PHENYL)GLUCURONIC ACID; 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXYPHENYLETHYLAMINO)PROPANE; 1-O-(2,4-DIMETHYL-3-(2-METHYL-2-(3,4-DIMETHOXYPHENYLETHYLAMINO)ETHOXY)PHENYL)GLUCURONIC ACID; ANTIHYPERTENSIVE AGENT; GLUCURONIDE; PHENETHYLAMINE DERIVATIVE;

ANIMAL; ARTICLE; BILE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MALE; METABOLISM; RAT; RAT STRAIN;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BILE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENGLISH ABSTRACT; GLUCURONIDES; MALE; PHENETHYLAMINES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUPPORT, NON-U.S. GOV'T;

EID: 0041830953     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. 1-adrenoceptor antagonist DDPH analogs [J]. J China Pharm Univ (in Chinese), 1996,27(7):395-400.
2. 1-adrenoceptor antagonist DDPH [J]. J China Pharm Univ (in Chinese), 1998,29(2):81-91.
3. Ding L, Zhang ZX, Ni PZ, et al. Study on the phase I metabolites of phenoprolamine hydrochloride in rat bile by LC/DAD/MSD [J]. Acta Pharm Sin (in Chinese), 2001,36(3):205-209.
4. Ding L, Zhang ZX, Cheng H, et al. Simultaneous determination of four metabolites of phenoprolamine hydrochloride and their pharmacokinetics in rat bile by HPLC [J]. J China Pharm Univ (in Chinese), 2000, 31(2):115-117.