Excitation of fluorescent dyes inactivates the outer hair cell integral membrane motor protein prestin and betrays its lateral mobility

Pflugers Archiv European Journal of Physiology

Volumn 446, Issue 5, 2003, Pages 617-622

  Santos Sacchi, Joseph ^a   Zhao, Hong Bo ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Di 8 ANEPPS; Fluorescein; FRAP; Gating charge; Lucifer yellow; Membrane capacitance; Outer hair cell

Indexed keywords

4 [2 [6 (DIOCTYLAMINO) 2 NAPHTHALENYL]ETHENYL] 1 (3 SULFOPROPYL)PYRIDINIUM; 6 CARBOXYFLUORESCEIN; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; LUCIFER YELLOW; MEMBRANE PROTEIN; PRESTIN; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL MOTILITY; CELL MOTION; CHANNEL GATING; CONTROLLED STUDY; DIFFUSION; FIBER OPTICS; FLUORESCENCE; GUINEA PIG; HAIR CELL; HEARING; ILLUMINATION; LIGHT EXPOSURE; MAMMAL; MEMBRANE BINDING; MEMBRANE CURRENT; MEMBRANE STRUCTURE; NONHUMAN; NONLINEAR SYSTEM; OUTER HAIR CELL LATERAL MEMBRANE; PHOTOACTIVATION; POPULATION EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIME;

ANIMALS; CELL MEMBRANE; FLUORESCEINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENT DYES; GUINEA PIGS; HAIR CELLS, OUTER; ISOQUINOLINES; MODELS, CHEMICAL; MOLECULAR MOTOR PROTEINS; PROTEINS; PYRIDINIUM COMPOUNDS;

EID: 0041828382     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-003-1053-8     Document Type: Article

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