Different roles of ERK 1/2 and p38 MAPK α/β in cellular signaling during cardiomyocyte anoxia preconditioning

Acta Physiologica Sinica

Volumn 55, Issue 4, 2003, Pages 454-458

  Huang, Yi Feng ^a   Gong, Kai Zheng ^a   Zhang, Zhen Gang ^a  

^a YANGZHOU UNIVERSITY   (China)

Author keywords

Anoxia; Cytoprotection; Extracellular signal regulated kinase; Ischemic preconditioning, myocardial; p38 mitogen activated protein kinases; Physiology

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3,4 METHYLENEDIOXYAMPHETAMINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MYELIN BASIC PROTEIN; SUPEROXIDE DISMUTASE; SYNAPTOPHYSIN;

ANIMAL CELL; ANOXIA; ARTICLE; CELL DAMAGE; CELL HYPOXIA; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HEART INFARCTION PREVENTION; HEART MUSCLE CELL; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; REOXYGENATION; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; CELL HYPOXIA; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 0041823328     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Zhang JH (Chinese), Zhang ZG, Zhang M, Wang LH. Roles of PKC in the mechanism of ischemic preconditioning protection in isolated rat heart. Chin J Cardiol (Chinese character) 1995;23:456-459 (Chinese, English abstract).
2. Dong F (Chinese character), Gong KZ, Zhang ZG, Lv S. Roles of PKC and ERK in the mechanism of delayed protection of anoxia preconditioning in rat cardiac myocyte. Chin J Pathophysiol 2003 (Chinese character);19:503-506 (Chinese, English abstract).
3. Sato M, Cordis GA, Maulik N, Das DK. Inhibition of either p38 MAPK or JNK1 abolished the cardioprotective effects of preconditioning. SAPKs regulation of ischemic preconditioning. Am J Physiol Heart Circ Physiol 2000;279:H901-H907.
4. Ma XL, Kumar S, Gao F, Louden CS, Lopez BL, Christopher TA, Wang C, Lee JC, Feuerstein GZ, Yue TL. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 1999;99:1685-1691.
5. Li TC (Chinese character), Pang YZ, Su JY, Tang CS. Measurement of mitogen-activated protein kinases activity. Basic Med Sci Clin (Chinese charaacter) 1996;16(2):78-80 (Chinese).
6. Lazou A, Bogoyevitch MA, Clerk A, Fuller SJ, Marshall CJ, Sugden PH. Regulation of mitogen-activated protein kinase cascade in adult rat heart preparation in vitro. Circ Res 1994;75:932-941.
7. Bogoyevitch MA, Glennon PE, Andersson MB, Clerk A, Lazou A, Marshall CJ, Parker P, Sugden PH. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes: the potential role the cascade in the integration of two signaling pathways leading to myocytes hypertrophy. J Biol Chem 1994;269:1110-1119.
8. Maulik N, Yoshida T, Zu YL, Sato M, Banerjee A, Das DK. Ischemic preconditioning triggers tyrosine kinase signaling: a potential role for MAPKAP kinase 2. Am J Physiol 1998;275:H1857-H1864.
9. ATP channels. Am J Physiol Heart Circ Physiol 2001;280:H1278-H1285.
10. Nakano A, Baines CP, Kim SO, Pelech SL, Downey JM, Cohen MV, Critz SD. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK. Circ Res 2000;86:144-151.
11. Punn A, Mockridge JW, Farooqui S, Marber MS, Heads RJ. Sustained activation of p42/p44 mitogen-activated protein kinase during recovery from simulated ischaemia mediates adaptive cytoprotection in cardiomyocytes. Biochem J 2000;350:891-899.
12. Brondello JM, Brunet A, Pouyssegur J, McKenzie FR. The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/ p44 MAPK cascade. J Biol Chem 1997;272:1368-1376.