High frequency stimulation of the subthalamic nucleus has beneficial antiparkinsonian effects on motor functions in rats, but less efficiency in a choice reaction time task

European Journal of Neuroscience

Volumn 18, Issue 4, 2003, Pages 951-956

  Darbaky, Yassine ^a   Forni, Claude ^a   Amalric, Marianne ^a   Baunez, Christelle ^a  

^a CNRS   (France)

Author keywords

Basal ganglia; Circling behaviour; Cognitive functions; Deep brain stimulation; Dopamine; Substantia nigra

Indexed keywords

APOMORPHINE; DOPAMINE; HALOPERIDOL; MAZINDOL; NEUROLEPTIC AGENT; OXIDOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN DEPTH STIMULATION; CATALEPSY; CATECHOLAMINE DEPLETION; CIRCLING BEHAVIOR; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; HIGH FREQUENCY STIMULATION; INSTRUMENTAL CONDITIONING; MALE; MOTOR PERFORMANCE; NONHUMAN; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; RAT; RESPONSE TIME; SENSORIMOTOR FUNCTION; STATISTICAL SIGNIFICANCE; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS; TASK PERFORMANCE; TREATMENT OUTCOME; WAKEFULNESS;

ADRENERGIC AGENTS; ANIMALS; ANTI-DYSKINESIA AGENTS; ANTIPARKINSON AGENTS; APOMORPHINE; CATALEPSY; CHOICE BEHAVIOR; COGNITION; CONDITIONING, OPERANT; ELECTRIC STIMULATION THERAPY; FUNCTIONAL LATERALITY; HALOPERIDOL; MALE; MODELS, ANIMAL; MOTOR ACTIVITY; OXIDOPAMINE; PARKINSON DISEASE; RATS; RATS, LONG-EVANS; REACTION TIME; SUBTHALAMIC NUCLEUS;

EID: 0041817605     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02803.x     Document Type: Article

References (37)

1. Alegret, M., Junque, C., Valldeoriola, F., Vendrell, P., Pilleri, M., Rumia, J. & Tolosa, E. (2001) Effects of bilateral subthalamic stimulation on cognitive function in Parkinson disease. Arch. Neurol., 58, 1205-1206.
2. Aziz, T.Z., Peggs, D., Sambrook, M.A. & Crossman, A.R. (1991) Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced parkinsonism in the primate. Mov. Disord., 6, 288-292.
3. Baunez, C., Amalric, M. & Robbins, T.W. (2002) Enhanced food-related motivation after bilateral lesions of the subthalamic nucleus. J. Neurosci., 22, 562-568.
4. Baunez, C., Nieoullon, A. & Amalric, M. (1995) In a rat model of parkinsonism, lesions of the subthalamic nucleus reverse increases of reaction time, but induce a dramatic premature responding deficit. J. Neurosci., 15, 6531-6541.
5. Baunez, C. & Robbins, T.W. (1997) Bilateral lesions of the subthalamic nucleus induce multiple deficits in an attentional task in rats. Eur. J. Neurosci., 9, 2086-2099.
6. Baunez, C. & Robbins, T.W. (1999) Effects of dopamine depletion of the dorsal striatum and further interaction with subthalamic nucleus lesions in an attentional task in the rat. Neuroscience, 92, 1343-1356.
7. Benabid, A.L., Koudsie, A., Benazzouz, A., Piallat, B., Krack, P., Limousin-Dowsey, P., Lebas, J.F. & Pollak, P. (2001) Deep brain stimulation for Parkinson's disease. Adv. Neurol., 86, 405-412.
8. Benazzouz, A., Gao, D.M., Ni, Z.G., Piallat, B., Bouali-Benazzouz, R. & Benabid, A.L. (2000) Effect of high frequency stimulation of the subthalamic nucleus on the neuronal activities of the substantia nigra pars reticulata and ventrolateral nucleus of the thalamus in the rat. Neuroscience, 99, 289-295.
9. Benazzouz, A., Gross, C., Féger, J., Boraud, T. & Bioulac, B. (1993) Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkey. Eur. J. Neurosci., 5, 382-389.
10. Benazzouz, A., Piallat, B., Pollak, P. & Benabid, A.L. (1995) Responses of substantia nigra pars reticulata and globus pallidus complex to HFS of the subthalamic nucleus in rats: electrophysiological data. Neurosci. Lett., 189, 77-80.
11. Bergman, H., Wichmann, T. & DeLong, M.R. (1990) Reversal of experimental parkinsonism by lesion of the subthalamic nucleus. Science, 249, 1436-1438.
12. Beurrier, C., Bioulac, B., Audin, J. & Hammond, C. (2001) High-frequency stimulation produces a transient blockade of voltage-gated currents in subthalamic neurons. J. Neurophysiol., 85, 1351-1356.
13. Burbaud, P., Gross, C., Benazzouz, A., Coussemacq, M. & Bioulac, B. (1995) Reduction of apomorphine-induced rotational behavior by subthalamic lesion in 6-OHDA lesioned rats is associated with a normalization of firing rate and discharge pattern of pars reticulata neurons. Exp. Brain Res., 105, 48-58.
14. Carli, M., Evenden, J. & Robbins, T.W. (1985) Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention. Nature, 313, 679-682.
15. Dujardin, K., Defebvre, L., Krystkowiak, P., Blond, S. & Destee, A. (2001) Influence of chronic bilateral stimulation of the subthalamic nucleus on cognitive function in Parkinson's disease. J. Neurol. 248, 603-611.
16. Gao, D.M., Benazzouz, A., Piallat, B., Bressand, K., Ilinsky, I.A., Kultas-Ilinsky, K. & Benabid, A.L. (1999) High-frequency stimulatioh of the subthalamic nucleus suppresses experimental resting tremor in the monkey. Neuroscience, 88, 201-212.
17. Gill, S.S. & Heywood, P. (1997) Bilateral dorsolateral subthalamotomy for advanced Parkinson's disease. Lancet, 350, 1224.
18. Hajji, M.D., Salin, P. & Kerkerian-LeGoff, L. (1996) Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephaline but not on substance P expression in rat striatum. Eur. J. Neurosci., 8, 917-926.
19. Henderson, J.M., Annett, L.E., Ryan, L.J., Chiang, W., Hidaka, S., Torres, E.M. & Dunnett, S.B. (1999) Subthalamic nucleus lesions induce deficits as well as benefits in the hemiparkinsonian rat. Eur. J. Neurosci., 11, 2749-2757.
20. Javitch, J.A., Strittmatter, S.M. & Snyder, S.H. (1985) Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography. J. Neurosci., 5, 1513-1521.
21. Limousin, P., Pollak, P., Benazzouz, A., Hoffmann, D., Lebas, J.F., Broussole, E., Perret, J.E. & Benabid, A.L. (1995) Effects on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation. Lancet, 345, 91-95.
22. Morelli, M. & Di Chiara, G. (1990) Stereospecific blockade of N-methyl-D-Aspartate transmission by MK801 prevents priming of SKF 38393-induced turning. Psychopharmacology, 101, 287-288.
23. Murer, M.G., Sinay, V. & Pazo, J.H. (1995) Turning behavior in rats with unilateral lesions of the subthalamic nucleus: synergism between D1 and D2 receptors. J. Neural Transm. General Sect., 100, 123-135.
24. Paxinos, G. & Watson, C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, New York.
25. Perier, C., Vila, M., Féger, J., Agid, Y. & Hirsch, E.C. (2000) Functional activity of zona incerta neurons is altered after nigrostriatal denervation in hemiparkinsonian rats. Exp. Neurol., 162, 215-224.
26. Phillips, J.M. & Brown, V.J. (1999) Reaction time performance following unilateral striatal dopamine depletion and lesions of the subthalamic nucleus in the rat. Eur. J. Neurosci., 11, 1003-1010.
27. Robledo, P. & Féger, J. (1991) Acute monoaminergic depletion in the rat potentiates the excitatory effect of the subthalamic nucleus in the substantia nigra pars reticulata but not in the pallidal complex. J. Neural Transm. General Sect., 86, 115-126.
28. Saint-Cyr, J.A., Trepanier, L.L., Kumar, R., Lozano, A.M. & Lang, A.E. (2000) Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease. Brain, 123, 2091-2108.
29. Salin, P., Manrique, C., Forni, C. & Kerkerian-Le Goff, L. (2002) High-frequency stimulation of the subthalamic nucleus selectively reverses dopamine denervation-induced cellular defects in the output structures of the basal ganglia in the rat. J. Neurosci., 22, 5137-5148.
30. Schallert, T., Upchurch, M., Lobaugh, N., Farrar, S.B., Spirduso, W.W., Gilliam, P., Vaughn, D. & Wilcox, R.E. (1982) Tactile extinction: distinguishing between sensorimotor and motor asymmetries in rats with unilateral nigrostriatal damage. Pharmacol. Biochem. Behav., 16, 455-462.
31. Schneider, J.S., McLaughlin, W.W. & Roeltgen, D.P. (1992) Motor and non-motor behavioral deficits in monkeys made hemiparkinsonian by intracarotid MPTP infusion. Neurology, 42, 1565-1572.
32. Sellal, F., Hirsch, E., Lisovoski, F., Mutschler, V., Collard, M. & Marescaux, C. (1992) Contralateral disappearance of parkinsonian signs after subthalamic hematoma. Neurology, 42, 255-256.
33. Trépanier, L.L., Kumar, R., Lozano, A.M., Lang, A.E. & Saint-Cyr, J.A. (2000) Neuropsychological outcome of GPi pallidotomy and GPi or STN deep brain stimulation in Parkinson's Disease. Brain Cognition, 42, 324-347.
34. Voges, J., Volkmann, J., Allert, N., Lehrke, R., Koulousakis, A., Freund, H.J. & Strum, V. (2002) Bilateral high frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position. J. Neurosurg., 96, 269-279.
35. Windels, F., Bruet, N., Poupard, A., Urbain, N., Chouvet, G., Feuerstein, C. & Savasta, M. (2000) Effects of high frequency stimulation of subthalamic nucleus on extracellular glutamate and GABA in substantia nigra and globus pallidus in the normal rat. Eur. J. Neurosci., 12, 4141-4146.
36. Woods, S.P., Fields, J.A. & Troster, A.I. (2002) Neuropsychological sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a critical review. Neuropsychol. Rev., 12, 111-126.
37. Zadow, B. & Schmidt, W.J. (1994) Lesions of the entopeduncular nucleus and the subthalamic nucleus reduce dopamine receptor antagonist-induced catalepsy in the rat. Behav. Brain Res., 62, 71-79.