Chronological changes in electrolyte levels in arterial blood and bronchoalveolar lavage fluid in mice after exposure to an edemagenic gas

Inhalation Toxicology

Volumn 15, Issue 7, 2003, Pages 663-674

  Sciuto, Alfred M ^a   Carpin, Laura B ^a   Moran, Ted S ^a   Forster, Jeffry S ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CHLORIDE ION; ELECTROLYTE; PHOSGENE; POTASSIUM ION; SODIUM ION;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL BLOOD; ARTICLE; CHRONOLOGY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROLYTE BLOOD LEVEL; GAS PERMEABILITY; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALIA; VERTEBRATA;

EID: 0041758461     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370390197308     Document Type: Article

References (26)

1. Borak, J., and Diller, W. F. 2000. Phosgene exposure: Mechanisms of injury and treatment strategies. J. Occup. Environ. Med. 43:110-119.
2. Borok, Z., Liebler, J. M., Lubman, R. L., Foster, M., Zhou, B., Li, X., Zabski, S. M., Kwang-Jin, K., and Crandall, E. D. 2002. Na transport proteins are expressed by rat alveolar epithelial type I cells. Am. J. Physiol. Lung Cell Mol. Physiol. 282:L599-L608.
3. Brown, J. E., and Birky, M. M. 1980. Phosgene in the thermal decomposition products of polyvinyl chloride: Generation, detection and measurement. J. Anal. Toxicol. 4:166-174.
4. 2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria. Free Rad. Biol. Med. 18(3):479-486.
5. Cohen, J. J. 1979. Disorders of potassium balance. Hosp. Pract. (The Kidney in Health and Disease: VII), January.
6. Cucinell, S. A. 1974. Review of the toxicity of long-term phosgene exposure. Arch. Environ. Health 28:272-275.
7. Currie, W. D., Hatch, G. E., and Frosolono, M. F. 1987. Changes in lung ATP concentration in the rat after low-level phosgene exposure. J. Biochem. Toxicol. 2:105-114.
8. Duniho, S. M., Martin, J., Forster, J. S., Cascio, M. B., Moran, T. S., Carpin, L. B., and Sciuto, A. M. 2002. Acute pulmonary changes in mice exposed to phosgene. Toxicol. Pathol. 30(3):339-349.
9. Endres, D. B., and Rude, R. K. 1994. Mineral and bone. In Tietz textbook of clinical chemistry, eds. C. A. Burtis and E. R. Ashwood, 2nd ed., pp. 1887-1973. Philadelphia: W. B. Saunders.
10. Frosolono, M. F., and Pawlowski, R. 1977. Effect of phosgene on rat lungs after single high-level exposure: I. Biochemical alterations. Arch. Environ. Health 32:271-277.
11. Institute of Laboratory Animal Science. 1996. Guide for the care and use of laboratory animals. Washington, DC: National Research Council.
12. Krajewski, J. A. 1997. Chemical accidents and catastrophies as a source of the greatest hazard to the environment and human health. Med. Pr. 48:93-103.
13. Kutchai, H. C. 1998. Cellular physiology. In Physiology, eds. R. M. Berne and M. N. Levy, 4th ed., pp. 3-77. St. Louis, MO: Mosby.
14. Mairbäurl, H., Mayer, K., Kwang-Jin, K., Borok, Z., Bartsch, P., and Crandall, E. D. 2002. Hypoxia decreases active Na transport across primary alveolar epithelial cell monolayers. Am. J. Physiol. Lung Cell Mol. Physiol. 282:L659-L665.
15. Matthay, M. 2002. Regulation of ion and fluid transport across the distal epithelia: New insights. Am. J. Physiol. Lung Cell. Mol. Physiol. 282:L595-L598.
16. National Institute of Occupational Safety and Health. 1993. Criteria for a recommended standard: Occupational exposure to phosgene. Publication 76137. Washington, DC: NIOSH.
17. Reid, F. M., Sciuto, A. M., Truxall, J. A., Neimuth, N., Vesely, K. R., and Stotts, R. R. 2002. A 72-hour anesthetized, ventilated swine model to assess efficacy of treatments for respiratory casualties. Biosci. Proc. III:1387-1397.
18. Rorison, D. G., and McPherson, S. J. 1992. Acute toxic inhalations. Emerg. Med. Clin. North Am. 10(2):409-435.
19. Schelble, D. T. 1990. Phospine and phosgene. In Clinical management of poisoning and drug overdose, eds. L. M. Haddad and J. F. Winchester, 2nd ed., pp. 1235-1240. Philadelphia: W. B. Saunders.
20. Sciuto, A. M. 1998. Assessment of early acute lung injury in rodents exposed to phosgene. Arch. Toxicol. 72:283-288.
21. Sciuto, A. M., Stotts, R. R., Chittenden, V., Choung, E., and Heflin, M. D. 1996. Changes in absorbance at 413 nm in plasma from three rodent species exposed to phosgene. Biochem. Biophys. Res. Commun. 226:906-911.
22. Sciuto, A. M., Moran, T. S., Narula, A., and Forster, J. S. 2001. Disruption of gas exchange in mice following exposure to the chemical threat agent phosgene. Mil. Med. 160:809-814.
23. Sciuto, A. M., Cascio, M. B., Moran, T. S., and Forster, J. S. 2002. Temporal changes in bronchoalveolar lavage fluid (BALF) antioxidant enzymes in mice with toxic gas-induced acute lung injury. Inhal Toxicol.
24. Stanton, B. A., and Koeppen, B. M. 1998. The kidney. In Physiology, eds. R. M. Berne and M. N. Levy, 4th ed., pp. 667-776. St. Louis, MO: Mosby.
25. Suzuki, Y. J., Forman, H. J., and Sevanian, A. 1997. Oxidants as stimulators of signal transduction. Free Radical Biol. Med. 22(1/2):269-285.
26. Tietz, N. W., Pruden, E. L., and Siggaard-Andersen, O. 1994. Electrolytes. In Tietz textbook of clinical chemistry, eds. C. A. Burtis and E. R. Ashwood, 2nd ed., pp. 1354-1374. Philadelphia: W. B. Saunders.