Nicorandil: A drug for many purposes: Too good to be true?

European Heart Journal

Volumn 24, Issue 14, 2003, Pages 1282-1284

  Eeckhout, Eric ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; NICORANDIL; PROPRANOLOL; TETROFOSMIN TC 99M;

DRUG CLASSIFICATION; DRUG EFFICACY; DRUG MECHANISM; EDITORIAL; HEART PROTECTION; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; ISCHEMIC HEART DISEASE; PRIORITY JOURNAL; SCINTIGRAPHY; ST SEGMENT; STABLE ANGINA PECTORIS;

ANGINA PECTORIS; CARDIOMYOPATHY, HYPERTROPHIC; HUMANS; MYOCARDIAL ISCHEMIA; NICORANDIL; VASODILATOR AGENTS;

EID: 0041743805     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-668X(03)00318-X     Document Type: Editorial

References (7)

1. Taira N. Nicorandil as a hybrid between nitrates and potassium channel activators. J Cardiol 1989;63:18-24.
2. The IONA study group. Effect of nicorandil coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial. Lancet 2002;359: 1269-75.
3. Matsuo H, Watanabe S, Segawa T et al. Evidence of pharmacological preconditioning during PTCA by intravenous pretreatment with ATP-sensitive K+channel opener nicorandil. Eur Heart J 2003;24:1296-303.
4. Izawa H, Iwase M, Takeichi Y et al. Effect of nicorandil on left ventricular end-diastolic pressure during excercise in patients with hypertrophic cardiomyopathy. Eur Heart J 2003;24:1340-8.
5. Matsuba T, Minatoguchi S, Matsuo H. Three minutes, but not one minutes ischemia and nicorandil have a preconditioning effect in patients with coronary artery disease. J Am Coll Cardiol 2000;35:345-51.
6. Takeichi Y, Yokota M, Iwase M et al. Biphasic changes in left ventricular end-diastolic pressure during dynamic exercise in patients with nonobstructive hypertrophic cardiomyopathy. J Am Coll Cardiol 2001;38:335-43.
7. De Bruyne B, Hersbach F, Pijls N et al. Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but "normal" coronary angiography. Circulation 2001; 104:2401-6.