Effect of linezolid on the phagocytic functions of human polymorphonuclear leukocytes

Chemotherapy

Volumn 49, Issue 4, 2003, Pages 163-166

  Ballesta, Sofía ^a   Pascual, Álvaro ^a   García, Isabel ^a   Perea, Evelio J ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Hydrogen peroxide radicals; Linezolid; Phagocytosis; Superoxide radicals

Indexed keywords

HYDROGEN PEROXIDE; LINEZOLID; LY 211397; SUPEROXIDE; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; CELL FUNCTION; ENTEROCOCCUS FAECALIS; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ACETAMIDES; ANTI-BACTERIAL AGENTS; BLOOD BACTERICIDAL ACTIVITY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCOCCUS FAECALIS; HUMANS; HYDROGEN PEROXIDE; METHICILLIN RESISTANCE; NEUTROPHILS; OXAZOLIDINONES; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS; SUPEROXIDES; VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 0041742249     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071139     Document Type: Article

References (22)

1. Pallister CJ, Lewis RJ: Effects of antimicrobial drugs on human neutrophil-microbe interactions. Br J Biomed Sci 2000;57:19-27.
2. Daschner FD: Antibiotics and host defence with special reference to phagocytosis by human polymorphonuclear leukocytes. J Antimicrob Chemother 1985;16:390-396.
3. Pascual A, Tsukayama D, Kovarik J, Gekker G, Peterson PK: Uptake and activity of rifapentine in human peritoneal macrophages and polymorphonuclear leukocytes. Eur J Clin Microbiol 1987;6:152-157.
4. Pascual A, García I, Perea EJ: Fluorometric measurement of ofloxacin by human polymorphonuclear leukocytes. Antimicrob Agents Chemother 1989;33:653-656.
5. Elliot GR, Peterson PK, Verbrugh HA, Freiberg MR, Hoidal JR, Quie PG: Influence of subinhibitory concentrations of penicillin, cephalotin and clindamycin on Staphylococcus aureus growth in human phagocytic cells. Antimicrob Agents Chemother 1982;22:781-784.
6. Veringa EM, Verhoef J: Clindamycin at subinhibitory concentrations enhances antibody- and complement-dependent phagocytosis by human polymorphonuclear leukocytes of Staphylococcus aureus. Chemotherapy 1987;33:243-249.
7. Zurenko GE, Gibson JK, Shinabarger DL, Aristoff PA, Ford CW, Yarpley WG: Oxazolidinones: A new class of antibacterials. Curr Opin Pharmacol 2001;1:470-476.
8. Picazo JJ, Betriu C: Microorganismos grampositivos multirresistentes. Rev Exp Quimioter 2002;15:3-10.
9. Diekema DJ, Jones RN: Oxazolidinone antibiotics. Lancet 2001;358:1975-1982.
10. Clemett D, Marrkam A: Linezolid. Drugs 2000;59:815-827.
11. National Committee for Clinical Laboratory Standards: Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, ed 5. Approved Standard. Villanova, NCCLS, 2000.
12. Peterson PK, Verhoef J, Schmeling D, Quie PG: Kinetics of phagocytosis and bacterial killing by human polymorphonuclear leukocytes and monocytes. J Infect Dis 1997;136:502-509.
13. 3H]-thymidine-labelled bacteria. J Immunol Methods 1997;14:303-311.
14. Pick E, Mizel D: Rapid microassay for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader. J Immunol Methods 1981;46:211-226.
15. Lowry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
16. Pascual A, Ballesta S, García I, Perea EJ: Uptake and intracellular activity of linezolid in human phagocytic and non-phagocytic cells. Antimicrob Agents Chemother 2002;46:4013-4015.
17. Messick CR, Rodvold KA, Pendland SL: Modified time-kill assay against multidrug-resistant Enterococcus faecium with novel antimicrobial combinations. J Antimicrob Chemother 1999;44:831-834.
18. Herrera I, Jacques K, Murray B, Rakita R: The effect of antibiotic exposure on adherence to neutrophils of Enterococcus faecium resistant to phagocytosis. J Antimicrob Chmotherapy 1997;39(A):109-113.
19. Pascual A, Conejo MC, López López G, Perea EJ: Effect of ampicillin/sulbactam on human polymorphonuclear leukocyte function. Chemotherapy 1991;37:335-342.
20. Ballesta S, Pascual A, García I, Conejo C, Perea EJ: Effect of five fluoroquinolones on the bactericidal activity of human polymorphonuclear leukocytes against Staphylococcus aureus. Enferm Infecc Microbiol Clin 1996;14:600-603.
21. Aquilini D, Bartoloni A, Paradisi F: Influence of teicoplanin on the chemiluminescence of phagocytosing human granulocytes. J Chemother 1991;3:119-121.
22. Abdelgahffar H, Kirst H, Soukri A, Babin-Chevaye C, Labro MT: Structure-activity relationships among 9-N-alkyl derivates of erythromycylamine and their effect on the oxidative burst of human neutrophils in vitro. J Chemother 2002;14:132-139.