메뉴 건너뛰기




Volumn 9, Issue 5, 2003, Pages 374-377

Troponin levels as a guide to treatment of pulmonary embolism

Author keywords

Pulmonary embolism; Troponin I; Troponin T

Indexed keywords

FIBRINOLYTIC AGENT; TROPONIN; TROPONIN C; TROPONIN I; TROPONIN T;

EID: 0041737618     PISSN: 10705287     EISSN: None     Source Type: Journal    
DOI: 10.1097/00063198-200309000-00006     Document Type: Review
Times cited : (25)

References (37)
  • 1
    • 0033851515 scopus 로고    scopus 로고
    • Myocardial infarction redefined: A consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction
    • Alpert JS, Thygesen K, Antman E, Bassand JP: Myocardial infarction redefined: a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000, 36:959-969.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 959-969
    • Alpert, J.S.1    Thygesen, K.2    Antman, E.3    Bassand, J.P.4
  • 2
    • 0042637465 scopus 로고
    • Treatment of acute PE
    • Edited by Braunwald E, Goldhaber SZ. Philadelphia: Current Medicine
    • Goldhaber SZ: Treatment of acute PE. In Atlas of Heart Disease, vol. 3. Edited by Braunwald E, Goldhaber SZ. Philadelphia: Current Medicine; 1995.
    • (1995) Atlas of Heart Disease , vol.3
    • Goldhaber, S.Z.1
  • 3
    • 0026577798 scopus 로고
    • The clinical course of pulmonary embolism
    • Carson JL, Kelley MA, Duff A, et al.: The clinical course of pulmonary embolism. N Engl J Med 1992, 326:1240-1245.
    • (1992) N Engl J Med , vol.326 , pp. 1240-1245
    • Carson, J.L.1    Kelley, M.A.2    Duff, A.3
  • 4
    • 0026646402 scopus 로고
    • Optimum duration of anticoagulation for deep-vein thrombosis and pulmonary embolism
    • Research Committee of the British Thoracic Society: Optimum duration of anticoagulation for deep-vein thrombosis and pulmonary embolism. Lancet 1992, 340:873-876.
    • (1992) Lancet , vol.340 , pp. 873-876
  • 5
    • 0017316856 scopus 로고
    • Mortality in patients treated for pulmonary embolism
    • Alpert JS,Smith R, Carlson J et al.: Mortality in patients treated for pulmonary embolism. JAMA 1976, 236:1477-1480.
    • (1976) JAMA , vol.236 , pp. 1477-1480
    • Alpert, J.S.1    Smith, R.2    Carlson, J.3
  • 6
    • 0030588517 scopus 로고    scopus 로고
    • Cardiovascular risk stratification of pulmonary embolism
    • Cannon CP, Goldhaber SZ: Cardiovascular risk stratification of pulmonary embolism. Am J Cardiol 1996, 78;1149-1151.
    • (1996) Am J Cardiol , vol.78 , pp. 1149-1151
    • Cannon, C.P.1    Goldhaber, S.Z.2
  • 7
    • 0030779281 scopus 로고    scopus 로고
    • Management strategies and determinants of outcome in acute major pulmonary embolism: Results of a multicenter registry
    • Kasper W, Konstantinides S, Geibel A, et al.: Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol 1997, 30:1165-1171.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1165-1171
    • Kasper, W.1    Konstantinides, S.2    Geibel, A.3
  • 8
    • 0343517175 scopus 로고    scopus 로고
    • Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism
    • Giannitsis E, Muller-Bardorff M, Kurowski V, et al.: Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation 2000, 102:211-217. Fifty-six confirmed PE patients were enrolled prospectively in this study to evaluate the prognostic value of troponin T levels. This was one of the first studies to show that increased troponin T levels were associated independently with mortality as well as prolonged hypotension, shock, and need for subsequent resuscitation. This study lends credence to the presumption that cardiac troponin levels may be used to stratify PE patients by risk.
    • (2000) Circulation , vol.102 , pp. 211-217
    • Giannitsis, E.1    Muller-Bardorff, M.2    Kurowski, V.3
  • 9
    • 0035930101 scopus 로고    scopus 로고
    • Ability of minor elevations of troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and non-ST elevation myocardial infarction: Results from a randomized trial
    • Morrow DA, Cannon CP, Rifai N, et al.: Ability of minor elevations of troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and non-ST elevation myocardial infarction: results from a randomized trial. JAMA. 2001, 286:2405-2412.
    • (2001) JAMA , vol.286 , pp. 2405-2412
    • Morrow, D.A.1    Cannon, C.P.2    Rifai, N.3
  • 10
    • 0037015227 scopus 로고    scopus 로고
    • Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism
    • Konstantinides S, Geibel A, Olschewski M, et al.: Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism. Circulation 2002, 106:1263-1268. Troponins were evaluated in 106 confirmed PE patients. Troponin level correlated with echocardiographic RVD, mortality, recurrent PE, and hospital course. This study adds strength to the argument that troponins can be used for risk stratification of APE patients.
    • (2002) Circulation , vol.106 , pp. 1263-1268
    • Konstantinides, S.1    Geibel, A.2    Olschewski, M.3
  • 11
    • 0030664975 scopus 로고    scopus 로고
    • Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I
    • Hamm CW, Goldmann BU, Heeschen C, et al.: Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 1997, 337:1648-1653.
    • (1997) N Engl J Med , vol.337 , pp. 1648-1653
    • Hamm, C.W.1    Goldmann, B.U.2    Heeschen, C.3
  • 12
    • 0027262650 scopus 로고
    • Cardiac troponin I: A marker with high specificity for cardiac injury
    • Adams JE III, Bodor GS, Davila-Roman VG, et al.: Cardiac troponin I: a marker with high specificity for cardiac injury. Circulation 1993, 88:101-106.
    • (1993) Circulation , vol.88 , pp. 101-106
    • Adams J.E. III1    Bodor, G.S.2    Davila-Roman, V.G.3
  • 13
    • 0034813110 scopus 로고    scopus 로고
    • Risk stratification using serum concentrations of cardiac troponin T in patients with end-stage renal disease on chronic maintenance dialysis
    • Ishii J, Nomura M, Okuma T, et al.: Risk stratification using serum concentrations of cardiac troponin T in patients with end-stage renal disease on chronic maintenance dialysis. Clin Chim Acta 2001, 312:69-79.
    • (2001) Clin Chim Acta , vol.312 , pp. 69-79
    • Ishii, J.1    Nomura, M.2    Okuma, T.3
  • 14
    • 0031757217 scopus 로고    scopus 로고
    • Troponin T, a predictor of death in chronic haemodialysis patients
    • Porter GA, Norton T, Bennett WB: Troponin T, a predictor of death in chronic haemodialysis patients. Eur Heart J 1998, 19:N34-N37.
    • (1998) Eur Heart J , vol.19
    • Porter, G.A.1    Norton, T.2    Bennett, W.B.3
  • 15
    • 0036271468 scopus 로고    scopus 로고
    • Cardiac troponin T levels are associated with poor short- and long-term prognosis in patients with acute cardiogenic pulmonary edema
    • Perna ER, Macin SM, Parras JI, et al.: Cardiac troponin T levels are associated with poor short- and long-term prognosis in patients with acute cardiogenic pulmonary edema. Am Heart J 2002, 143:814-820.
    • (2002) Am Heart J , vol.143 , pp. 814-820
    • Perna, E.R.1    Macin, S.M.2    Parras, J.I.3
  • 16
    • 0036238875 scopus 로고    scopus 로고
    • Cardiac troponin I release after severe envenoming by Tityus serrulatus
    • Cupo P, Hering SE. Cardiac troponin I release after severe envenoming by Tityus serrulatus. Toxicon 2002, 40:823-830.
    • (2002) Toxicon , vol.40 , pp. 823-830
    • Cupo, P.1    Hering, S.E.2
  • 17
    • 0035153071 scopus 로고    scopus 로고
    • Evidence of cardiac myolysis in severe nonischemic heart failure and the potential role of increased wall strain
    • Logeart D, Beyne P, Cusson C, et al.: Evidence of cardiac myolysis in severe nonischemic heart failure and the potential role of increased wall strain. Am Heart J 2001, 141:247-253.
    • (2001) Am Heart J , vol.141 , pp. 247-253
    • Logeart, D.1    Beyne, P.2    Cusson, C.3
  • 18
    • 0037074178 scopus 로고    scopus 로고
    • Elevated cardiac troponin levels in patients with submassive pulmonary embolism
    • Douketis JD, Crowther MA, Stanton EB, et al.: Elevated cardiac troponin levels in patients with submassive pulmonary embolism. Arch Intern Med 2002, 162:79-81.
    • (2002) Arch Intern Med , vol.162 , pp. 79-81
    • Douketis, J.D.1    Crowther, M.A.2    Stanton, E.B.3
  • 20
    • 0034847565 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition is associated with reduced troponin release in non-ST-elevation acute coronary syndromes
    • Kennon S, Barakat K, Hitman GA, et al.: Angiotensin-converting enzyme inhibition is associated with reduced troponin release in non-ST-elevation acute coronary syndromes. J Am Coll Cardiol 2001, 38:724-728.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 724-728
    • Kennon, S.1    Barakat, K.2    Hitman, G.A.3
  • 21
    • 0002337453 scopus 로고    scopus 로고
    • Diseases of the adrenal cortex
    • Edited by Fauci AS, Braunwald E, Isselbacher KJ, et al. New York: McGraw-Hill Health Profession Division
    • Williams GH, Dluly RG: Diseases of the adrenal cortex. In Harrison's Principles of Internal Medicine, edn 14. Edited by Fauci AS, Braunwald E, Isselbacher KJ, et al. New York: McGraw-Hill Health Profession Division; 1998:2035-2057.
    • (1998) Harrison's Principles of Internal Medicine, Edn 14 , pp. 2035-2057
    • Williams, G.H.1    Dluly, R.G.2
  • 22
    • 0036321393 scopus 로고    scopus 로고
    • Troponin T elevation in lobar lung disease
    • Jolobe OMP. Troponin T elevation in lobar lung disease [letter]. Postgrad Med J 2002, 78:443.
    • (2002) Postgrad Med J , vol.78 , pp. 443
    • Jolobe, O.M.P.1
  • 23
    • 0023919043 scopus 로고    scopus 로고
    • Acute right-ventricular infarction secondary to a massive pulmonary embolism
    • Coma-Canella I, Gamallo C, Martinez Onsurbe P, et al.: Acute right-ventricular infarction secondary to a massive pulmonary embolism. Eur Heart J 1998, 9:534-540.
    • (1998) Eur Heart J , vol.9 , pp. 534-540
    • Coma-Canella, I.1    Gamallo, C.2    Martinez Onsurbe, P.3
  • 24
    • 0036201449 scopus 로고    scopus 로고
    • Release kinetics of cardiac troponin T in survivors of confirmed severe pulmonary embolism
    • Muller-Bardorff M, Weidtmann B, Giannitsis E, et al.: Release kinetics of cardiac troponin T in survivors of confirmed severe pulmonary embolism. Clin Chem 2002, 48:673-675.
    • (2002) Clin Chem , vol.48 , pp. 673-675
    • Muller-Bardorff, M.1    Weidtmann, B.2    Giannitsis, E.3
  • 25
    • 0034332688 scopus 로고    scopus 로고
    • Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction
    • Meyer T, Binder L, Hruska N, et al.: Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol 2000, 36:1632-1636. Troponin levels were evaluated in 36 PE patients in this randomized, double-blind study. The authors found that 39% of these confirmed PE patients had an elevation in troponin I and that these patients were more likely to have more segmental defects on ventilation-perfusion lung scanning as well as right ventricular dilation by echocardiography.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1632-1636
    • Meyer, T.1    Binder, L.2    Hruska, N.3
  • 26
    • 0037425784 scopus 로고    scopus 로고
    • Cardiac troponin T in the severity assessment of patients with pulmonary embolism: Cohort study
    • Janata K, Holzer M, Laggner AN, et al.: Cardiac troponin T in the severity assessment of patients with pulmonary embolism: cohort study. BMJ 2003, 326:312-313.
    • (2003) BMJ , vol.326 , pp. 312-313
    • Janata, K.1    Holzer, M.2    Laggner, A.N.3
  • 27
    • 0028236892 scopus 로고
    • Prognostic significance of right ventricular hypokinesis and perfusion lung scan defects in pulmonary embolism
    • Wolfe MW, Lee RT, Feldstein ML, et al.: Prognostic significance of right ventricular hypokinesis and perfusion lung scan defects in pulmonary embolism. Am Heart J 1994, 127:1371-1375.
    • (1994) Am Heart J , vol.127 , pp. 1371-1375
    • Wolfe, M.W.1    Lee, R.T.2    Feldstein, M.L.3
  • 28
    • 0036743132 scopus 로고    scopus 로고
    • Diagnostic utility of cardiac troponin-I levels in patients with suspected pulmonary embolism
    • Dieter RS, Ernst E, Ende DJ, et al.: Diagnostic utility of cardiac troponin-I levels in patients with suspected pulmonary embolism. Angiology 2002, 53:583-585. Troponin I levels were evaluated in 91 patients suspected of having APE who also had VO scans. Elevated troponin I levels were not found to correlate with V/O scan results, nor were they deemed useful in the evaluation of suspected PE patients.
    • (2002) Angiology , vol.53 , pp. 583-585
    • Dieter, R.S.1    Ernst, E.2    Ende, D.J.3
  • 29
    • 0034691310 scopus 로고    scopus 로고
    • Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction
    • Grifoni S, Olivotto I, Cecchini P, et al.: Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction. Circulation 2000, 101:2817-2822. This study evaluated 209 patients with confirmed PE, finding that 31% had submassive PE. This subgroup had a high rate of subsequent shock (10%) and inhospital mortality (5%). Echocardiographic evidence of RVD in otherwise normotensive patients with APE was therefore shown to be a useful means to stratify these patients by risk. The authors concluded that these patients represent a group that may benefit from more aggressive therapies.
    • (2000) Circulation , vol.101 , pp. 2817-2822
    • Grifoni, S.1    Olivotto, I.2    Cecchini, P.3
  • 30
    • 0036928435 scopus 로고    scopus 로고
    • Troponin levels in acute pulmonary embolism
    • Pruszczyk P, Szulc M, Torbicki A: Troponin levels in acute pulmonary embolism. Chest 2002, 122:2264-2265.
    • (2002) Chest , vol.122 , pp. 2264-2265
    • Pruszczyk, P.1    Szulc, M.2    Torbicki, A.3
  • 31
    • 0033574235 scopus 로고    scopus 로고
    • Pulmonary embolism: One-year follow-up with echocardiography Doppler and five year survival analysis
    • Ribeiro A, Lindmarker P, Johnsson H, et al.: Pulmonary embolism: one-year follow-up with echocardiography Doppler and five year survival analysis. Circulation 1999, 99:1325-1330. This important study is the longest published follow-up of patients with PE evaluated for echocardiographic evidence of persistent pulmonary hypertension and survival. PE patients were found to be more likely to have persistent pulmonary hypertension if their initial pulmonary systolic pressures were more than 50 mmHg or if they were older than 70 years. Those who had persistent pulmonary hypertension and RVD at 6 weeks were also less likely to survive at 5 years' follow-up.
    • (1999) Circulation , vol.99 , pp. 1325-1330
    • Ribeiro, A.1    Lindmarker, P.2    Johnsson, H.3
  • 32
    • 0016154211 scopus 로고
    • Determinant of right ventricular function and haemodynamics after pulmonary embolism
    • McIntyre KM, Sasahara AA: Determinant of right ventricular function and haemodynamics after pulmonary embolism. Chest 1975, 65:534-543.
    • (1975) Chest , vol.65 , pp. 534-543
    • McIntyre, K.M.1    Sasahara, A.A.2
  • 33
    • 0033395867 scopus 로고    scopus 로고
    • Submassive and massive pulmonary embolism: A target for thrombolytic therapy?
    • Konstantinides S, Geibel A, Kasper W: Submassive and massive pulmonary embolism: a target for thrombolytic therapy? Thromb Haemost 1999, 82(suppl 1):104-108.
    • (1999) Thromb Haemost , vol.82 , Issue.1 SUPPL. , pp. 104-108
    • Konstantinides, S.1    Geibel, A.2    Kasper, W.3
  • 34
    • 0033104189 scopus 로고    scopus 로고
    • Recovery of regional right ventricular function after pulmonary embolism
    • Nass N, McConnell MV, Goldhaber SZ, et al.: Recovery of regional right ventricular function after pulmonary embolism. Am J Cardiol 1999, 83:804-806.
    • (1999) Am J Cardiol , vol.83 , pp. 804-806
    • Nass, N.1    McConnell, M.V.2    Goldhaber, S.Z.3
  • 35
    • 0027446870 scopus 로고
    • Alteplase versus heparin in acute pulmonary embolism: Randomized trial assessing right-ventricular function and pulmonary perfusion
    • Goldhaber SZ, Haire WD, Feldstein ML, et al. Alteplase versus heparin in acute pulmonary embolism: randomized trial assessing right-ventricular function and pulmonary perfusion. Lancet 1993, 341:507-511.
    • (1993) Lancet , vol.341 , pp. 507-511
    • Goldhaber, S.Z.1    Haire, W.D.2    Feldstein, M.L.3
  • 36
    • 0037057591 scopus 로고    scopus 로고
    • The management strategies and prognosis of pulmonary embolism-3 trial investigators. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism
    • Konstantinides S, Geibel A, Heusef G, et al.: The management strategies and prognosis of pulmonary embolism-3 trial investigators. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. N Engl J Med 2002, 347:1143-1150.
    • (2002) N Engl J Med , vol.347 , pp. 1143-1150
    • Konstantinides, S.1    Geibel, A.2    Heusef, G.3
  • 37
    • 0030742062 scopus 로고    scopus 로고
    • Association between thrombolytic treatment and the prognosis of hemodynamically stable patients with major pulmonary embolism: Results of a multicenter registry
    • Konstantinides S, Geibel A, Olschewski M, et al.: Association between thrombolytic treatment and the prognosis of hemodynamically stable patients with major pulmonary embolism: results of a multicenter registry. Circulation 1997, 96:882-888.
    • (1997) Circulation , vol.96 , pp. 882-888
    • Konstantinides, S.1    Geibel, A.2    Olschewski, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.