Dopamine receptor hetero-oligomerization in the pathogenesis of schizophrenia: Qualitative as opposed to quantitative notions of dopaminergic receptors [2]

Schizophrenia Research

Volumn 63, Issue 1-2, 2003, Pages 197-198

  Tsai, Shih Jen ^a   Hong, Chen Jee ^b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BENZAMIDE DERIVATIVE; CLOZAPINE; DOPAMINE RECEPTOR; RACLOPRIDE; SPIPERONE;

CLINICAL TRIAL; DOPAMINERGIC TRANSMISSION; HUMAN; LETTER; OLIGOMERIZATION; PATHOGENESIS; PREFRONTAL CORTEX; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SCHIZOPHRENIA; SYMPTOMATOLOGY;

EID: 0041706304     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(02)00436-X     Document Type: Letter

References (13)

1. Benes F.M. The role of stress and dopamine-GABA interactions in the vulnerability for schizophrenia. J. Psychiatr. Res. 31:1997;257-275.
2. Farde L., Wiesel F.A., Stone-Elander S., Halldin C., Nordstrom A.L., Hall H., Sedvall G. D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride. Arch. Gen. Psychiatry. 47:1990;213-219.
3. George S.R., Fan T., Xie Z., Tse R., Tam V., Varghese G., O'Dowd B.F. Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties. J. Biol. Chem. 275:2000;26128-26135.
4. Jordan B.A., Devi L.A. G-protein-coupled receptor heterodimerization modulates receptor function. Nature. 399:1999;697-700.
5. Jordan B.A., Trapaidze N., Gomes I., Nivarthi R., Devi L.A. Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation. Proc. Natl. Acad. Sci. U. S. A. 98:2001;343-348.
6. Laruelle M., Abi-Dargham A., van Dyck C.H., Gil R., D'Souza C.D., Erdos J., McCance E., Rosenblatt W., Fingado C., Zoghbi S.S., Baldwin R.M., Seibyl J.P., Krystal J.H., Charney D.S., Innis R.B. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc. Natl. Acad. Sci. U. S. A. 93:1996;9235-9240.
7. Ng G.Y., O'Dowd B.F., Lee S.P., Chung H.T., Brann M.R., Seeman P., George S.R. Dopamine D2 receptor dimers and receptor-blocking peptides. Biochem. Biophys. Res. Commun. 227:1996;200-204.
8. Rocheville M., Lange D.C., Kumar U., Patel S.C., Patel R.C., Patel Y.C. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science. 288:2000;154-157.
9. Rocheville M., Lange D.C., Kumar U., Sasi R., Patel R.C., Patel Y.C. Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers. J. Biol. Chem. 275:2000;7862-7869.
10. Salahpour A., Angers S., Bouvier M. Functional significance of oligomerization of G-protein-coupled receptors. Trends Endocrinol. Metab. 11:2000;163-168.
11. Vysokanov A., Flores-Hernandez J., Surmeier D.J. mRNAs for clozapine-sensitive receptors co-localize in rat prefrontal cortex neurons. Neurosci. Lett. 258:1998;179-182.
12. Wong D.F., Wagner H.N. Jr., Tune L.E., Dannals R.F., Pearlson G.D., Links J.M., Tamminga C.A., Broussolle E.P., Ravert H.T., Wilson A.A. Positron emission tomography reveals elevated D2 dopamine receptors in drug-naïve schizophrenics. Science. 234:1986;1558-1563.
13. Xie Z., Lee S.P., O'Dowd B.F., George S.R. Serotonin 5-HT1B and 5-HT1D receptors form homodimers when expressed alone and heterodimers when co-expressed. FEBS Lett. 456:1999;63-67.