Rapid access to cis 3-substituted prolines

Tetrahedron Letters

Volumn 44, Issue 35, 2003, Pages 6779-6780

  Pellegrini, Nadia ^a   Schmitt, Martine ^a   Bourguignon, Jean Jacques ^a  

^a Laboratoire de Pharmacochimie   (France)

Author keywords

Pd coupling; Peptidomimetics; Prolines

Indexed keywords

AMINO ACID; PALLADIUM; PROLINE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHIRALITY; CONFORMATIONAL TRANSITION; DIASTEREOISOMER; HYDROGENATION;

EID: 0041668197     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(03)01476-X     Document Type: Article

References (9)

1. Hirschmann R., Veber D.F. Bioorg. Chem. 7:1978;447.
2. Toniolo C. Int. J. Protein Res. 35:1990;287. and references cited therein.
3. Pellegrini N., Schmitt M., Guerry S., Bourguignon J.J. Tetrahedron Lett. 43:2002;3243-3246.
4. Kamenecka T.M., Park Y.J., Lin L.S., Lanza T., Hagmann W.K. Tetrahedron Lett. 42:2001;8571-8573.
5. Davis F.A., Fang T., Goswami R. Org. Lett. 4:2002;1599-1602.
6. 2-NHBoc), 4.8-7.0 (s, 1H, NH).
7. 2-NHBoc), 4.8-7.0 (s, 1H, NH).
8. 6-DMSO solution. This observation confirmed the presence of two isomers, but only one 2,3-cis diastereoisomer.
9. 2), 6.9 (d, 2H, Har.), 7.1-7.6 (m, 7H, Har.).