Analysis of DNA damage using the comet assay in infants fed cow's milk

Biology of the Neonate

Volumn 84, Issue 2, 2003, Pages 135-141

  Dündaröz, Ruşen ^b,f   Ulucan, Hakan ^a   Aydin, Halil Ibrahim ^b   Güngör, Tayfun ^c   Baltaci, Volkan ^d   Denli, Metin ^e   Sanisoǧlu, Yavuz ^b  

^a ADNAN MENDERES UNIVERSITY   (Turkey)

^b GULHANE SCHOOL OF MEDICINE   (Turkey)

^c Neonatal Intensive Care Unit   (Turkey)

^d BASKENT UNIVERSITY   (Turkey)

^e ANKARA MEVKI MILITARY HOSPITAL   (Turkey)

^f NONE   (Turkey)

Author keywords

Breast feeding; Carcinogenesis; Childhood malignancy; Comet assay; Cow's milk; DNA damage; Infant nutrition

Indexed keywords

DNA;

ARTICLE; BREAST MILK; CANCER GROWTH; CANCER SUSCEPTIBILITY; CELL ASSAY; COMET ASSAY; CONTROLLED STUDY; DISEASE COURSE; DNA DAMAGE; DNA DETERMINATION; FEMALE; HUMAN; HUMAN CELL; INFANT; INFANT FEEDING; LYMPHOCYTE; MALE; MILK; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANIMALS; BREAST FEEDING; CATTLE; COMET ASSAY; DNA DAMAGE; FEMALE; HUMANS; INFANT; INFANT NUTRITION PHYSIOLOGY; MALE; MILK; NEOPLASMS;

EID: 0041660799     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071947     Document Type: Article

References (29)

1. Howard CR, Lawrence RA: Breast-feeding and drug exposure. Obstet Gynecol Clin North Am 1998;25:195-217.
2. Villalpando S, Hamosh M: Early and late effects of breast-feeding: Does breast-feeding really matter? Biol Neonate 1998;74:177-191.
3. Schwartzbaum JA, George SL, Pratt CB, Davis B: An exploratory study of environmental and medical factors potentially related to childhood cancer. Med Pediatr Oncol 1991;19:115-121.
4. Davis MK: Review of the evidence for an association between infant feeding and childhood cancer. Int J Cancer 1998;11(suppl):29-33.
5. Nichols KE, Frederick PL, Haber DA, Diller L: Childhood cancer predisposition: Applications of molecular testing and future implications. J Pediatr 1998;132:389-397.
6. Freudenheim JL, Marshall JR, Graham S, Laughlin R, Vena JE, Bandera E, Muti P, Swanson M, Nemeto T: Exposure to breast milk in infancy and the risk of breast cancer. Epidemiology 1994;5:324-331.
7. Shu XO, Linet MS, Steinbuch M, Wen WQ, Buckley JD, Neglia JP, Potter JD, Reaman GH, Robison LL: Breast-feeding and risk of childhood acute leukemia. J Natl Cancer Inst 1999;91:1765-1772.
8. Fairbairn DW, Olive PL, O'Neill KL: The comet assay: A comprehensive review. Mutat Res 1995;339:37-59.
9. Singh NP, McCoy MT, Tice RR, Schneider EL: A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-191.
10. Baltaci V, Aygün N, Akyol D, Karakaya AE, Şardaş S: Chromosomal aberrations and alkaline comet assay in families with habitual abortion. Mutat Res 1998;417:47-55.
11. Zar JH: Biostatistical Analysis, ed 3. Englewood Cliffs, Prentice-Hall, 1996, pp 317-353.
12. Dündaröz R, Aydin HI, Ulucan H, Baltaci V, Denli M, Gökçay E: A preliminary study on DNA damage in infants not breast-fed. Pediatr Int 2002;44:127-130.
13. Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
14. Petridou E, Trichopulos D, Kalapothaki V, Pourtsidis A, Kogevinas M, Kalmanti M, Koliouskas D, Kosmidis H, Panagiotou JP, Piperopoulou F, Tzortzatou: The risk profile of childhood leukaemia in Greece: A nation-wide case-control study. Br J Cancer 1997;76:1241-1247.
15. Fleshner NE, Kucuk O: Antioxidant dietary supplements: Rationale and current status as chemopreventive agents for prostate cancer. Urology 2001;57(suppl 1):90-94.
16. Pool-Zobel BL, Bub A, Müller H, Wollowski I, Rechkemmer G: Consumption of vegetables reduces genetic damage in humans: First results of a human intervention trial with carotenoid-rich foods. Carcinogenesis 1997;18:1847-1850.
17. Jochum F, Fuchs A, Menzel H, Lombeck I: Selenium in German infants fed breast milk or different formulas. Acta Paediatr 1995;84:859-862.
18. Sommerburg O, Meissner K, Nelle M, Lenhartz H, Leichsenring M: Carotenoid supply in breast-fed and formula-fed neonates. Eur J Pediatr 2000;159:86-90.
19. Glinghammar B, Venturi M, Rowland IR, Rafter JJ: Shift from a dairy product-rich to a dairy product-free diet: Influence on cytotoxicity and genotoxicity of fecal water - potential risk factors for colon cancer. Am J Clin Nutr 1997;66:1277-1282.
20. Weisburger JH, Rivenson A, Garr K, Aliaga C: Tea, or tea and milk, inhibit mammary gland and colon carcinogenesis in rats. Cancer Lett 1997;114:323-327.
21. Tsuru S, Shinomiya N, Taniguchi M, Shimazaki H, Tanigawa K, Nomoto K: Inhibition of tumor growth by dairy products. J Clin Lab Immunol 1988;25:177-183.
22. Wollowski I, Seung-Taek J, Bakalinsky AT, Neudecker C, Pool-Zobel BL: Bacteria used for the production of yoghurt inactivate carcinogens and prevent DNA damage in the colon of rats. J Nutr 1999;129:77-82.
23. Udall JN, Suskind RM: Cow's milk versus formula in older infants: Consequences for human nutrition. Acta Paediatr 1999;430(suppl):61-67.
24. Berg HE, Van Boekel MAJS, Jongen WMF: Heating milk: A study on mutagenicity. J Food Sci 1990;55:1000-1003.
25. McKelvey-Martin VJ, Green MHL, Schmezer P, Pool-Zobel BL, De Méo MP, Collins A: The single cell gel electrophoresis assay (comet assay): A European review. Mutat Res 1993;288:47-63.
26. Betti C, Davini T, Giannessi L, Loprieno N, Barale R: Microgel electrophoresis assay (comet test) and SCE analysis in human lymphocytes from 100 normal subjects. Mutat Res 1994;307:323-333.
27. Hartmann A, Plappert U, Raddatz K, Grunert-Fuchs M, Speit G: Does physical activity induce DNA damage? Mutagenesis 1994;9:269-272.
28. MacCarthy PJ, Sweetman SF, McKenna PG, McKelvey-Martin VJ: Evaluation of manual and image analysis quantification of DNA damage in the alkaline comet assay. Mutagenesis 1997;12:209-214.
29. Andreoli C, Leopardi P, Rossi S, Crebelli R: Processing of DNA damage induced by hydrogen peroxide and methyl methanesulfonate in human lymphocytes: Analysis by alkaline single cell gel electrophoresis and cytogenetic methods. Mutagenesis 1999;14:497-503.