Synthesis of 5-substituted 4,4-disubstituted 2-cyclohexen-1-ones by electro-generated base promoted Michael addition of 4,4-disubstituted 2,5-cyclohexadien-1-ones

Synlett

Volumn , Issue 6, 1998, Pages 599-600

  Torii, Sigeru ^a   Hayashi, Naoya ^a   Kuroboshi, Manabu ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0041572925     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1752     Document Type: Article

References (4)

1. Parker, K. A.; Kang, S.-A. J. Org. Chem. 1980, 45, 1218.
2. 2) at -40 °C to give the products 1a and 1b in 98% and 80% yields, respectively. (Chemical Equation Presented) 6a (R = Me) 1a (R = Me) 98% 6b (R = allyl) 1b (R = allyl) 80%
3. 1 pointed out that C,O-double Michael adduct 3a was obtained by use of EtONa/EtOH, whereas C,C-double adduct was afforded when NaH/THF was used.
4. Nilsson, A.; Palmquist, U.; Pettersson, T.; Ronlán, A. J. Chem. Soc., Perkin Trans. I. 1978, 708.