Fixed-dose fluticasone-salmeterol combination: At least effective and better tolerated than open-dose combinations;Association fixe fluticasone-salmétérol: Au moins aussi efficace et mieux acceptée par les patients asthmatiques que les associations libres

Revue de Pneumologie Clinique

Volumn 59, Issue 3, 2003, Pages 139-148

  Martinat, Y ^a   Desfougeres J L ^b  

^a Centre Medical Parot   (France)

^b GLAXOSMITHKLINE   (France)

Author keywords

Adult; Asthma; Combination therapy; Fluticasone; Salmeterol

Indexed keywords

BECLOMETASONE DIPROPIONATE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CORTICOSTEROID; FLUNISOLIDE; FLUTICASONE; SALMETEROL;

ADULT; AGED; ARTICLE; ASTHMA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; ALBUTEROL; ANDROSTADIENES; ASTHMA; BRONCHODILATOR AGENTS; DRUG COMBINATIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; RESPIRATORY FUNCTION TESTS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 0041563749     PISSN: 07618417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. NHLBI/WHO. Global strategy for asthma management and prevention. NHLBI/WHO workshop. Bethesda: National Institute of Health, 2002:176 p. www.ginasthma.com
2. Vollmer WM, Markson LE, O'Connor E, Sanocki LL, Fitterman L, Berger M, et al. Association of asthma control with health care utilization and quality of life. Am J Respir Crit Care Med 1999;60:1647-52.
3. Shrewsbury S, Pyke S, Britton M. Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA). BMJ 2000;320:568-75.
4. Pyke SD, Frith L, Drake F, Sykes J, Shah T. Synergy between fluticasone propionate and salmeterol from a single combination inhaler (Advair Seretide) vs delivery via separate inhalers. Am J Respir Crit Care Med 2001;163:D31.
5. Eickelberg O, Roth M, Lörx R, Bruce V, Rüdiger J, Johnson M, et al. Ligand-independent activation of the glucocorticoid receptor by β2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J Biol Chem 1999;274:1005-10.
6. Devillier P. Bronchodilatateurs bêta-adrénergiques et corticoïdes: complémentarité ou synergie d'action. Rev Fr Allergol Immunol Clin 2001;41:620-3.
7. Markham A, Jarvis J. Inhaled salmeterol/fluticasone propionate combination. A review of its use in persistent asthma. Drugs 2000;60:1207-33.
8. Bateman ED, Britton M, Carrilo J, Almeida J, Wixon C. Salmeterol/fluticasone combination inhaler. A new, effective and well-tolerated treatment for asthma. Clin Drug Invest 1998;16:193-201.
9. Chapman KR, Ringdal N, Backer V, Palmqvist M, Saarelainen S, Briggs M. Salmeterol and fluticasone propionate (50/250 μg) administered via combination Diskus inhaler is as effective as when given via separate Diskus inhalers. Can Respir J 1999;6:45-51.
10. Aubier M, Pieters WR, Schlosser NJJ, Steinmetz KO. Salmeterol/fluticasone propionate (50/500 μg) in combination in a Diskus® inhaler (Seretide®) is effective and safe in the treatment of steroid-dependent asthma. Respir Med 1999;93:876-84.
11. Freemantle N, Drummond M. Should clinical trials with concurrent economic analyses be blinded? JAMA 1997;7:82-4.
12. Bateman ED, Frith LF, Braunstein GL. Achieving guideline-based asthma control: does the patient benefit? Eur Respir J 2002;20:588-95.
13. Boulet LP, Becker A, Bérubé D, Beveridge R, Ernst P, on behalf of the Canadian Asthma Consensus Group. Canadian asthma consensus report, 1999. Can Med Assoc J 1999;161(11 Suppl).
14. Cochrane GM, Horne R, Chanez P. Compliance in asthma. Respir Med 1999;93:763-9.
15. Mahajan P, Okamoto L. Patient satisfaction with the Diskhaler and the Diskus inhaler, a new multidose powder delivery system for the treatment of asthma. Clin Ther 1997;19:1126-34.
16. Van der Palen J, Klein JJ, Schildkamp M. Comparison of a new multidose powder inhaler (Diskus®/Accuhaler®) and the Turbuhaler® regarding preference and ease of use. J Asthma 1998;35:147-52.