Pancreatic regeneration after ethionine-induced acute pancreatitis in rats lacking pancreatic CCK-A receptor gene expression

Journal of Gastroenterology

Volumn 38, Issue 7, 2003, Pages 672-680

  Sato, Takaya ^a   Niikawa, Junichi ^a   Usui, Ichiro ^a   Imamura, Tsunao ^a   Yoshida, Hitoshi ^a   Tanaka, Shigeki ^a   Mitamura, Keiji ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CCK A receptor; Cholecystokinin (CCK); Ethionine induced pancreatitis; OLETF rats

Indexed keywords

CHOLECYSTOKININ; CHOLECYSTOKININ RECEPTOR; DNA; ETHIONINE; PROTEIN;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CHOLECYSTOKININ BLOOD LEVEL; CONTROLLED STUDY; DNA CONTENT; GENE EXPRESSION; HISTOPATHOLOGY; INFLAMMATION; MALE; NONHUMAN; ORGAN WEIGHT; PANCREAS HEMORRHAGE; PANCREAS NECROSIS; PRIORITY JOURNAL; PROTEIN RESTRICTION; RAT; RAT STRAIN; TISSUE REGENERATION; TISSUE REPAIR;

ANIMALS; CHOLECYSTOKININ; DNA; ETHIONINE; GENE EXPRESSION; MALE; PANCREAS; PANCREATITIS, ACUTE NECROTIZING; PROTEINS; RATS; RATS, INBRED OLETF; RECEPTOR, CHOLECYSTOKININ A; RECEPTORS, CHOLECYSTOKININ; REGENERATION;

EID: 0041561143     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00535-003-1120-0     Document Type: Article

References (38)

1. Kawano K, Hirashima T, Mori S, Saitoh Y, Kurosumi M, Natori T. Spontaneous long-term hyperglycemic rat with diabetic complications. Diabetes 1992;41:1422-8.
2. Funakoshi A, Miyasaka K, Jimi A, Kawanami T, Takata Y, Kono A. Little or no expression of the cholecystokinin-A receptor gene in the pancreas of diabetic rats (Otsuka Long-Evans Tokushima Fatty = OLETF rats). Biochem Biophys Res Common 1994;199: 482-8.
3. Funakoshi A, Miyasaka K, Shinozaki H, Masuda M, Kawanami T, Takata Y, et al. An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor. Biochem Biophys Res Commun 1995;210:787-96.
4. Tachibana I, Akiyama T, Kanagawa K, Shirohara H, Furumi K, Watanabe N, et al. Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats. Am J Physiol 1996;270:G730-7.
5. Mainz DL, Black O, Webster PD. Hormonal control of pancreatic growth. J Clin Invest 1973;52:2300-4.
6. Morisset J, Guan D, Jurkowska G, Rivard N, Green GM. Endogenous cholecystokinin, the major factor responsible for dietary protein-induced pancreatic growth. Pancreas 1992;7:522-9.
7. Jurkowska G, Grondin G, Massé S, Morisset J. Soybean trypsin inhibitor and cerulein accelerate recovery of cerulein-induced pancreatitis in rats. Gastroenterology 1992;102:550-62.
8. Niederau C, Niederau M, Lüthen R, Strohmeyer G, Ferrell LD. Pancreatic exocrine secretion in acute experimental pancreatitis. Gastroenterology 1990;99:1120-7.
9. Niikawa J, Shin S, Omachi H, Ohta H, Takayama H, Kawada T, et al. Study on regeneration of pancreatic acinar cells in the rat pancreatitis induced by two doses Of DL-ethionine (in Japanese with English abstract). J Jpn Panc Soc 1987;2:30-8.
10. Niikawa J, Shin S, Omachi H, Kawada T, Takayama H, Nakano I, et al. Study on pancreatic degeneration and regeneration in the rat pancreatic damage induced by two doses Of DL-ethionine (in Japanese with English abstract). J Jpn Panc Sco 1987;2:512-24.
11. Tani S, Okabayashi Y, Nakamura T, Fujii M, Itoh H, Otsuki M. Effect of a new cholecystokinin receptor antagonist loxiglumide on acute pancreatitis in two experimental animal models. Pancreas 1990;5:284-90.
12. Hashimura E, Shimizu F, Nishino T, Imagawa K, Tateishi K, Hamaoka T. Production of rabbit antibody specific for aminoterminal residues of cholecystokinin octapeptide (CCK-8) by selective suppression of cross-reactive antibody response. J Immunol Methods 1982;55:375-87.
13. Schmidt G, Thannhauser SJ. A method for the determination of deoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues. J Biol Chem 1945;161:83-9.
14. Schneider WC. Phosphorus compounds in animal tissues: a comparison of methods for the estimation of nucleic acids. J Biol Chem 1946;64:747-51.
15. Burton K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J 1956;62:315-23.
16. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193: 265-75.
17. Fitzgerald PJ, Alvizouri M. Rapid restitution of the rat pancreas following acinar cell necrosis subsequent to ethionine. Nature 1952;170:929-30.
18. Wachstein M, Meisel E. Cellular changes accompanying the degenerative and regenerative phase of ethionine-induced pancreatic damage in the rat. Lab Invest 1953;2:253-60.
19. Kinney TD, Kaufman N, Klavins JV. Regeneration of pancreatic acini during ethionine administration. Arch Pathol 1955;60:639-43.
20. Herman L, Fitzgerald PJ. Restitution of pancreatic acinar cells following ethionine. J Cell Biol 1962;12:297-312.
21. Ishida K, Mizuno A, Zhu M, Sano T, Shima K. Which is the primary etiologic event in Otsuka Long-Evans Tokushima Fatty rats, a model of spontaneous non-insulin-dependent diabetes mellitus, insulin resistance, or impaired insulin secretion? Metabolism 1995;44:940-5.
22. Funakoshi A, Miyasaka K, Masuda M, Jimi A. Loss of the trophic effect of camostate on the pancreas and failure of cerulein to induce acute pancreatitis in a new rat model not expressing the CCK-A receptor gene (in Japanese with English abstract). J Jpn Panc Soc 1995;10:428-36.
23. Tachibana I, Shirohara H, Czako L, Akiyama T, Nakano S, Watanabe N, et al. Role of endogenous cholecystokinin and cholecystokinin-A receptors in the development of acute pancreatitis in rats. Pancreas 1997;14:113-21.
24. Lombardi B, Estes LW, Longnecker DS. Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol 1975;79:465-80.
25. Koike H, Steer ML, Meldolesi J. Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis. Am J Physiol 1982:242:G297-307.
26. Niederau C, Liddle RA, Ferrell LD, Grendell JH, Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. J Clin Invest 1986;78:1056-63.
27. Makovec F, Bani M, Cereda R, Chistè R, Revel L, Rovati LC, et al. Protective effect of CR1409 (cholecystokinin antagonist) on experimental pancreatitis in rats and mice. Peptides 1986;7:1159-64.
28. Otsuki M, Tani S, Okabayashi Y, Nakamura T, Fujii M, Fujisawa T, et al. Effect of a new cholecystokinin receptor antagonist CR1392 on caerulein-induced acute pancreatitis in rats. Pancreas 1989;4:237-43.
29. Tachibana I, Kataoka K, Imoto M, Umehara K, Sasaki T, Yorizumi H, et al. Effect of a new cholecystokinin antagonist KSG-504 on caerulein-incluced acute pancreatitis in rats (in Japanese with English abstract). J Jpn Panc Soc 1992;7:440-7.
30. Okumura Y, Bamba T, Shintani Y, Yoshioka U, Inoue H, Fujiyama Y, et al. Effect of KSG-504, a new synthetic cholecystokinin receptor antagonist on ethionine-induced acute pancreatitis in rats (in Japanese with English abstract). Jpn J Gastroenterol 1993;90:3032-40.
31. Zhu M, Noma Y, Mizuno A, Sano T, Shima K. Poor capacity for proliferation of pancreatic β-cells in Otsuka-Long-Evans-Tokushima Fatty rat: a model of spontaneous NIDDM. Diabetes 1996;45:941-6.
32. Couture Y, Dunnigan J, Morisset J. Stimulation of pancreatic amylase secretion and protein synthesis by insulin. Scand J Gastroenterol 1972;7:257-63.
33. Ohashi N, Isaji S, Kawarada Y, Mizumoto R, Hibasami H, Nakashima K. Effect of insulin treatment on the regeneration of the remnant pancreas after major pancreatectomy in dogs. Int J Pancreatol 1991;9:165-70.
34. Funakoshi A, Miyasaka K, Shinozaki H, Arita Y, Nakano I, Nawata H. Regulation of pancreatic exocrine function in Otsuka Long-Evans Tokushima Fatty (OLETF) rats without gene expression of cholecystokinin-A receptor. Intern Med 1996;35:249-56.
35. Miyasaka K, Masuda M, Kawanami T, Funakoshi A. Neurohormonal regulation of pancreatic exocrine function in rats without gene expression of the cholecystokinin-A receptor. Pancreas 1996;12:272-9.
36. Hashimura N. Effect of oral administration of trypsin inhibitor following induction of pancreatitis with DL-ethionine in the rat: histopathological and immunohistochemical study with a CCK receptor antagonist (in Japanese with English abstract). J Jpn Panc Soc 1994;9:116-27.
37. Silverman M, Ilardi C, Bank S, Kranz V, Lendvai S. Effects of the cholecystokinin receptor antagonist L-364,718 on experimental pancreatitis in mice. Gastroenterology 1989;96:186-92.
38. Ohshio G, Saluja A, Leli U, Sengupta A, Steer ML. Failure of a potent cholecystokinin antagonist to protect against diet-induced pancreatitis in mice. Pancreas 1989;4:739-43.