Evaluation of the effect of steviol on chromosomal damage using micronucleus test in three laboratory animal species

Journal of the Medical Association of Thailand

Volumn 83, Issue SUPPL. 1, 2000, Pages

  Glinsukon, Thirayudh ^a  

^a RANGSIT UNIVERSITY   (Thailand)

Author keywords

Chromosomal Damage; Micronucleus Test; Steviol

Indexed keywords

DITERPENE; KAURANE DERIVATIVE; STEVIOL;

ANIMAL; ARTICLE; CHROMOSOME; CHROMOSOME ABERRATION; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HAMSTER; MALE; MICRONUCLEUS TEST; MOUSE; MOUSE STRAIN; ORAL DRUG ADMINISTRATION; RAT; REFERENCE VALUE; SPECIES DIFFERENCE; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; CHROMOSOME ABERRATIONS; CHROMOSOMES; CRICETINAE; DITERPENES; DITERPENES, KAURANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; MICE; MICE, INBRED STRAINS; MICRONUCLEUS TESTS; RATS; RATS, WISTAR; REFERENCE VALUES; SPECIES SPECIFICITY;

EID: 0041550467     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Fujita H, Edahiro T. Safety and utilization of Stevia sweetener. Shokuhinkougyo 1979; 22: 66-72.
2. Kazuyama S. Present status of sweeteners from Stevia. Shokuhin Kagaku 1979; 21:90-4.
3. Tsuchiya S. Sweeteners in pickled food. New Food Ind (Japan) 1979; 21: 12-5.
4. Matsui M, Matsui K, Kawasaki Y, et al. Evaluation of the genotoxicity of stevioside and steviol using six in vitro and one in vivo mutagenicity assays. Mutagenesis 1996; 573-9.
5. Meddle JA, Hite M, Kirkhart B, et al. The induction of micronuclei as a measure of genotoxicity. A Report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutation Res 1983; 123:61-118.